ivacaftor - Robuta Search

https://adisinsight.springer.com/drugsafety/803928593?error=cookies_not_supported&code=56613a2b-f79e-47b7-8021-cfde8d763b64 Elexacaftor/ivacaftor/tezacaftor - AdisInsight Eleven patients [age and sex not stated] with cystic fibrosis in France were treated with elexacaftor-tezacaftor-ivacaftor and were reported as requiring lung adisinsight https://adisinsight.springer.com/trials/700251075?error=cookies_not_supported&code=2b3972aa-b4cb-4a96-8a64-d7a5c3b24a60 A Phase 3b, Open-Label Study to Evaluate Lumacaftor and Ivacaftor Combination Therapy in Subjects... The purpose of this study is to evaluate the safety and tolerability of LUM/IVA combination therapy in subjects 12 years and older with CF and advanced lung https://adisinsight.springer.com/drugsafety/803859699?error=cookies_not_supported&code=20e202b2-6c7c-43c6-8c20-55df31e4e9a6 Elexacaftor/Ivacaftor/tezacaftor - AdisInsight In a study of 447 children conducted between 2022 and 2023, a child [sex and exact age not stated] was described, who developed liver parameter elevation during adisinsight https://pubmed.ncbi.nlm.nih.gov/24973281/ A CFTR corrector (lumacaftor) and a CFTR potentiator (ivacaftor) for treatment of patients with... Vertex Pharmaceuticals, Cystic Fibrosis Foundation Therapeutics Development Network. https://pubmed.ncbi.nlm.nih.gov/30334692/ VX-445-Tezacaftor-Ivacaftor in Patients with Cystic Fibrosis and One or Two Phe508del Alleles The use of VX-445-tezacaftor-ivacaftor to target Phe508del CFTR protein resulted in increased CFTR function in vitro and translated to improvements in patients... https://researchconnect.buffalo.edu/en/publications/long-term-safety-and-efficacy-of-ivacaftor-in-patients-with-cysti/ Long-term safety and efficacy of ivacaftor in patients with cystic fibrosis who have the... https://adisinsight.springer.com/drugsafety/803926771?error=cookies_not_supported&code=31abb67b-e853-4412-8870-db2299e17227 Elexacaftor/ivacaftor/tezacaftor - AdisInsight Seventeen patients with cystic fibrosis who had undergone lung transplantation received elexacaftor/tezacaftor/ivacaftor and experienced adverse drug reactions adisinsight https://pubmed.ncbi.nlm.nih.gov/24081349/ Normalization of sweat chloride concentration and clinical improvement with ivacaftor in a patient... The cystic fibrosis (CF) protein forms an anion channel in epithelial cells, and the absence or defective function of this channel results in the clinical... https://pubmed.ncbi.nlm.nih.gov/38950554/ Behavioural and sleep issues after initiation of elexacaftor-tezacaftor-ivacaftor in preschool-age... Behavioural and sleep issues after initiation of elexacaftor-tezacaftor-ivacaftor in preschool-age children with cystic fibrosis https://adisinsight.springer.com/trials/700302222?error=cookies_not_supported&code=f8626582-c6bd-4233-9e32-d3e8a4008f2d Real world effectiveness of Ivacaftor in patients with cystic fibrosis: a multicenter,... The aim of this study is to evaluate real world effectiveness of Ivacaftor in patients with cystic fibrosis. real world in patients https://pubmed.ncbi.nlm.nih.gov/38226069/ Cystic fibrosis airway inflammation enables elexacaftor/tezacaftor/ivacaftor-mediated rescue of... cystic fibrosis airway inflammation https://www.mdpi.com/2077-0383/10/7/1527 Real-World Outcomes of Ivacaftor Treatment in People with Cystic Fibrosis: A Systematic Review Cystic fibrosis (CF) is a rare, progressive, multi-organ genetic disease. Ivacaftor, a small-molecule CF transmembrane conductance regulator modulator, was the... https://www.mayoclinic.org/es/drugs-supplements/ivacaftor-oral-route/description/drg-20075428 Ivacaftor (oral route) - Side effects & dosage - Mayo Clinic side effects oral route dosage mayo https://adisinsight.springer.com/drugsafety/803302730?error=cookies_not_supported&code=d97ed584-0dfc-41e2-8a9c-90e99ac4c794 Ivacaftor/lumacaftor/voriconazole - AdisInsight A 32-year-old man developed hallucinations during treatment with voriconazole and a 40-year-old man developed chest tightness during treatment with voriconazole adisinsight https://profiles.wustl.edu/en/publications/the-impact-of-elexacaftortezacaftorivacaftor-on-body-composition-/ The impact of elexacaftor/tezacaftor/ivacaftor on body composition in a small cohort of youth with... https://pubmed.ncbi.nlm.nih.gov/23276841/ Change in sweat chloride as a clinical end point in cystic fibrosis clinical trials: the ivacaftor... Cystic fibrosis (CF) is a life-shortening inherited disease caused by mutations in the CF transmembrane conductance regulator gene (CFTR), which encodes for... https://pubmed.ncbi.nlm.nih.gov/39785291/ Introduction of Ivacaftor/Lumacaftor in Children With Cystic Fibrosis Homozygous for F508del in the... Lum/iva was generally well tolerated in a real-life, nationwide pediatric cohort. The efficacy of lum/iva was comparable to phase 3 studies in children. LCI... https://www.research.ed.ac.uk/en/publications/assessment-of-clinical-response-to-ivacaftor-with-lung-clearance-/fingerprints/?sortBy=alphabetically Assessment of clinical response to ivacaftor with lung clearance index in cystic fibrosis patients... https://pmc.ncbi.nlm.nih.gov/articles/PMC12418867/ Elexacaftor-tezacaftor-ivacaftor in people with cystic fibrosis harbouring two CFTR Class I... The European Medicines Agency has recently expanded the label of elexacaftor-tezacaftor-ivacaftor (ETI) to all people with cystic fibrosis (pwCF) aged 2 years... https://medlineplus.gov/druginfo/meds/a619061.html Elexacaftor, Tezacaftor, and Ivacaftor: MedlinePlus Drug Information Elexacaftor, Tezacaftor, and Ivacaftor: learn about side effects, dosage, special precautions, and more on MedlinePlus medlineplus drug information https://adisinsight.springer.com/drugsafety/803928834?error=cookies_not_supported&code=3937cca7-a3e6-4037-b3e8-5c10545c8663 Ivacaftor/Lumacaftor - AdisInsight Patients [ages and sexes not stated] with cystic fibrosis receiving lumacaftor/ivacaftor [dose, route and duration not stated] were identified in a adisinsight https://pubchem.ncbi.nlm.nih.gov/compound/Elexacaftor_-ivacaftor_-tezacaftor_-ivacaftor Elexacaftor, ivacaftor, tezacaftor; ivacaftor - PubChem Elexacaftor, ivacaftor, tezacaftor; ivacaftor chemical information summary. pubchem https://adisinsight.springer.com/drugsafety/803923782?error=cookies_not_supported&code=d7fdc2e6-2985-4c7e-a148-0f0950c383fb Elexacaftor/Ivacaftor/Tezacaftor - AdisInsight Two children with cystic fibrosis developed hyperbilirubinaemia during treatment with elexacaftor, tezacaftor and ivacaftor. Both children, who had a history of adisinsight