https://tobias-lib.ub.uni-tuebingen.de/xmlui/handle/10900/36751
The role of PINK1 and Parkin in the autophagic degradation process of depolarized mitochondria
the role
https://severus.dbmi.pitt.edu/wiki-MPM/index.php/pair/view/9532/65018
BAG2 and PINK1 - Wiki-MPM
Wiki-wiki: a wiki resource centered on human protein-protein interactions
wikimpm
https://scholars.lib.ntu.edu.tw/entities/project/b750be03-08d8-46e5-aae2-84fa09531fd9
Study of the Mechanisms for Neuronal Apoptosis Induced by the PINK1 Mutation
of thestudymechanisms
https://pubchem.ncbi.nlm.nih.gov/bioassay/1828761
AID 1828761 - Activation of PINK1 in human HeLa MKYP PINK1-knock out cells at 3.125 to 6.25 uM...
BioAssay record AID 1828761 submitted by ChEMBL: Activation of PINK1 in human HeLa MKYP PINK1-knock out cells at 3.125 to 6.25 uM assessed as reduction in...
https://biology.washington.edu/node/2267
PINK1-Parkin pathway activity is regulated by degradation of PINK1 in the mitochondrial matrix. |...
Loss-of-function mutations in PINK1, which encodes a mitochondrially targeted serine/threonine kinase, result in an early-onset heritable form of Parkinson's...
https://pubmed.ncbi.nlm.nih.gov/38293125/?dopt=Abstract
Development and characterization of phospho-ubiquitin antibodies to monitor PINK1-PRKN signaling in...
The selective removal of dysfunctional mitochondria, a process termed mitophagy, is critical for cellular health and impairments have been linked to aging,...
https://tobias-lib.ub.uni-tuebingen.de/xmlui/handle/10900/129484
The role of the individual TOM subunits in the association of PINK1 with depolarized mitochondria
the role
https://experts.colorado.edu/display/pubid_254927
The plant triterpenoid celastrol blocks PINK1-dependent mitophagy by disrupting PINK1's association...
the plant
https://pubmed.ncbi.nlm.nih.gov/39725191/
Urolithin A attenuates Doxorubicin-induced cardiotoxicity by enhancing PINK1-regulated mitophagy...
Doxorubicin (Dox) is a widely used antineoplastics although its clinical usage is greatly limited by its cardiotoxicity. Several studies have depicted an...
urolithin adoxorubicininduced
https://www.mrc-mbu.cam.ac.uk/research-groups/whitworth-group/mechanisms-mitophagy-and-pink1parkin-function
Mechanisms of mitophagy and PINK1/Parkin function | MRC Mitochondrial Biology Unit
MECHANISMS OF MITOPHAGY AND PINK1/PARKIN FUNCTION 1.1.mitophagy.png PINK1 and Parkin (PRKN), two genes linked to Parkinson's disease, have been strongly linked...
mechanismsmitophagy
https://data.mendeley.com/datasets/789652xcr3/1
PINK1/Parkin Influences Cell Cycle by Sequestering TBK1 at Damaged Mitochondria Inhibiting Mitosis...
This data is the western blot data for Sarraf, Sideris et al. "PINK1/Parkin Influences Cell Cycle by Sequestering TBK1 at Damaged Mitochondria Inhibiting...
https://brainandmind.weill.cornell.edu/parkin-and-pink1-patient-ipsc-derived-midbrain-dopamine-neurons-exhibit-mitochondrial-dysfunction
Parkin and PINK1 Patient iPSC-Derived Midbrain Dopamine Neurons Exhibit Mitochondrial Dysfunction...
https://bio.as.uky.edu/bibcite/reference/21050
Quantitative expression proteomics and phosphoproteomics profile of brain from PINK1 knockout mice:...
https://pubmed.ncbi.nlm.nih.gov/36478228/
Mitochondrial DNA heteroplasmy distinguishes disease manifestation in PINK1/PRKN-linked Parkinson's...
Biallelic mutations in PINK1/PRKN cause recessive Parkinson's disease. Given the established role of PINK1/Parkin in regulating mitochondrial dynamics, we...
mitochondrial dna
https://pubmed.ncbi.nlm.nih.gov/16672980/?dopt=Abstract
Mitochondrial dysfunction in Drosophila PINK1 mutants is complemented by parkin
Autosomal recessive juvenile parkinsonism (AR-JP) is an early-onset form of Parkinson's disease characterized by motor disturbances and dopaminergic...
mitochondrial dysfunctiondrosophilamutantsparkin
https://pubmed.ncbi.nlm.nih.gov/36305379/
Gene-based burden analysis of damaging private variants in PRKN, PARK7 and PINK1 in Parkinson's...
Recessive mutations in PRKN, PARK7, and PINK1 are established causes of early-onset Parkinson's disease (EOPD). Previous studies have interrogated the role of...
https://pubmed.ncbi.nlm.nih.gov/38802071/?dopt=Abstract
Development and characterization of phospho-ubiquitin antibodies to monitor PINK1-PRKN signaling in...
The selective removal of dysfunctional mitochondria, a process termed mitophagy, is critical for cellular health and impairments have been linked to aging,...
https://pubmed.ncbi.nlm.nih.gov/38476889/?dopt=Abstract
Mitochondrial calcium uniporter promotes mitophagy by regulating the PINK1/Parkin pathway in...
The mitochondrial calcium uniporter (MCU) is a major protein for the uptake of mitochondrial calcium to regulate intracellular energy metabolism, including...