Robuta

Mitochondrial dysfunction in health and disease

A significant unresolved question is how vitamin A deprivation causes, and why retinoic acid fails to reverse, immunodeficiency. When depleted of vitamin A, T...

Mitochondrial dysfunction is the root cause of many diseases that are bewildering in their variety and complexity. They include rare genetic disorders in...

Our novel in vivo model of direct placental mTOR-driven FGR provides strong evidence linking placental dysfunction and amino acid transport to proper...

Isoniazid (INH) continues to be a sheet anchor in treatment of tuberculosis, however its chronic administration is known to cause hepatotoxicity through a...

Chronic Lung Allograft Dysfunction (CLAD) is a life-threatening complication that limits the long-term survival of lung transplantation patients. Early...

Experiment is an online platform for funding and sharing scientific discoveries. Push the boundaries of knowledge in biology, chemistry, medicine, physics,...

In this video, Dr. Seheult of MedCram discusses patients with long COVID and how mitochondrial dysfunction of fat metabolism may play a role.

Sporadic inclusion body myositis (sIBM) is the most common idiopathic inflammatory myopathy, and several reports have suggested that mitochondrial...

Both inflammation, autoimmunity, and several other malignancies, share the symptom of tissue damage that perturbs the body's homeostasis and leads to disease....

New papers reveal how mitochondrial defects lead to accelerated aging as demonstrated by shorter telomeres and other biomarkers of aging.

Mitochondrial dysfunction is a characteristic trait of human and rodent obesity, insulin resistance and fatty liver disease. Here we show that high-fat diet...