https://pubmed.ncbi.nlm.nih.gov/19074458/
Autosomal recessive retinal diseases caused by mutations in the ABCA4 gene are being considered for gene replacement therapy. All individuals with...
disease progressiongene therapyproposedstrategy
https://www.sciencedaily.com/releases/2020/04/200417141839.htm
Early treatment with the experimental antiviral drug remdesivir significantly reduced clinical disease and damage to the lungs of rhesus macaques infected with...
disease progressionantiviralremdesivirmonkeyscovid
https://www.elsevier.es/en-revista-neurologia-english-edition--495-articulo-nutritional-status-assessment-in-alzheimer-S217358082100167X
IntroductionNutritional deficiencies are frequent in Alzheimer disease (AD), even in
alzheimer diseasenutritionalstatusassessmentinfluence
https://pubmed.ncbi.nlm.nih.gov/41527491/?utm_source=SimplePie&utm_medium=rss&utm_campaign=pubmed-2&utm_content=1VUFS2KU_hFnBUajs3hlb00hHBOGRVXZp7ZhDB0wD6N0LBD9Nk&fc=20250423082013&ff=20260113113657&v=2.18.0.post22+67771e2
ALKBH5-modified UC-MSCs Exo reduced TRAF6 expression by demethylating its m6A sites, promoting M2 macrophage polarisation and alleviating DKD progression....
diabetic kidney diseaseprogressionmicemediated
https://www.technologynetworks.com/neuroscience/news/genotype-found-30-percent-als-patients-speeds-disease-progression-282687
Mice bred to carry a gene variant found in a third of ALS patients have a faster disease progression and die sooner than mice with the standard genetic model...
found ingenotypepercentalspatients
https://ctti-clinicaltrials.org/about/ctti-projects/disease-progression-modeling/ctti-recommendations-disease-progression-modeling/
Sep 25, 2025 - These recommendations aim to highlight the unique benefits of using disease progression modeling in medical product development, when it should be considered...
disease progressionrecommendationsmodeling
https://www.healthshots.com/preventive-care/self-care/huntingtons-disease-progression-slowed-by-75-with-gene-therapy/
Sep 25, 2025 - For the first time, Huntington’s disease has been successfully treated with a new gene therapy, AMT-130, which slows the disease by 75 percent, targeting the...
disease progressiongene therapyslowed
https://pubmed.ncbi.nlm.nih.gov/18709007/
Timely recognition of risk factors for CKD progression and their treatment by correction of high blood pressure, reduction of proteinuria, correction of...
chronic kidney diseaseslowprogression
https://www.brown.edu/news/2025-08-01/alzheimers-biomarker
Researchers at the Carney Institute for Brain Science have identified electrical activity in the brain that could predict progression to Alzheimer’s disease.
brown universityneuroscientistshelpidentifybiomarker
https://www.ajmc.com/view/type-2-diabetes-associated-with-increased-risk-faster-progression-of-parkinson-disease
A study finds type 2 diabetes associated with an increased risk of developing Parkinson disease (PD), as well as faster progression of motor symptoms in those...
typediabetesassociatedincreasedrisk
https://www.statnews.com/2025/09/24/huntingtons-gene-therapy-uniqure/
Sep 24, 2025 - Results are likely to support the first approval of a genetic treatment for the rare neurodegenerative condition.
gene therapydisease progressionuniqureslowedkey
https://newatlas.com/als-mnd-drug-clinical-trial-success/58026/?amp=true
Amyotrophic lateral sclerosis (ALS) is a devastating disease that usually claims the lives of patients within a few years. But now a new drug developed by a...
disease progressionclinical trialnewalsdrug
https://www.news-medical.net/news/20240522/Improved-animal-model-captures-full-picture-of-periodontal-disease-progression.aspx
Periodontal disease, represented by periodontitis, is the leading cause of tooth loss and affects close to one in five adults worldwide.
animal modelpicture ofperiodontal diseaseimprovedcaptures