https://sciencedaily.com/releases/2022/07/220712141324.htm
Tumors with specific genetic mutations show response to immune checkpoint blockade therapy |...
New research shows that pathogenic polymerase epsilon and delta (POLE/POLD1) genetic mutations lead to improved response to immune checkpoint blockade, a...
immune checkpoint blockadegenetic mutations
https://scholarshare.temple.edu/entities/publication/2f14dc21-8f87-49c3-bbc5-7d75ca46ba8b
PD-1/PD-L1 immune-checkpoint blockade induces immune effector cell modulation in metastatic...
Peripheral immune-checkpoint blockade with mAbs to programmed cell death receptor-1 (PD-1) (either nivolumab or pembrolizumab) or PD-Ligand-1 (PD-L1)...
immune checkpoint blockade
https://pmc.ncbi.nlm.nih.gov/articles/PMC10997156/
Neoadjuvant Immune Checkpoint Blockade Enhances Local and Systemic Tumor Immunity in Head and Neck...
Neoadjuvant (pre-surgical) immune checkpoint blockade (ICB) has shown promising clinical activity in head and neck cancer and other cancers, including FDA...
immune checkpoint blockade
https://www.cruk.cam.ac.uk/publications/multiparametric-mri-of-early-tumor-response-to-immune-checkpoint-blockade-in-metastatic-melanoma-2/
Multiparametric MRI of Early Tumor Response to Immune Checkpoint Blockade in Metastatic Melanoma -...
Authors: D Lau, MA McLean, AN Priest, AB Gill, F Scott, I Patterson, B Carmo, F Riemer, JD Kaggie, A Frary, D Milne, C Booth, A Lewis, M Sulikowski, L Brown,...
immune checkpoint blockade
https://pubmed.ncbi.nlm.nih.gov/25358693/
Beyond immune checkpoint blockade: new approaches to targeting host-tumor interactions in prostate...
This article highlights the most significant recent progress and unmet needs that were discussed at the meeting toward the goal of speeding the development of...
immune checkpoint blockade
https://pubmed.ncbi.nlm.nih.gov/29441437/?dopt=Abstract
Immune Checkpoint Blockade: The New Frontier in Cancer Treatment
Immune checkpoint blockers have revolutionized cancer treatment in recent years. These agents are now approved for the treatment of several malignancies,...
immune checkpoint blockadethe new frontiercancertreatment
https://medicinehealth.leeds.ac.uk/medicine/dir-record/research-opportunities/538/oncolytic-virus-immunotherapy-to-sensitise-liver-cancers-to-immune-checkpoint-blockade
Oncolytic virus immunotherapy to sensitise liver cancers to immune checkpoint blockade | School of...
Research opportunities
immune checkpoint blockadeoncolytic virus
https://experts.umn.edu/en/publications/immune-checkpoint-blockade-in-human-cancer-therapy-lung-cancer-an/
Immune checkpoint blockade in human cancer therapy: Lung cancer and hematologic malignancies -...
immune checkpoint blockadecancer therapyhuman
https://centerforimmunology.cornell.edu/interests/combinations-of-radiotherapy-immune-checkpoint-blockade/
Combinations Of Radiotherapy & Immune Checkpoint Blockade | Cornell Center for Immunology
immune checkpoint blockadecenter forcombinationsradiotherapycornell
https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2024.1487940/full
Frontiers | Concurrent immune checkpoint blockade for enhanced cancer immunotherapy utilizing...
Immune checkpoint inhibitors (ICIs) have revolutionized cancer treatment, demonstrating unprecedented efficacy against advanced cancers. However, their clini...
immune checkpoint blockadecancer immunotherapyfrontiersconcurrentenhanced
https://jcopodcast.libsyn.com/webpage/risky-business-pd-1-immune-checkpoint-blockade-in-thymic-epithelial-neoplasms
Journal of Clinical Oncology (JCO) Podcast: Risky Business: PD-1 Immune Checkpoint Blockade in...
This podcast discusses the important risks and potential benefits of PD-1 immune checkpoint blockade in patients with thymic epithelial neoplasms. Read the...
journal of clinical oncology
https://www.repository.cam.ac.uk/items/92fff947-35f4-452f-a0be-93f7583b20fe
Studying the B and plasma cell responses to the immune checkpoint blockade treatment of cancer
Immune checkpoint blockade (ICB) therapies targeting PD-1 and CTLA-4 have revolutionised cancer treatment. However, their efficacy is not completely...
https://pubmed.ncbi.nlm.nih.gov/37957378/
Association between pretreatment emotional distress and neoadjuvant immune checkpoint blockade...
Neoadjuvant immune checkpoint blockade (ICB) outperforms adjuvant ICB for treatment of stage IIIB-D melanoma, but potential biomarkers of response, such as...
emotional distressimmune checkpointassociationpretreatmentblockade
https://pubmed.ncbi.nlm.nih.gov/29320654/
Immune-Related Adverse Events Associated with Immune Checkpoint Blockade
Immune-Related Adverse Events Associated with Immune Checkpoint Blockade
adverse eventsassociated withimmunerelatedcheckpoint
https://dash.harvard.edu/entities/publication/92a10f90-9224-4d99-859a-6aaa42fc58c6
DDI2 inhibition promotes MHC class I antigen presentation and immune checkpoint blockade efficacy...
The landscape of cancer treatments has changed dramatically over the last ten years with the use of novel checkpoint blockade immunotherapy. Even though immune...
mhc class i
https://pubmed.ncbi.nlm.nih.gov/37308678/
Integrative analysis of risk factors for immune-related adverse events of checkpoint blockade...
Immune-related adverse events (irAEs) induced by checkpoint inhibitors involve a multitude of different risk factors. Here, to interrogate the multifaceted...
risk factors
https://pubmed.ncbi.nlm.nih.gov/41125896/
SARS-CoV-2 mRNA vaccines sensitize tumours to immune checkpoint blockade
sars covmrna vaccinesimmune checkpoint
https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2023.1264327/full
Frontiers | Combinatorial blockade for cancer immunotherapy: targeting emerging immune checkpoint...
The differentiation, survival, and effector function of tumor-specific CD8 + cytotoxic T cells lie at the center of antitumor immunity. Due to the lack of pr...
cancer immunotherapyfrontierscombinatorialblockadetargeting
https://pubmed.ncbi.nlm.nih.gov/33158814/
Enhanced Efficacy of Simultaneous PD-1 and PD-L1 Immune Checkpoint Blockade in High-Grade Serous...
Immune therapies have had limited efficacy in high-grade serous ovarian cancer (HGSC), as the cellular targets and mechanism(s) of action of these agents in...