Robuta

https://www.fredhutch.org/en/news/spotlight/2024/07/bs-strong-heliyon.html Two steps forward, one step back for targeting NKG2D in cancer treatment - Fred Hutch Jul 24, 2024 - Engineered NKG2D decoys have promising initial activity yet fall short of showing clinical efficacy two steps forward https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2017.00179/full Frontiers | MICA and NKG2D: Is There an Impact on Kidney Transplant Outcome? This paper aims to present an overview of MICA and NKG2D genetic and functional interactions and their impact on kidney transplant outcome. Organ transplant... is there https://www.jci.org/articles/view/142842 JCI - Upregulation of NKG2D ligands impairs hematopoietic stem cell function in Fanconi anemia hematopoietic stem cell https://elifesciences.org/articles/30881v1/figures Figures and data in Endothelial cells express NKG2D ligands and desensitize anti-tumor NK responses... https://www.ncbi.nlm.nih.gov/Structure/pdb/8SE5 8SE5: NKG2D complexed with inhibitor 14 NKG2-D type II integral membrane... nkg2d inhibitor 14 https://www.frontiersin.org/journals/oncology/articles/10.3389/fonc.2022.1009089/full Frontiers | Radiosensitization effect by HDAC inhibition improves NKG2D-dependent natural killer... Background: Hepatocellular carcinoma (HCC) is one of the leading causes of cancer-related death worldwide. Radiotherapy (RT) controls HCC unsatisfactorily an... hdac inhibition frontiers effect https://elifesciences.org/articles/14749 A Herpesviral induction of RAE-1 NKG2D ligand expression occurs through release of HDAC mediated... Viral infection can induce NKG2D ligand expression through the action of virally encoded histone deacetylase (HDAC) inhibitors, which release HDAC mediated... https://www.omicsonline.org/open-access/the-impact-of-sevoflurane-on-nkg2dmediated-cancer-immunosurveillance-and-its-implications-for-future-research.pdf The Impact of Sevoflurane on NKG2D-Mediated Cancer Immunosurveillance and its Implications for... https://www.jci.org/articles/view/43961 JCI - Recombinant mouse cytomegalovirus expressing a ligand for the NKG2D receptor is attenuated... https://elifesciences.org/articles/30881 Endothelial cells express NKG2D ligands and desensitize antitumor NK responses | eLife Antitumor (natural killer) NK cell responses are negatively regulated by interactions between NK cells and endogenous NKG2D ligands constitutively expressed on... endothelial cells express nkg2d ligands