Robuta

https://elifesciences.org/reviewed-preprints/101973v2 ORMDL3 restrains type-I interferon signaling and anti-tumor immunity by promoting RIG-I degradation https://www.rcsb.org/structure/7CQI RCSB PDB - 7CQI: Cryo-EM structure of the substrate-bound SPT-ORMDL3 complex Cryo-EM structure of the substrate-bound SPT-ORMDL3 complex https://www.ncbi.nlm.nih.gov/gene/94103 ORMDL3 ORMDL sphingolipid biosynthesis regulator 3 [Homo sapiens (human)] - Gene - NCBI sphingolipid biosynthesis homo sapiens human gene ormdl3 regulator https://elifesciences.org/articles/101973 ORMDL3 restrains type I interferon signaling and anti-tumor immunity by promoting RIG-I degradation... ORMDL3 promotes RIG-I degradation to suppress type I interferon signaling pathway and antiviral immune response, highlighting ORMDL3 as a potential therapeutic... https://www.rcsb.org/structure/6M4O RCSB PDB - 6M4O: Cryo-EM structure of the monomeric SPT-ORMDL3 complex Cryo-EM structure of the monomeric SPT-ORMDL3 complex rcsb pdb cryo em