https://elifesciences.org/articles/94795v1
Early steps of protein disaggregation by Hsp70 chaperone and class B J-domain proteins are shaped...
Recovery of proteins from aggregates by Hsp70 is boosted by the Hsp110 co-chaperone, which promotes abundant Hsp70 recruitment to aggregates and supports...
https://elifesciences.org/articles/31668/peer-reviews
Peer review in Hsf1 and Hsp70 constitute a two-component feedback loop that regulates the yeast...
Dynamic regulation of the heat shock response depends on a negative feedback loop in which Hsf1 activates expression of Hsp70 and Hsp70 specifically and...
https://elifesciences.org/articles/94795/figures
Figures and data in Early steps of protein disaggregation by Hsp70 chaperone and class B J-domain...
Recovery of proteins from aggregates by Hsp70 is boosted by the Hsp110 co-chaperone, which promotes abundant Hsp70 recruitment to aggregates and supports...
https://www.mdpi.com/1422-0067/23/8/4464
Chaperone Hsp70 (HSPA1) Is Involved in the Molecular Mechanisms of Sleep Cycle Integration
The molecular mechanisms of sleep cycle integration at the beginning and the end of the inactive period are not clear. Sleep cycles with a predominance of deep...
https://elifesciences.org/articles/48491
Efficient conversion of chemical energy into mechanical work by Hsp70 chaperones | eLife
A multiscale modeling approach reveals how the energy from ATP hydrolysis is used by Hsp70 chaperones to remodel the conformation of their substrates through a...
chemical energy
https://elifesciences.org/articles/31668
Hsf1 and Hsp70 constitute a two-component feedback loop that regulates the yeast heat shock...
Dynamic regulation of the heat shock response depends on a negative feedback loop in which Hsf1 activates expression of Hsp70 and Hsp70 specifically and...
https://elifesciences.org/articles/64977v2
Unique integrated stress response sensors regulate cancer cell susceptibility when Hsp70 activity...
integrated stress response
https://www.frontiersin.org/journals/cell-and-developmental-biology/articles/10.3389/fcell.2021.651367/full
Frontiers | Adenosine Receptor and Its Downstream Targets, Mod(mdg4) and Hsp70, Work as a Signaling...
Adenosine (Ado) is an important signaling molecule involved in stress responses. Studies in mammalian models have shown that Ado regulates signaling mechanis...
https://pmc.ncbi.nlm.nih.gov/articles/PMC2999986/
Extremely low frequency electromagnetic fields activate the ERK cascade, increase hsp70 protein...
To use regenerating Planaria Dugesia dorotocethala as a model to determine whether an intermittent modulated extremely low frequency electro-magnetic field...
extremely low frequencyelectromagnetic fields
https://www.frontiersin.org/journals/cellular-neuroscience/articles/10.3389/fncel.2023.1131683/full
Frontiers | Involvement of heat shock proteins HSP70 in the mechanisms of endogenous...
This analytical review summarizes literature data and our own research on HSP70-dependent mechanisms of neuroprotection and discusses potential pharmacologic...
heat shock proteinsfrontiersinvolvement
https://elifesciences.org/articles/23471
Modeling Hsp70/Hsp40 interaction by multi-scale molecular simulations and coevolutionary sequence...
Integration of complementary computational approaches reveals an evolutionarily conserved interaction interface between molecular chaperones Hsp70 and Hsp40,...
multi scale
https://www.bas.ac.uk/data/our-data/publication/antarctic-marine-molluscs-do-have-an-hsp70-heat-shock-response/
Antarctic marine molluscs do have an HSP70 heat shock response - British Antarctic Survey
The success of any organism depends not only on niche adaptation but also the ability to survive environmental perturbation from homeostasis, a situation...
heat shock response
https://www.uni-heidelberg.de/en/node/26456/chemical-interference-with-the-activity-of-the-human-hsp70-chaperone-machinery-in-the-disaggregation?overlay=contact
Chemical interference with the activity of the human Hsp70 chaperone machinery in the...
chemical interferencewith theactivity
https://www.rcsb.org/structure/3D2E
RCSB PDB - 3D2E: Crystal structure of a complex of Sse1p and Hsp70, Selenomethionine-labeled...
Crystal structure of a complex of Sse1p and Hsp70, Selenomethionine-labeled crystals
https://pmc.ncbi.nlm.nih.gov/articles/PMC10447550/
Capsaicin binds the N-terminus of Hsp90, induces lysosomal degradation of Hsp70, and enhances the...
Heat shock protein 90 (Hsp90) and its co-chaperones promote cancer, and targeting Hsp90 holds promise for cancer treatment. Most of the efforts to harness this...
https://www.wikidata.org/wiki/Q36594740
The common variant of cystic fibrosis transmembrane conductance regulator is recognized by hsp70...
scientific article published on October 1993
https://www.frontiersin.org/journals/molecular-biosciences/articles/10.3389/fmolb.2022.947203/full
Frontiers | Inhibition of Plasmodium falciparum Hsp70-Hop partnership by 2-phenylthynesulfonamide
Plasmodium falciparum Hsp70-1 (PfHsp70-1; PF3D7_0818900) and PfHsp90 (PF3D7_0708400) are essential cytosol localized chaperones of the malaria parasite. The ...
plasmodium falciparumby 2frontiersinhibition
https://www.ncbi.nlm.nih.gov/Structure/pdb/5BN8
5BN8: Crystal structure of nucleotide-free human Hsp70 NBD
Heat shock 70 kDa protein 1A4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACIDCHLORIDE IONMAGNESIUM IONPHOSPHATE IONSODIUM ION
crystal structurenucleotidefreehumanhsp70
https://www.mdpi.com/2072-6651/4/10/768
Antibody to Heat Shock Protein 70 (HSP70) Inhibits Human T-Cell Lymphoptropic Virus Type I (HTLV-I)...
Adult T cell leukemia is a fatal malignant transformation caused by the human T-cell lymphoptropic virus type I (HTLV-I). HTLV-I is only associated with the...
https://www.ncbi.nlm.nih.gov/protein/146092550?report=GenPept
putative heat-shock protein hsp70 [Leishmania infantum JPCM5] - Protein - NCBI
heat shock proteinleishmania infantumputativehsp70ncbi
https://www.spandidos-publications.com/10.3892/or.2013.2814?text=fulltext
Downregulation of Hsp70 inhibits apoptosis induced by sialic acid-binding lectin (leczyme)
Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.
https://www.longdom.org/abstract/jatropha-curcas-linn-can-reduce-the-expression-of-hsp70-that-will-result-in-reduced-errors-in-protein-folding-and-promot-14141.html
Jatropha Curcas Linn can Reduce the Expression of Hsp70 that | 14141
Background: Jatropha curcas (J. curcas) as a local plant have phytochemical contents like phenolic that effect as anti-inflammatory and cytotoxicity...
jatropha curcasthe expressionlinnreduce
https://pmc.ncbi.nlm.nih.gov/articles/PMC8619557/
Molecular Mechanisms of Hypertensive Nephropathy: Renoprotective Effect of Losartan through Hsp70 -...
Hypertensive nephrosclerosis is the second most common cause of end-stage renal disease after diabetes. For years, hypertensive kidney disease has been focused...
hypertensive nephropathymolecularmechanismsrenoprotectiveeffect
https://elifesciences.org/reviewed-preprints/94795
Early Steps of Protein Disaggregation by Hsp70 Chaperone and Class B J-Domain Proteins are Shaped...
https://www.rcsb.org/structure/5AQS
RCSB PDB - 5AQS: Fragment-based screening of HSP70 sheds light on the functional role of...
Fragment-based screening of HSP70 sheds light on the functional role of ATP-binding site residues
https://www.ncbi.nlm.nih.gov/Structure/pdb/5AQF
5AQF: Fragment-based screening of HSP70 sheds light on the functional role of ATP-binding site...
BAG FAMILY MOLECULAR CHAPERONE REGULATOR 1HEAT SHOCK COGNATE 71 KDA PROTEIN2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOLADENOSINEGLYCEROL
https://www.wikidata.org/wiki/Q27938574
CDK-dependent Hsp70 Phosphorylation controls G1 cyclin abundance and cell-cycle progression -...
https://www.ncbi.nlm.nih.gov/protein/66356390?report=GenPept
heat shock 70 (HSP70) protein, partial [Cryptosporidium parvum Iowa II - Protein - NCBI
heat shockcryptosporidium parvum70protein
https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2020.01860/full
Frontiers | Corrigendum: Phloroglucinol-Mediated Hsp70 Production in Crustaceans: Protection...
Corrigendum on: Kumar, V., Baruah, K., Nguyen, D.V., Smagghe, G., Vossen, E. and Bossier, P., 2018. Phloroglucinol-mediated Hsp70 production in crustaceans: ...
frontierscorrigendumphloroglucinolmediatedhsp70
https://www.thermofisher.com/antibody/product/HSP70-Antibody-Polyclonal/PA5-28003
HSP70 Polyclonal Antibody | Invitrogen (PA5-28003)
Detect HSP70 in WB, ICC/IF, IHC (P), IP, ELISA. Reacts with Mouse, Rabbit, Rat, Chicken, Llama. Cited in 10 publications. Catalog # PA5-28003
polyclonal antibodyhsp70invitrogenpa5
https://www.mdpi.com/2072-6694/17/7/1224
Targeting Hsp70 Immunosuppressive Signaling Axis with Lipid Nanovesicles: A Novel Approach to Treat...
Background: Despite many efforts to effectively treat PDAC, PDAC carries one of the highest mortality rates of all major cancers. Thus, there is a critical...
https://www.uni-heidelberg.de/en/node/26456/chemical-interference-with-the-activity-of-the-human-hsp70-chaperone-machinery-in-the-disaggregation
Chemical interference with the activity of the human Hsp70 chaperone machinery in the...
chemical interferencewith theactivity
https://www.preprints.org/manuscript/202002.0364
HSP70/IL-2 Treated NK Cells Effectively Cross the Blood Brain Barrier and Target Tumor Cells in a...
Natural killer (NK) cell therapy is one of the most promising treatments for Glioblastoma Multiforme (GBM). However, this emerging technology is limited by the...
https://elifesciences.org/articles/56773/peer-reviews
Peer review in Phosphatidylinositol 3-phosphate and Hsp70 protect Plasmodium falciparum from...
Phosphatidylinositol 3-phosphate interacts with PfHsp70-1 and stabilizes the Plasmodium digestive vacuole under febrile temperatures.
peer review
https://www.rcsb.org/structure/5AQX
RCSB PDB - 5AQX: Fragment-based screening of HSP70 sheds light on the functional role of...
Fragment-based screening of HSP70 sheds light on the functional role of ATP-binding site residues
https://www.muni.cz/vyzkum/publikace/1491799
Human Stress-inducible Hsp70 Has a High Propensity to Form ATP-dependent Antiparallel Dimers That...