mitophagy - Robuta Search

https://spiral.imperial.ac.uk/entities/publication/ef845e70-72ff-498b-bba7-d88a37a873d8 DRP1 levels determine the apoptotic threshold during embryonic differentiation through a mitophagy... The changes that drive differentiation facilitate the emergence of abnormal cells that need to be removed before they contribute to further development or the... https://medicine.uky.edu/centers/cvrc/events/tbd-2024-01-12t13-12-06 | "Mitophagy, Sex and the Gut Microbiome: Potential Roles in the Formation of Aortic Aneurysms" |... the gut microbiome https://cordis.europa.eu/project/id/101062916/pl In vitro reconstitution of the initiation of mitophagosome formation | Mitophagy | Projekt | Arkusz... Mitophagy is a tightly controlled process in which dysfunctional mitochondria are isolated and selectively degraded by autophagy. Many cell types critically... in vitro of the reconstitution https://profiles.wustl.edu/en/publications/coordinating-bnip3nix-mediated-mitophagy-in-space-and-time/fingerprints/ Coordinating BNIP3/NIX-mediated mitophagy in space and time - Fingerprint - WashU Research Profiles space and time https://dukespace.lib.duke.edu/items/b0f05f70-b50b-47e3-bcdb-47d6e312f1a1/full Inhibition of Sphingosine Kinase 2 Results in PARK2-Mediated Mitophagy and Induces Apoptosis in... Mitophagy plays an important role in maintaining mitochondrial homeostasis by clearing damaged mitochondria. Sphingosine kinase 2 (SK2), a type of sphingosine... https://pmc.ncbi.nlm.nih.gov/articles/PMC13006738/ GDF11 activates AMPK-dependent mitophagy to drive osteogenic differentiation of rat bone marrow... Background: Growth differentiation factor 11 (GDF11) has emerged as a potential regulator of bone regeneration; however, the molecular mechanisms through which... https://data.mendeley.com/datasets/83vvm47z2f/1 TEMs for the qualitative assessment of mitophagy in LHON cells - Mendeley Data Qualitative TEM mitophagy activity assessment on LHON 3460 fibroblasts (mito=mitochondria; AV=autophagy vacuoles; Arrow= autophagy vacuole membrane) (A). TEMs... for the https://pubmed.ncbi.nlm.nih.gov/38932521/?dopt=Abstract FoxG1/BNIP3 axis promotes mitophagy and blunts cisplatin resistance in osteosarcoma Cisplatin (CDDP) is a commonly used chemotherapeutic for osteosarcoma (OS) patients, and drug resistance remains as a major hurdle to undermine the treatment... axis promotes mitophagy https://pubmed.ncbi.nlm.nih.gov/31366282/ ESCRT-mediated phagophore sealing during mitophagy Inactivation of the endosomal sorting complex required for transport (ESCRT) machinery has been reported to cause autophagic defects, but the exact functions... mediated sealing mitophagy https://pubmed.ncbi.nlm.nih.gov/37627228/ Transcriptome Highlights Cannabinol Modulation of Mitophagy in a Parkinson's Disease In Vitro Model Parkinson's disease (PD) is a neurodegenerative disorder characterized by the loss of dopaminergic neurons in the substantia nigra and the accumulation of... https://pubmed.ncbi.nlm.nih.gov/38396029/ Gonococcal OMV-delivered PorB induces epithelial cell mitophagy The bacterial pathogen Neisseria gonorrhoeae is able to invade epithelial cells and survive intracellularly. During this process, it secretes outer membrane... omv delivered porb epithelial cell https://ub01.uni-tuebingen.de/xmlui/handle/10900/136757 Temporal analysis of parkin-dependent mitophagy using mass spectrometry-based proteomics mass spectrometry temporal analysis parkin dependent https://pubmed.ncbi.nlm.nih.gov/28465321/ Programmed mitophagy is essential for the glycolytic switch during cell differentiation Retinal ganglion cells (RGCs) are the sole projecting neurons of the retina and their axons form the optic nerve. Here, we show that embryogenesis-associated... for the programmed mitophagy essential https://pmc.ncbi.nlm.nih.gov/articles/PMC3630798/ Mitophagy: mechanisms, pathophysiological roles, and analysis - PMC Mitochondria are essential organelles that regulate cellular energy homeostasis and cell death. The removal of damaged mitochondria through autophagy, a... mitophagy mechanisms roles analysis pmc https://pubmed.ncbi.nlm.nih.gov/41904174/ Cardiomyocyte-derived GPX4 stabilizes BNIP3 to facilitate mitophagy and mitigate myocardial... GPX4 is a crucial regulator of ferroptosis, yet its role in mitochondrial dysfunction during myocardial ischemia/reperfusion injury (MI/RI) is unclear. This... cardiomyocyte derived https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2023.1117297/full Frontiers | Gene signature and prediction model of the mitophagy-associated immune microenvironment... BackgroundRenal ischemia-reperfusion injury (IRI) is an inevitable problem during kidney transplantation. Mitophagy, ferroptosis, and the associated immune m... prediction model https://experts.colorado.edu/display/pubid_254927 The plant triterpenoid celastrol blocks PINK1-dependent mitophagy by disrupting PINK1's association... the plant https://data.mendeley.com/datasets/2r5r5t8j5k/1 Mitochondrial fumarate inhibits Parkin-mediated mitophagy - Mendeley Data LC-MS/MS raw spectra and processed quantification data are presented in Fig. S11A and Fig. S2F mitochondrial fumarate parkin mediated mitophagy https://researchfestival.nih.gov/2018/posters/hsp90-involved-mitochondrial-quality-control-through-mitophagy-and Hsp90 involved in mitochondrial quality control through mitophagy and fusion/fission pathways | NIH... https://research.birmingham.ac.uk/en/publications/the-ros-mitophagy-signalling-pathway-regulates-liver-endothelial-/ The ROS-Mitophagy Signalling Pathway regulates liver endothelial cell survival during... ros mitophagy signalling pathway https://cordis.europa.eu/project/id/101062916/it In vitro reconstitution of the initiation of mitophagosome formation | Mitophagy | Progetto |... Mitophagy is a tightly controlled process in which dysfunctional mitochondria are isolated and selectively degraded by autophagy. Many cell types critically... in vitro of the reconstitution initiation formation https://pubmed.ncbi.nlm.nih.gov/40669210/ POLR1A inhibits ferroptosis by regulating TFAM-mediated mitophagy and iron homeostasis Evasion of programmed cell death (PCD) is a hallmark of cancer, yet the mechanisms underlying resistance to ferroptosis - an iron-dependent form of PCD... ferroptosis regulating https://www.mdpi.com/1999-4915/13/9/1845 Nonstructural Protein NS1 of Influenza Virus Disrupts Mitochondrial Dynamics and Enhances Mitophagy... Nonstructural protein 1 (NS1) of influenza virus (IFV) is essential for evading interferon (IFN)-mediated antiviral responses, thereby contributing to the... influenza virus https://pubmed.ncbi.nlm.nih.gov/27488107/ Roles of mitophagy in cellular physiology and development The autophagic degradation of mitochondria, or mitophagy, has been shown to occur in eukaryotic cells under various physiological conditions. Broadly, these... roles mitophagy cellular physiology development https://pubmed.ncbi.nlm.nih.gov/39725191/ Urolithin A attenuates Doxorubicin-induced cardiotoxicity by enhancing PINK1-regulated mitophagy... Doxorubicin (Dox) is a widely used antineoplastics although its clinical usage is greatly limited by its cardiotoxicity. Several studies have depicted an... urolithin a doxorubicin induced https://www.mrc-mbu.cam.ac.uk/research-groups/whitworth-group/mechanisms-mitophagy-and-pink1parkin-function Mechanisms of mitophagy and PINK1/Parkin function | MRC Mitochondrial Biology Unit MECHANISMS OF MITOPHAGY AND PINK1/PARKIN FUNCTION 1.1.mitophagy.png PINK1 and Parkin (PRKN), two genes linked to Parkinson's disease, have been strongly linked... mechanisms mitophagy https://pubmed.ncbi.nlm.nih.gov/24838945/ Tor and the Sin3-Rpd3 complex regulate expression of the mitophagy receptor protein Atg32 in yeast When mitophagy is induced in Saccharomyces cerevisiae, the mitochondrial outer membrane protein ScAtg32 interacts with the cytosolic adaptor protein ScAtg11.... https://vivo.colorado.edu/display/meshid_G04.011.937 Autophagy - Mitophagy | CU Experts | CU Boulder autophagy mitophagy cu experts boulder https://pubmed.ncbi.nlm.nih.gov/40604870/?dopt=Abstract SHMT2 overexpression improves glaucoma by enhancing mitophagy in retinal ganglion cells through... This study confirmed that SHMT2 overexpression alleviated glaucoma by enhancing mitophagy in RGCs through the upregulation of PINK1 phosphorylation, suggesting... https://pubmed.ncbi.nlm.nih.gov/39559367/ Single-cell sequencing unveils mitophagy-related prognostic model for triple-negative breast cancer The mitophagy-related prognostic model offers a novel method for predicting outcomes in TNBC patients and highlights the role of mitophagy in influencing the... single cell sequencing https://pubmed.ncbi.nlm.nih.gov/38476889/?dopt=Abstract Mitochondrial calcium uniporter promotes mitophagy by regulating the PINK1/Parkin pathway in... The mitochondrial calcium uniporter (MCU) is a major protein for the uptake of mitochondrial calcium to regulate intracellular energy metabolism, including... https://pubmed.ncbi.nlm.nih.gov/39811672/?dopt=Abstract ZFAND6 promotes TRAF2-dependent mitophagy to restrain cGAS-STING signaling ZFAND6 is a zinc finger protein that interacts with TNF receptor-associated factor 2 (TRAF2) and polyubiquitin chains and has been linked to tumor necrosis... promotes dependent mitophagy restrain cgas https://pubmed.ncbi.nlm.nih.gov/38753870/ Urolithin A improves Alzheimer's disease cognition and restores mitophagy and lysosomal functions Long-term urolithin A (UA) treatment improved learning, memory, and olfactory function in Alzheimer's disease (AD) mice. UA restored lysosomal functions in... urolithin a https://www.frontiersin.org/journals/cellular-neuroscience/articles/10.3389/fncel.2016.00076/full Frontiers | Flow Cytometry-Based Assessment of Mitophagy Using MitoTracker flow cytometry frontiers based assessment mitophagy https://pubmed.ncbi.nlm.nih.gov/36880403/?dopt=Abstract Sema3A alleviates viral myocarditis by modulating SIRT1 to regulate cardiomyocyte mitophagy Viral myocarditis (VMC) is a common myocardial inflammatory disease characterized by inflammatory cell infiltration and cardiomyocyte necrosis. Sema3A was... viral myocarditis https://pubmed.ncbi.nlm.nih.gov/39669425/?dopt=Abstract Phosphorylation of Optineurin by protein kinase D regulates Parkin-dependent mitophagy Degradation of damaged mitochondria, a process called mitophagy, plays a role in mitochondrial quality control and its dysfunction has been linked to... protein kinase d phosphorylation https://scholars.lib.ntu.edu.tw/entities/project/4686d628-9b8b-49f7-9c18-575d718ef8fb Modulation of Hypoxia-Induced Osteoblast Necroptosis and Mitophagy by Simvastatin and Its... modulation hypoxia induced osteoblast