https://adisinsight.springer.com/drugsafety/803637617?error=cookies_not_supported&code=1c65511e-6fe1-4903-ae92-f1bf362fe9f8
Imatinib - AdisInsight
A man in his 20s [exact age at reaction onset not stated] developed myelotoxicity during treatment with imatinib for dermatofibrosarcoma protuberans.The man was
imatinibadisinsight
https://data.mendeley.com/datasets/ft27d96y63/1
CX-5461 potentiates imatinib-induced apoptosis in K562 cells by stimulating KIF1B expression (Part...
The selective RNA polymerase I inhibitor CX-5461 has been shown to be effective in treating some types of leukemic disorders. Emerging evidence suggests that...
https://www.cancerresearchuk.org/about-cancer/find-a-clinical-trial/a-trial-looking-at-imatinib-after-surgery-for-gastrointestinal-stromal-tumour-eortc-62024
A trial looking at imatinib after surgery for gastrointestinal stromal tumours (EORTC 62024)
This trial was trying to find out if drug called imatinib (Glivec) could stop or delay a gastrointestinal stromal tumour (GIST) coming back after surgery.
https://transportal.compbio.ucsf.edu/compounds/imatinib/
Imatinib
Transporter information for Imatinib.
imatinib
https://www.wikidata.org/wiki/Q35628978
The effects of imatinib mesylate treatment before allogeneic transplantation for chronic myeloid...
scientific article published on 24 October 2006
imatinib mesylate
https://www.news-medical.net/news/20121102/Imatinib-mesylate-effectively-treats-children-with-neurofibromatosis-type-1-tumors.aspx
Imatinib mesylate effectively treats children with neurofibromatosis type 1 tumors
Jun 19, 2019 - Physician-researchers at Indiana University School of Medicine have reported the first effective therapy for a class of previously untreatable and potentially...
imatinib mesylateeffectivelytreatschildrenneurofibromatosis
https://www.wikidata.org/wiki/Q37692798
Dasatinib or high-dose imatinib for chronic-phase chronic myeloid leukemia resistant to imatinib at...
scientific article published on September 2009
https://researchportal.helsinki.fi/sv/publications/short-and-long-term-effects-of-imatinib-in-hospitalized-covid-19-/
Short- and long-term effects of imatinib in hospitalized COVID-19 patients: A randomized trial -...
https://adisinsight.springer.com/drugsafety/801135897?error=cookies_not_supported&code=2f333bd9-6fda-4c87-8f31-323f822e0600
Imatinib - AdisInsight
A 76-year-old man developed multiple myeloma (MM) after receiving imatinib for chronic myeloid leukaemia; he subsequently died.After his diagnosis, the man was
imatinibadisinsight
https://pubmed.ncbi.nlm.nih.gov/22772433/
Understanding rechallenge and resistance in the tyrosine kinase inhibitor era: imatinib in...
Disease progression after treatment with a particular therapy, in the traditional view of cancer chemotherapy, indicates resistance to that treatment. However,...
in thetyrosine kinaseunderstandingresistance
https://adisinsight.springer.com/drugsafety/803879542?error=cookies_not_supported&code=46ee218f-1c1e-48e0-867a-0970efd6f13e
Imatinib - AdisInsight
In a study involving 123 patients conducted between July 2002 and August 2013, a patient [age and sex not stated] was described, who exhibited lack of efficacy
imatinibadisinsight
https://pubmed.ncbi.nlm.nih.gov/34052176/
Efficacy and Safety of Imatinib Treatment in Elderly Patients With Chronic Myeloid Leukemia:...
Upfront imatinib was generally well tolerated among elderly Turkish patients with CML with non-inferior responses and long-term outcomes when compared with...
efficacy and safety
https://adisinsight.springer.com/drugsafety/803832406?error=cookies_not_supported&code=05e0ce5f-8f38-4275-b1a9-fa0b098f9d23
Imatinib - AdisInsight
A 41-year-old woman developed intolerable gastrointestinal adverse reactions during the treatment with imatinib for gastrointestinal stromal tumor.The woman was
imatinibadisinsight
https://adisinsight.springer.com/drugsafety/803923343?error=cookies_not_supported&code=791f5016-0fb7-4c24-bf27-6a6785c88b7d
Imatinib - AdisInsight
A patient with chronic myeloid leukaemia developed undifferentiated blast crisis while receiving imatinib.
imatinibadisinsight
https://www.scirp.org/journal/PaperInformation?PaperID=44502
Regional Evaluation of Tolerability and Efficacy of Imatinib Mesylate in Patients with Chronic...
Sixty patients with Chronic Myeloid Leukemia (CML) who were on oral imatinib were included in this study. The study aimed to evaluate patients characteristic,...
https://seer.cancer.gov/oncologytoolbox/canmed/ndconc/82009-0086/
82009-0086 Imatinib Mesylate - CanMED: NDC
CanMED: NDC. The Cancer Medications Enquiry Database (CanMED) is a two-part resource for cancer drug treatment related studies.
imatinib mesylatendc
https://vivo.colorado.edu/display/meshid_D02.241.223.100.100.435
Acids, Carbocyclic - Imatinib Mesylate | CU Experts | CU Boulder
imatinib mesylateacidscuexpertsboulder
https://seer.cancer.gov/oncologytoolbox/canmed/ndconc/72485-0202/
72485-0202 Imatinib mesylate - CanMED: NDC
CanMED: NDC. The Cancer Medications Enquiry Database (CanMED) is a two-part resource for cancer drug treatment related studies.
imatinib mesylatendc
https://www.wikidata.org/wiki/Q58179557
Survival advantage from imatinib compared with the combination interferon- plus cytarabine in...
scientific article published on 20 April 2006
https://pubmed.ncbi.nlm.nih.gov/18029844/
CT and PET: early prognostic indicators of response to imatinib mesylate in patients with...
The two best metrics were the optimized PET SUVmax threshold of 3.4 at 1 month (p = 0.00002) and the optimized CT bidimensional measurement threshold (no...
https://researchconnect.buffalo.edu/en/publications/induction-of-imatinib-metabolism-by-hypericum-perforatum-3/
Induction of imatinib metabolism by hypericum perforatum [3] - SUNY University at Buffalo
hypericum perforatum
https://adisinsight.springer.com/drugsafety/803811727?error=cookies_not_supported&code=21fc948e-c5b3-454b-b0ae-058d5e9f9d15
Dasatinib/eltrombopag/imatinib - AdisInsight
A 56-year-old woman developed thrombocytopenia during treatment with dasatinib and imatinib for chronic-phase chronic myeloid leukemia (CP-CML). Additionally,
dasatinibeltrombopagimatinibadisinsight
https://portal.fis.tum.de/en/publications/secondary-malignancies-in-chronic-myeloid-leukemia-patients-after-2/
Secondary malignancies in chronic myeloid leukemia patients after imatinib-based treatment:...
chronic myeloid leukemiasecondary malignancies
https://pubmed.ncbi.nlm.nih.gov/23127201/
Monitoring and switching patterns of patients with chronic myeloid leukemia treated with imatinib...
Based on the guidelines, the rates of treatment monitoring and switching upon failure were low, demonstrating the need for improvement in CML care in community...
chronic myeloid leukemia
https://www.nice.org.uk/guidance/ta86/chapter/5-Recommendations-for-further-research
5 Recommendations for further research | Imatinib for the treatment of unresectable and/or...
Evidence-based recommendations on imatinib for treating unresectable or metastatic gastrointestinal stromal tumours in adults
further research
https://portal.research.lu.se/sv/publications/role-of-znf224-in-c-myc-repression-and-imatinib-responsiveness-in/fingerprints/
Role of ZNF224 in c-Myc repression and imatinib responsiveness in chronic myeloid leukemia -...
https://id.wikibooks.org/wiki/Istimewa:Pranala_balik/Informasi_Obat/Imatinib_mesilat
Halaman yang memiliki pranala ke "Informasi Obat/Imatinib mesilat" - Wikibuku bahasa Indonesia
informasi obat
https://ocw.mit.edu/courses/7-88j-protein-folding-and-human-disease-spring-2015/external-resources/bcr-abl-point-mutants-isolated-from-patients-with-imatinib-mesylate-resistant-chronic-mye51a1b63a-a762-4490-b23b-fc41f6c67889/
BCR-ABL Point Mutants Isolated from Patients with Imatinib Mesylate-resistant Chronic Myeloid...
MIT OpenCourseWare is a web based publication of virtually all MIT course content. OCW is open and available to the world and is a permanent MIT activity
https://pubmed.ncbi.nlm.nih.gov/20007927/
Imatinib treatment for idiopathic pulmonary fibrosis: Randomized placebo-controlled trial results
In a randomized, placebo-controlled trial of patients with mild to moderate IPF followed for 96 weeks, imatinib did not affect survival or lung function....
idiopathic pulmonary fibrosisplacebo controlled trialtreatment forimatinib
https://pmc.ncbi.nlm.nih.gov/articles/PMC5697457/
Molecular Response to Imatinib and Its Correlation with mRNA Expression Levels of Imatinib Influx...
Imatinib mesylate is approved for the treatment of Chronic Myeloid Leukemia (CML). About 20% of patients with CML do not respond to treatment with Imatinib...
https://kclpure.kcl.ac.uk/portal/en/publications/imatinib-optimized-therapy-improves-major-molecular-response-rate/
Imatinib Optimized Therapy Improves Major Molecular Response Rates in Patients with Chronic Myeloid...
https://pubmed.ncbi.nlm.nih.gov/39745285/
Efficacy and Safety of Treating Pulmonary Arterial Hypertension With Imatinib: A Meta-Analysis of...
Pulmonary vascular remodeling and arterial hypertension (PAH) correlate with increased platelet-derived growth factor activity and elevated KIT expression....
efficacy and safety
https://eprints.ncl.ac.uk/151017
Outcomes by cytogenetic and molecular response at 12 and 18 months of imatinib in patients with...
https://pubmed.ncbi.nlm.nih.gov/35015587/
Indication-Specific Generic Uptake of Imatinib Demonstrates the Impact of Skinny Labeling
Generic versions of imatinib were dispensed frequently for indications both included (CML) and excluded (GIST) from the skinny labeling, although patients with...
the impactindicationspecificgenericuptake
https://adisinsight.springer.com/drugsafety/803112195?error=cookies_not_supported&code=f368d449-0e9b-416d-954a-a0b4f7c4a409
Imatinib - AdisInsight
A 46-year-old woman developed acute liver failure while receiving imatinib.The woman had a history of a pelvic gastrointestinal stromal tumour. She started
imatinibadisinsight
https://cureresearch4type1diabetes.blogspot.com/2014/03/imatinib-gleevec-glivec-finally-starts.html
Current Research into Cures for Type-1 Diabetes: Imatinib ("Gleevec" / "Glivec") Finally Starts a...
A year ago, researchers (Drs. Gitelman and Bluestone) at UCSF filed the paperwork to start a clinical trial testing Gleevec on people. Now,...
https://experts.umn.edu/en/publications/response-monitoring-tolerability-and-effectiveness-of-imatinib-tr/
Response monitoring, tolerability, and effectiveness of imatinib treatment for chronic myeloid...
treatment forresponsemonitoringtolerabilityeffectiveness
https://pediatrics.ucsf.edu/node/324146
The EBF1-PDGFRB T681I mutation is highly resistant to imatinib and dasatinib in vitro and...
https://forsaljningavaktieryzqu.web.app/71065/3864.html
Imatinib and gastrointestinal stromal tumors: Where do we go
imatinibgastrointestinaltumorsgo
https://pubs.rsc.org/en/content/articlelanding/2021/AN/D0AN01860K
An SPR investigation into the therapeutic drug monitoring of the anticancer drug imatinib with...
The anticancer drug imatinib is often involved in therapeutic drug monitoring (TDM) studies aimed at improving the treatment of several forms of leukemia and...
therapeutic drug monitoring
https://pubmed.ncbi.nlm.nih.gov/41225551/
Cytogenetic profile of chronic myeloid leukaemia patients resistant to imatinib at tertiary level...
Cytogenetic anomalies such as trisomy 8, trisomy 19, and complex karyotypes may contribute to TKI resistance. Further study is needed to understand additional...
chronic myeloid leukaemia
https://pubmed.ncbi.nlm.nih.gov/24456693/
BCR-ABL kinase domain mutations, including 2 novel mutations in imatinib resistant Malaysian...
Discovery of imatinib mesylate (IM) as the targeted BCR-ABL protein tyrosine kinase inhibitor (TKI) has resulted in its use as the frontline therapy for...
abl kinase
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0090795
Imatinib Mesylate Exerts Anti-Proliferative Effects on Osteosarcoma Cells and Inhibits the Tumour...
Osteosarcoma is the most common primary malignant bone tumour characterized by osteoid production and/or osteolytic lesions of bone. A lack of response to...
https://pubmed.ncbi.nlm.nih.gov/17200352/
Pathologic and molecular heterogeneity in imatinib-stable or imatinib-responsive gastrointestinal...
The histologic response to imatinib is heterogeneous and does not correlate well with clinical response. Second-site KIT mutations are rare in...
pathologicmolecularheterogeneityimatinibstable
https://infoscience.epfl.ch/entities/publication/a1451316-e342-4d9c-8da6-e69c139ce282
Medical Guidelines Reconciling Medical Software and Electronic Devices: Imatinib Case-study
Nowadays medical software is tightly coupled with medical devices that perform patient state monitoring and lately even some basic treatment procedures....
medical guidelineselectronic devicesreconcilingsoftwareimatinib
https://pmc.ncbi.nlm.nih.gov/articles/PMC3010822/
Principal long-term adverse effects of imatinib in patients with chronic myeloid leukemia in...
Imatinib mesylate (IM), an original Abl tyrosine kinase inhibitor, entered the clinics in 1998 for the treatment of patients with chronic myeloid leukemia...
https://cordis.europa.eu/project/id/101005142/es
Development of Impentri, an intravenous imatinib formulation for Covid-19 acute respiratory...
The accumulation of fluid in the lungs is a significant feature of the pathology in patients with severe Covid-19 infection. This build up of fluid,...
https://www.cancerresearchuk.org/about-cancer/find-a-clinical-trial/a-trial-looking-at-imatinib-for-children-and-young-people-with-acute-lymphoblastic-leukaemia
A trial looking at imatinib (Glivec) for children and young people with acute lymphoblastic...
This trial looked at imatinib (Glivec) for children and young people with Philadelphia positive acute lymphoblastic leukaemia (ALL).
for children and young people
https://eprints.ncl.ac.uk/85930
Imatinib improves but may not fully reverse the poor prognosis of patients with CML with derivative...
https://www.wikidata.org/wiki/Q80200756
Isodicentric Philadelphia chromosomes in imatinib mesylate (Gleevec)-resistant patients - Wikidata
scientific article published on 01 April 2007
imatinib mesylatephiladelphiachromosomesgleevecresistant
https://arup.utah.edu/media/shortTopics/spot_mcmillin_imatinib_2017/videoLecture.php
Educational Resources - Spotlight on Testing: Imatinib - Therapeutic Drug Monitoring
educational resourcesspotlighttestingimatinibtherapeutic
https://adisinsight.springer.com/drugsafety/803883940?error=cookies_not_supported&code=5e1ad03c-b2a9-44ea-9b39-4e24cc98072f
Dasatinib/imatinib/prednisolone - AdisInsight
A 60-year-old woman developed Epstein-Barr virus (EBV) associated lymphoproliferative disorder (LPD) during treatment with dasatinib and prednisolone for
dasatinibimatinibprednisoloneadisinsight
https://www.mdpi.com/2072-6694/15/1/143
Identification of Thiazolo[5,4-b]pyridine Derivatives as c-KIT Inhibitors for Overcoming Imatinib...
c-KIT is a promising therapeutic target against gastrointestinal stromal tumor (GIST). In order to identify novel c-KIT inhibitors capable of overcoming...
https://adisinsight.springer.com/trials/700241810?error=cookies_not_supported&code=e62a009d-81fc-48e2-8ea9-639b730a2b68
Pilot study: Imatinib for the treatment of plexiform neurofibromas in NF1 patients. [Studio pilota...
This study is investigating the efficacy and safety of imatinib in patients with neurofibromatoses (NF1) and plexiform neurofibromas. The primary endpoint is
https://adisinsight.springer.com/drugsafety/801026847?error=cookies_not_supported&code=03d51424-32a1-4a8f-b4ea-6c74b8b412d8
Imatinib/sunitinib - AdisInsight
A 73-year-old woman developed hypothyroidism while receiving imatinib, then sunitinib, for metastatic gastrointestinal stromal cancer.The woman was receiving
imatinibsunitinibadisinsight
https://www.cancerresearchuk.org/about-cancer/treatment/drugs/imatinib
Imatinib (Glivec) | Cancer drugs | Cancer Research UK
Imatinib (Glivec) is a targeted cancer drug. It as a treatment for several types of cancer. Find out how you have it and possible side effects.
cancer drugsimatinibglivecresearchuk
https://publikationen.uni-tuebingen.de/xmlui/handle/10900/55307
Cellular Uptake of Imatinib into Leukemic Cells Is Independent of Human Organic Cation Transporter...
https://pmc.ncbi.nlm.nih.gov/articles/PMC6440723/
Efficacy and Tolerability of 5-Year Adjuvant Imatinib Treatment for Patients With Resected...
This phase 2, multi-institutional clinical trial assesses whether patients with resected primary gastrointestinal stromal tumor receiving 5 years of adjuvant...