https://elifesciences.org/articles/21055
When the neuropeptide orexin is peripherally administered in mice with septic shock, it penetrates the blood-brain barrier and acts in the brain to improve...
of miceperipherallyorexinimprovessurvival
https://www.academia.edu/70951450/Effects_of_orexin_2_receptor_activation_on_apnea_in_the_C57BL_6J_mouse
May 26, 2025 - Background-The hypothesis was that an orexin 2 receptor (OX2R) agonist would prevent sleep-related disordered breathing. Methods-In C57BL/6J (B6) mice, body...
receptor activationpdfeffectsorexinapnea
https://www.sri.com/publication/biosciences-health-pubs/locus-coeruleus-and-tuberomammillary-nuclei-ablations-attenuate-hypocretin-orexin-antagonist-mediated-rem-sleep/
Hypocretin 1 and 2 (Hcrts; also known as orexin A and B), excitatory neuropeptides synthesized in cells located in the tuberal hypothalamus, play a central...
locus coeruleusnucleiablationsattenuatehypocretin
https://pubmed.ncbi.nlm.nih.gov/27480648/?dopt=Abstract
The hypocretin/orexin (HCRT) system is implicated in reward and reinforcement processes through actions on the mesolimbic dopamine (DA) system. Here we provide...
knock out micehypocretinorexindisplaydisrupted
https://elifesciences.org/articles/90158
Optogenetic manipulation and photometry recordings in the lateral hypothalamus show how interactions between dopamine and orexin systems underlie reward...
stimulationvtadopamineinputslh
https://www.frontiersin.org/journals/endocrinology/articles/10.3389/fendo.2018.00573/full
Orexins (OxA and OxB) also termed hypocretins are hypothalamic neuropeptides involved in central nervous system to control the sleep/wake process which is me...
frontiersantitumoralpropertiesorexin
https://europe.pharmalabglobal.com/orexin-a/
Buy Orexin A EUROPE from PharmaLabGlobal - Discover the potential benefits for wakefulness, cognitive performance and addiction.
orexin abuyeurope
https://pubmed.ncbi.nlm.nih.gov/11683899/?dopt=Abstract
Hypocretins/orexins are neuropeptides implicated in sleep regulation and the sleep disorder narcolepsy. In order to examine how hypocretin activity fluctuates...
orexin afluctuationextracellularhypocretinlevels