https://www.verywellhealth.com/methotrexate-interactions-5112866
Methotrexate is the first-line recommended treatment for rheumatoid arthritis. However, it may interact with other medications.
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https://www.chroniclelive.co.uk/news/uk-news/nhs-methotrexate-warning-signs-mean-33166551
Jan 5, 2026 - Methotrexate is often the first medication prescribed for rheumatoid arthritis, but the NHS warns of serious side effects requiring urgent medical attention
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https://www.verywellhealth.com/methotrexate-side-effects-weight-gain-5112589
The rheumatoid arthritis drug methotrexate may lead to weight gain in some individuals and may be a sign of a serious side effect.
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https://www.leeds-live.co.uk/news/uk-world-news/nhs-methotrexate-warning-signs-mean-33162405
Methotrexate is usually the first medicine given for rheumatoid arthritis
warning signsnhsmethotrexatemeancall