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Hydroxychloroquine reduces T cells activation recall antigen responses | PLOS One
Background In the context of the current COVID-19 pandemic, there is still limited information about how people suffering from autoimmune diseases respond to...
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https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2022.935370/full
Frontiers | Hydroxychloroquine, azithromycin and methylprednisolone and in hospital survival in...
Apr 29, 2026 - Introduction: Severe COVID-19 pneumonia has two phases that are not mutually exclusive. Repurposed drugs target only one phase and the association of combina...
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Objective We aimed to compare the safety and efficacy of a doxycycline-based regimen against Cameroon National Standard Guidelines (hydroxychloroquine plus...
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Lopinavir-ritonavir and hydroxychloroquine for critically ill patients with COVID-19: REMAP-CAP...
Jul 12, 2021 - To study the efficacy of lopinavir-ritonavir and hydroxychloroquine in critically ill patients with coronavirus disease 2019 (COVID-19). Critically ill adu
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Low dose of hydroxychloroquine is associated with reduced COVID-19 mortality: a multicenter study...
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Randomized controlled trial of favipiravir, hydroxychloroquine, and standard care in patients with...
Sep 26, 2022 - Favipiravir has antiviral activity against influenza, West Nile virus, and yellow fever virus and against flaviviruses. The objective of this pilot study was...
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Pharmacokinetic Basis of the Hydroxychloroquine Response in COVID-19: Implications for Therapy and...
Aug 11, 2020 - Chloroquine/hydroxychloroquine has recently been the subject of intense debate regarding its potential antiviral activity against SARS-Cov-2, the etiologic
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"The Effect of Hydroxychloroquine on In-Hospital Mortality in COVID-19" by Samar Aboulenain, Nakeya...
Background: Hydroxychloroquine (HCQ) is an antimalarial medication that has been tested against various viral illnesses. The available evidence regarding the...
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Update on use of chloroquine/hydroxychloroquine to treat coronavirus disease 2019 (COVID-19)
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Apr 27, 2021 - Despite several studies designed to evaluate the efficacy of chloroquine and hydroxychloroquine in the treatment of coronavirus disease 2019 (COVID-19), there...
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Hydroxychloroquine and tocilizumab therapy in COVID-19 patients—An observational study | PLOS One
Hydroxychloroquine has been touted as a potential COVID-19 treatment. Tocilizumab, an inhibitor of IL-6, has also been proposed as a treatment of critically...
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Apr 22, 2020 - Coronavirus patients taking hydroxychloroquine, a treatment touted by President Trump, were no less likely to need mechanical ventilation and had higher deaths...
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Hydroxychloroquine-mediated inhibition of SARS-CoV-2 entry is attenuated by TMPRSS2 | PLOS Pathogens
Author summary The novel pathogenic coronavirus SARS-CoV-2 causes COVID-19 and remains a threat to global public health. Chloroquine and hydroxychloroquine...
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Impact of prophylactic hydroxychloroquine on ultrastructural impairment and cellular SARS-CoV-2...
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Lack of efficacy of hydroxychloroquine and azithromycin in patients hospitalized for COVID-19...
Background Hydroxychloroquine combined with azithromycin (HCQ/AZI) has initially been used against coronavirus disease-2019 (COVID-19). In this retrospective...
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COVID-19 Evidence Accelerator: A parallel analysis to describe the use of Hydroxychloroquine with...
Background The COVID-19 pandemic remains a significant global threat. However, despite urgent need, there remains uncertainty surrounding best practices for...
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Is hydroxychloroquine beneficial for COVID-19 patients? | Cell Death & Disease
Jul 8, 2020 - The outbreak of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was first reported in December 2019....
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Chloroquine and Hydroxychloroquine in the USA: Uses, Safety, and Clinical Context
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Hydroxychloroquine for prophylaxis of COVID-19 in health workers: A randomized clinical trial |...
Introduction Health care workers are at high risk of being infected with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Our aim is to...
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The efficacy and safety of hydroxychloroquine for COVID-19 prophylaxis and clinical assessment: an...
The efficacy and safety of hydroxychloroquine for COVID-19 prophylaxis and clinical assessment: an updated meta-analysis of randomized trials
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Mortality outcomes with hydroxychloroquine and chloroquine in COVID-19 from an international...
May 14, 2021 - Substantial COVID-19 research investment has been allocated to randomized clinical trials (RCTs) on hydroxychloroquine/chloroquine, which currently face...
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Chloroquine and hydroxychloroquine as ACE2 blockers to inhibit viropexis of 2019-nCoV Spike...
The novel coronavirus disease (2019-nCoV) has been affecting global health since the end of 2019 and there is no sign that the epidemic is abating . The major...
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Evaluation of hydroxychloroquine or chloroquine for the prevention of COVID-19 (COPCOV): A...
In a randomised controlled trial, William Schilling and co-workers investigate potential prevention of COVID-19 by chloroquine or hydroxychloroquine.
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COVID-19 in Individuals Treated With Long-Term Hydroxychloroquine: A Propensity Score-Matched...
Jan 1, 1970 - INTRODUCTION Early in the COVID-19 pandemic, anti-malarial agent hydroxychloroquine (HCQ) was touted as a potentially effective COVID-19 treatment due to its...
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The ‘myth of Hydroxychloroquine (HCQ) as post-exposure prophylaxis (PEP) for the prevention of...
Jan 7, 2023 - The efficacy of Hydroxychloroquine (HCQ) as post-exposure prophylaxis (PEP) for the prevention of COVID-19 was contentious. In this randomized control...
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Frontiers | Combined Prophylactic and Therapeutic Use Maximizes Hydroxychloroquine Anti-SARS-CoV-2...
Apr 29, 2026 - While the SARS-CoV-2 pandemic is heavily hitting the world, it is of extreme importance that significant in vitro observations guide the quick set up of clin...
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The association of treatment with hydroxychloroquine and hospital mortality in COVID-19 patients |...
Sep 30, 2020 - This study investigates the association between the treatment with hydroxychloroquine and mortality in patients admitted with COVID-19. Routinely recorded,
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No benefit of hydroxychloroquine on SARS-CoV-2 viral load reduction in non-critical hospitalized...
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Hydroxychloroquine blocks SARS-CoV-2 entry into the endocytic pathway in mammalian cell culture |...
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Favipiravir and Hydroxychloroquine Combination Therapy in Patients with Moderate to Severe COVID-19...
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Background: During the initial phases of the COVID-19 pandemic, there was an unfounded fervor surrounding the use of hydroxychloroquine (HCQ) and tocilizumab...
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Efficacy of early hydroxychloroquine treatment in preventing COVID-19 pneumonia aggravation, the...
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