hypocretin - Robuta Search

https://pmc.ncbi.nlm.nih.gov/articles/PMC3589707/ The physiological role of orexin/hypocretin neurons in the regulation of sleep/wakefulness and... The hypothalamus monitors body homeostasis and regulates various behaviors such as feeding, thermogenesis, and sleeping. Orexins (also known as hypocretins)... https://elifesciences.org/articles/32637 Hypocretin underlies the evolution of sleep loss in the Mexican cavefish | eLife The identification of evolutionarily-derived changes in Hypocretin function within the brains of short-sleeping Mexican cavefish provides a system for... evolution of sleep hypocretin https://pmc.ncbi.nlm.nih.gov/articles/PMC5805467/ Discovery of hypocretin/orexin ushers in a new era of sleep research - PMC Prior to the 21st century, genetic mechanisms that regulate sleep were largely unknown. In 1998, de Lecea et al. 1 and Sakurai et al. 2 reported the discovery... a new era discovery of https://elifesciences.org/articles/07000/figures Figures and data in Norepinephrine is required to promote wakefulness and for hypocretin-induced... Experiments in genetically modified zebrafish that are unable to produce norepinephrine show that this neurotransmitter promotes wakefulness by mediating the... https://elifesciences.org/reviewed-preprints/97707v1 Neurons in the ventral striatopallidal complex modulate lateral hypothalamic orexin/hypocretin... in the lateral hypothalamic neurons ventral striatopallidal https://www.sri.com/publication/biosciences-health-pubs/animal-models-of-narcolepsy-and-the-hypocretin-orexin-system-past-present-and-future/ Animal Models of Narcolepsy and the Hypocretin/orexin System: Past, Present, and Future - SRI May 5, 2023 - Animal models have advanced not only our understanding of the etiology and phenotype of the sleep disorder narcolepsy but have also informed sleep/wake... animal models of narcolepsy https://www.sri.com/publication/biosciences-health-pubs/direct-inhibition-of-hypocretin-orexin-neurons-in-the-lateral-hypothalamus-by-nociceptin-orphanin-fq-blocks-stress-induced-analgesia-in-rats/ Direct inhibition of hypocretin/orexin neurons in the lateral hypothalamus by nociceptin/orphanin... Apr 12, 2023 - We tested the hypothesis that N/OFQ modulates the SIA directly via the inhibition of the Hcrt neurons in the lateral hypothalamus. https://www.ncbi.nlm.nih.gov/gene?cmd=Retrieve&dopt=summary&list_uids=3061 HCRTR1 hypocretin receptor 1 [Homo sapiens (human)] - Gene - NCBI hypocretin receptor homo sapiens human gene hcrtr1 ncbi