polygenic - Robuta Search

https://research.vu.nl/en/publications/applying-polygenic-risk-scoring-for-psychiatric-disorders-to-a-la/ Applying polygenic risk scoring for psychiatric disorders to a large family with bipolar disorder... https://research.rug.nl/en/publications/bayesian-inference-analyses-of-the-polygenic-architecture-of-rheu/ Bayesian inference analyses of the polygenic architecture of rheumatoid arthritis - the University... bayesian inference of the rheumatoid arthritis analyses polygenic https://edrn.cancer.gov/data-and-resources/publications/39763728-pathway-polygenic-risk-scores-pprs-for-the-analysis-of-gene-environment-interaction/ Pathway Polygenic Risk Scores (pPRS) for the Analysis of Gene-environment Interaction. This is a publication by a member of the Early Detection Research Network. polygenic risk scores for the https://infoproc.blogspot.com/2019/08/polygenic-architecture-and-risk.html Information Processing: Polygenic Architecture and Risk Prediction for 14 Cancers and Schizophrenia Two recent papers on polygenic risk prediction. As I've emphasized before, these predictors already have real clinical utility but they will... information processing risk prediction polygenic architecture https://pubmed.ncbi.nlm.nih.gov/38249435/?dopt=Abstract Polygenic Scores in Developmental Psychology: Invite Genetics In, Leave Biodeterminism Behind Polygenic scores offer developmental psychologists new methods for integrating genetic information into research on how people change and develop across the... polygenic scores developmental psychology invite genetics leave https://blogs.bmj.com/jmg/2022/09/23/clinical-applicability-of-the-polygenic-risk-score-for-breast-cancer-risk-prediction-in-familial-cases/ Clinical applicability of the Polygenic Risk Score for breast cancer risk prediction in familial... Feb 23, 2026 - A 313-variant-based polygenic risk score (PRS) is shown to stratify women from breast cancer families into different clinically relevant risk categories.... https://pubmed.ncbi.nlm.nih.gov/26695942/ Polygenic risk of ischemic stroke is associated with cognitive ability The findings from this study indicate that even in the absence of stroke, being at high polygenic risk of ischemic stroke is associated with lower cognitive... is associated with ischemic stroke polygenic risk cognitive https://boris-portal.unibe.ch/entities/publication/a05ae022-7494-4398-8836-22e32eb5bf56 Association of a Polygenic Risk Score with Osteoporosis in People Living with HIV: The Swiss HIV... BACKGROUND Bone mineral density (BMD) loss may be accelerated in people with HIV (PLWH). It is unknown whether an individual polygenic risk score (PRS) is... https://open.library.emory.edu/concern/publications/0ddeeee1-7df0-4134-9e11-3b4ca1d03ab7?locale=en A multi-ancestry polygenic risk score improves risk prediction for coronary artery disease |... A multi-ancestry polygenic risk score improves risk prediction for coronary artery disease risk score https://www.repository.cam.ac.uk/items/8e3fee58-2486-4376-a68f-f11d7e24328a Causation and familial confounding as explanations for the associations of polygenic risk scores... A polygenic risk score (PRS) combines the associations of multiple genetic variants that could be due to direct causal effects, indirect genetic effects, or... https://pmc.ncbi.nlm.nih.gov/articles/PMC11686414/ Alcohol Use Disorder Polygenic Score Compared With Family History and ADH1B - PMC Can a polygenic score (PGS) be used to evaluate the risk of alcohol use disorder (AUD) among populations of European ancestry? In this genetic association... alcohol use disorder https://pubmed.ncbi.nlm.nih.gov/31492941/ A polygenic resilience score moderates the genetic risk for schizophrenia Based on the discovery by the Resilience Project (Chen R. et al. Nat Biotechnol 34:531-538, 2016) of rare variants that confer resistance to Mendelian disease,... polygenic resilience score moderates genetic https://experts.umn.edu/en/publications/temporally-resolved-growth-patterns-reveal-novel-information-abou/ Temporally resolved growth patterns reveal novel information about the polygenic nature of complex... https://genomisaur.com/ Polygenic Risk Score & Preconception Genetic Reports | Genomisaur Polygenic risk scores for 71 conditions and preconception carrier screening from your existing 23andMe, AncestryDNA, or MyHeritage data. Results in ~20... risk score polygenic preconception genetic reports https://digital.library.adelaide.edu.au/items/c6c7387a-638f-4b86-9c60-120b24f8e8db Genetic correlations of polygenic disease traits: from theory to practice The genetic correlation describes the genetic relationship between two traits and can contribute to a better understanding of the shared biological pathways... genetic correlations polygenic disease traits https://infoproc.blogspot.com/2021/07/polygenic-embryo-screening-comments-on.html?m=0 Information Processing: Polygenic Embryo Screening: comments on Carmi et al. and Visscher et al. In this post I discuss some recent papers on disease risk reduction from polygenic screening of embryos in IVF (PGT-P). I will focus on the ... information processing https://pubmed.ncbi.nlm.nih.gov/35513726/ Polygenic risk scores for CARDINAL study The Cardiometabolic Disorders in African-Ancestry Populations (CARDINAL) study site is a well-powered, first-of-its-kind resource for developing, refining and... polygenic risk scores cardinal study https://about.uq.edu.au/experts/project/65092 Using risk profiles to overcome challenges in incorporating polygenic risk scores into clinical... risk profiles https://id.wiktionary.org/wiki/polygenic_character polygenic character - Wikikamus bahasa Indonesia polygenic character wikikamus bahasa indonesia https://scholarworks.indianapolis.iu.edu/items/58fef03c-f582-43c3-a62e-f7fbd044de7a Explicit Modeling of Ancestry Improves Polygenic Risk Scores and BLUP Prediction Polygenic prediction using genome-wide SNPs can provide high prediction accuracy for complex traits. Here, we investigate the question of how to account for... polygenic risk scores explicit modeling ancestry improves https://researchcollaborations.elsevier.com/en/publications/prediction-of-individual-genetic-risk-to-prostate-cancer-using-a-/ Prediction of individual genetic risk to prostate cancer using a polygenic score - Elsevier's... https://scholars.cityu.edu.hk/en/publications/intrinsic-capacity-polygenic-risk-score-iapoe-igenotype-and-risk-/ Intrinsic Capacity, Polygenic Risk Score, APOE Genotype, and Risk of Dementia: A Prospective... risk score apoe genotype https://elementolab.weill.cornell.edu/publications/utilization-serum-metabolomics-and-polygenic-risk-scores-novel-risk-stratification-tool Utilization of Serum Metabolomics and Polygenic Risk Scores in a Novel Risk Stratification Tool for... https://www.frontiersin.org/journals/genetics/articles/10.3389/fgene.2025.1538975/full Frontiers | Development and validation of a polygenic risk score for height in a Greek cohort:... Human height is a highly heritable trait. Genome-wide association studies have identified thousands of genetic variants linked to height, some of which exhib... https://hscrb.harvard.edu/publication/problems-with-using-polygenic-scores-to-select-embryos-n-engl-j-med-2021-07-01-385178-86/ Problems with Using Polygenic Scores to Select Embryos. N Engl J Med. 2021 07 01; 385(1):78-86. |... https://professional.heart.org/en/science-news/polygenic-risk-scores-for-cardiovascular-disease/top-things-to-know Polygenic Risk Scores for CVD - Professional Heart Daily | American Heart Association polygenic risk scores professional heart daily cvd american association https://sagesociology.libsyn.com/sociological-methodology-polygenic-indices-aka-polygenic-scores-in-social-science-a-guide-for-interpretation-and-evaluation Sage Sociology: Sociological Methodology - Polygenic Indices (aka Polygenic Scores) in Social... Author Callie Burt discusses her article, "Polygenic Indices (aka Polygenic Scores) in Social Science: A Guide for Interpretation and Evaluation," published in... sage sociology sociological methodology polygenic https://pmc.ncbi.nlm.nih.gov/articles/PMC11976246/ Understanding the potential contribution of polygenic risk scores to the prediction of gestational... British Pakistani and Bangladeshi (BPB) women have disproportionately high rates of gestational diabetes mellitus (GDM), with prevalence estimates up to three... polygenic risk scores the potential understanding contribution https://research-portal.st-andrews.ac.uk/en/datasets/risk-variants-and-polygenic-architecture-of-disruptive-behavior-d/ Risk variants and polygenic architecture of disruptive behavior disorders in the context of... disruptive behavior disorders https://profiles.wustl.edu/en/publications/polygenic-risk-prediction-why-and-when-out-of-sample-prediction-r/ Polygenic risk prediction: why and when out-of-sample prediction R2 can exceed SNP-based... https://research.monash.edu/en/publications/polygenic-risk-scores-are-associated-with-atrial-electrophysiolog/projects/ Polygenic risk scores are associated with atrial electrophysiologic substrate abnormalities and... polygenic risk scores associated with https://tobias-lib.ub.uni-tuebingen.de/xmlui/handle/10900/115176 Breast Cancer Polygenic Risk Score and Contralateral Breast Cancer Risk breast cancer risk score polygenic https://pubmed.ncbi.nlm.nih.gov/33257657/ Polygenic scores for schizophrenia and general cognitive ability: associations with six cognitive... Cognitive impairments are considered core features in schizophrenia and other psychotic disorders. Cognitive impairments are, to a lesser degree, also... polygenic scores cognitive ability schizophrenia https://pure.lib.usf.edu/en/publications/eye-tracking-indices-of-attentional-bias-in-children-of-depressed-2/ Eye tracking indices of attentional bias in children of depressed mothers: Polygenic influences... eye tracking attentional bias https://infoproc.blogspot.com/2022/10/times-of-israel-on-polygenic-embryo.html?m=0 Information Processing: Times of Israel on Polygenic Embryo Screening This is a very nice article on polygenic embryo screening and its prospects in Israel. Worth reading in full. Leading statistical genetici... times of israel information processing polygenic embryo screening https://digital.library.adelaide.edu.au/items/a6118821-3509-47c0-93a6-65c52f8452d5 The SCRIPT trial: study protocol for a randomised controlled trial of a polygenic risk score to... Background: Polygenic risk scores (PRSs) can predict the risk of colorectal cancer (CRC) and target screening more precisely than current guidelines using age... https://infoscience.epfl.ch/entities/publication/13716411-09fb-4bfd-969f-ea9888c13c4a Polygenic variants in DNA repair genes are associated with neurodevelopmental disorders, regression... Purpose Developmental regression, characterized by the loss of acquired milestones, occurs in some individuals with neurodevelopmental disorders (NDDs); yet,... dna repair https://www.research.ed.ac.uk/en/publications/pathway-based-polygenic-risk-scores-for-schizophrenia-and-associa/ Pathway-based polygenic risk scores for schizophrenia and associations with reported psychotic-like... polygenic risk scores https://elbiruniblogspotcom.blogspot.com/2014/08/rabbit-genome-analysis-reveals.html CIENCIASMEDICASNEWS: Rabbit genome analysis reveals a polygenic basis for phenotypic change during... Rabbit genome analysis reveals a polygenic basis for phenotypic change during domestication Rabbit Genome Provides Insight Into Genetics o... genome analysis https://hsrc.himmelfarb.gwu.edu/gwhpubs/5526/ "Polygenic Risk Is Associated With Long-Term Coronary Plaque Progressio" by Nick S. Nurmohamed,... BACKGROUND: The longitudinal relation between coronary artery disease (CAD) polygenic risk score (PRS) and long-term plaque progression and high-risk plaque... https://www.genome.gov/genetics-glossary/Polygenic-Trait Polygenic Trait A polygenic trait is one whose phenotype is influenced by more than one gene. polygenic trait https://research.vu.nl/en/publications/schizophrenia-and-bipolar-polygenic-risk-scores-in-relation-to-in/ Schizophrenia and Bipolar Polygenic Risk Scores in Relation to Intracranial Volume - Vrije... polygenic risk scores in relation to https://www.igb.illinois.edu/wheeler/article/polygenic-risk-scores-need-better-regulation-study-argues Polygenic risk scores need better regulation, study argues | Carl R. Woese Institute for Genomic... polygenic risk scores https://open.bu.edu/items/71428522-dd27-4fcb-87a2-3b409a6168d2 Family history of non-affective psychosis is related to polygenic risk scores in schizophrenia BACKGROUND: Polygenic risk scores (PRS) have emerged as a promising tool for predicting the risk of developing a variety of illnesses, including psychiatric... https://pmc.ncbi.nlm.nih.gov/articles/PMC7411027/ Sibling validation of polygenic risk scores and complex trait prediction - PMC We test 26 polygenic predictors using tens of thousands of genetic siblings from the UK Biobank (UKB), for whom we have SNP genotypes, health status, and... polygenic risk scores sibling validation https://collaborate.princeton.edu/en/publications/polygenic-scores-associated-with-educational-attainment-in-adults/ Polygenic scores associated with educational attainment in adults predict educational achievement... polygenic scores associated with educational attainment adults predict https://nij.ojp.gov/library/publications/syndrome-informed-phenotyping-identifies-polygenic-background-achondroplasia Syndrome-informed Phenotyping Identifies a Polygenic Background for Achondroplasia-like Facial... In this study, researchers use syndrome-informed phenotyping to identify a polygenic background for achondroplasia-like facial variation in the general... syndrome informed phenotyping identifies https://www.merriam-webster.com/dictionary/polygenic POLYGENIC Definition & Meaning - Merriam-Webster The meaning of POLYGENIC is of, relating to, mediated by, or constituting polygenes : involving two or more nonallelic genes collectively in determining... polygenic definition meaning merriam webster https://research.monash.edu/en/publications/polygenic-risk-score-improves-prostate-cancer-risk-prediction-res/ Polygenic risk score improves prostate cancer risk prediction: Results from the Stockholm-1 cohort... https://pubmed.ncbi.nlm.nih.gov/33771847/ The Shared Genetic Architectures Between Lung Cancer and Multiple Polygenic Phenotypes in... These findings provide new insights into the etiology of lung cancer by identifying traits that are genetically correlated with increased risk of lung cancer. lung cancer https://researchconnect.buffalo.edu/en/publications/african-specific-improvement-of-a-polygenic-hazard-score-for-age-/ African-specific improvement of a polygenic hazard score for age at diagnosis of prostate cancer -... https://ub01.uni-tuebingen.de/xmlui/handle/10900/91568?show=full Polygenic Load: Earlier Disease Onset but Similar Longitudinal Progression in Parkinson's Disease https://pubmed.ncbi.nlm.nih.gov/30770720/?dopt=Abstract Polygenic and sex specific architecture for two maturation traits in farmed Atlantic salmon The results extend earlier work and have implications for future applied breeding strategies to delay maturation in this important aquaculture species. https://digitalonehealth.csiro.au/tag/polygenic-risk/ Polygenic risk - Digital OneHealth polygenic risk digital onehealth https://impacts.ucar.edu/en/publications/rdaforest-identifying-environmental-drivers-of-polygenic-adaptati/ RDAforest: Identifying Environmental Drivers of Polygenic Adaptation - Impacts @ NSF NCAR and UCAR https://infoproc.blogspot.com/2020/03/within-family-validation-of-polygenic.html Information Processing: Within-Family Validation of Polygenic Risk Scores and Complex Trait... We examined the performance of disease risk and complex trait predictors using about 40k siblings in late adulthood. As the figures show, pr... polygenic risk scores information processing https://law.illinois.edu/new-co-authored-paper-from-sherkow-regulating-direct-to-consumer-polygenic-risk-scores/ New co-authored paper from Sherkow: "Regulating Direct-to-Consumer Polygenic Risk Scores" - College... Professor Jacob Sherkow has co-authored a paper, "Regulating Direct-to-Consumer Polygenic Risk Scores," that was published in JAMA. In the paper, the authors... https://ascvd-lipidology.knowledgehub.wiley.com/twelve-variants-polygenic-score-for-low-density-lipoprotein-cholesterol-distribution-in-a-large-cohort-of-patients-with-clinically-diagnosed-familial-hypercholesterolemia-with-or-without-causative-mut/ Twelve Variants Polygenic Score for Low-Density Lipoprotein Cholesterol Distribution in a Large... low density lipoprotein https://digital.library.adelaide.edu.au/items/f9f43e73-b320-4680-a659-18c7e8f7631b Socioeconomic disadvantage and polygenic risk of overweight in early and mid-life: a longitudinal... Background: We describe BMI by socioeconomic disadvantage and by polygenic risk in parallel cohorts of children and adults (their parents). We examine whether... https://pmc.ncbi.nlm.nih.gov/articles/PMC11465192/ Calibrated prediction intervals for polygenic scores across diverse contexts - PMC Polygenic scores (PGS) have emerged as the tool of choice for genomic prediction in a wide range of fields. We show that PGS performance varies broadly across... polygenic scores calibrated prediction intervals across https://pubmed.ncbi.nlm.nih.gov/39888077/ Reference-Based Standardization Approach Stabilizing Small Batch Risk Prediction via Polygenic Score The polygenic score (PGS) holds promise for motivating preventive behavioral changes. However, no clinically validated standardization methodology currently... small batch https://edrn.cancer.gov/data-and-resources/publications/41488031-applypolygenicscore-an-r-package-for-applying-polygenic-risk-score-models/ ApplyPolygenicScore: An R package for applying polygenic risk score models. This is a publication by a member of the Early Detection Research Network. r package risk score applying polygenic models https://openresearch.surrey.ac.uk/esploro/outputs/journalArticle/Systematic-Review-and-Meta-Analysis-Phenotypic-Correlates/99985666602346 Systematic Review and Meta-Analysis: Phenotypic Correlates of the Autism Polygenic Score -... systematic review meta analysis https://collaborate.princeton.edu/en/publications/gene-discovery-and-polygenic-prediction-from-a-genome-wide-associ-2/ Gene discovery and polygenic prediction from a genome-wide association study of educational... https://scholars.duke.edu/publication/1684914 Scholars@Duke publication: Associations between epilepsy-related polygenic risk and brain... scholars duke publication associations https://researchprofiles.ku.dk/da/publications/the-relationship-between-11-different-polygenic-longevity-scores-/ The relationship between 11 different polygenic longevity scores, parental lifespan, and disease... the relationship https://research-portal.st-andrews.ac.uk/en/publications/risk-variants-and-polygenic-architecture-of-disruptive-behavior-d/ Risk variants and polygenic architecture of disruptive behavior disorders in the context of... disruptive behavior disorders https://web.ub.edu/ca/web/facultat-biologia/w/polygenic-evidence-for-the-psychosis-continuum-insights-into-risk-resilience-and-biologically-informed-score-associations Polygenic evidence for the psychosis continuum: insights into risk, resilience, and... for the polygenic evidence psychosis https://fpg.unc.edu/publications/gender-differences-association-polygenic-risk-and-divergent-depression-trajectories-mid Gender Differences in the Association of Polygenic Risk and Divergent Depression Trajectories from... https://bioethics.iu.edu/events/noniuevents/incorporating-polygenic-risk-scores-and-social-determinants-of-health-across-populations.html Incorporating Polygenic Risk Scores and Social Determinants of Health Across Populations: Non-IU... Incorporating Polygenic Risk Scores and Social Determinants of Health Across Populations social determinants of health polygenic risk scores https://www.sciencedaily.com/releases/2021/06/210630173622.htm Report sounds alarm on efficacy, safety, ethics of embryo selection with polygenic scores |... A new report raises serious questions about the benefits, risks and ethics of a new service -- which the authors call 'embryo selection based on polygenic... https://fis.tu-dresden.de/portal/en/publications/limitations-in-nextgeneration-sequencingbased-genotyping-of-breast-cancer-polygenic-risk-score-loci(2f0a269f-ec74-4ab9-ad81-c3ac633a7ab6).html Limitations in next-generation sequencing-based genotyping of breast cancer polygenic risk score... next generation sequencing https://pubmed.ncbi.nlm.nih.gov/26430803/?dopt=Abstract Modeling Linkage Disequilibrium Increases Accuracy of Polygenic Risk Scores Polygenic risk scores have shown great promise in predicting complex disease risk and will become more accurate as training sample sizes increase. The standard... modeling linkage disequilibrium increases accuracy https://pmc.ncbi.nlm.nih.gov/articles/PMC11546823/ Polygenic risk for alcohol use disorder affects cellular responses to ethanol exposure in a human... Polygenic risk scores (PRSs) assess genetic susceptibility to alcohol use disorder (AUD), yet their molecular implications remain underexplored. Neuroimmune... https://kth.diva-portal.org/smash/record.jsf?pid=diva2:1981092 Leveraging Disease Relevant Transcriptomes From TOPMed LTRC Improves Polygenic Transcriptome Risk... leveraging disease relevant transcriptomes https://www.pgscatalog.org/ PGS Catalog - The Polygenic Score Catalog The Polygenic Score (PGS) Catalog is an open database of published PGS and the relevant metadata needed to apply and evaluate them correctly. pgs catalog polygenic score https://events.diabetes.org/p/s/type-1-diabetes-multiancestry-polygenic-score-t1d-maps-is-a-robust-predictor-of-type-1-diabetes-risk-across-diverse-populations-5658 Type 1 Diabetes Multiancestry Polygenic Score (T1D MAPS) Is a Robust Predictor of Type 1 Diabetes... https://uu.diva-portal.org/smash/record.jsf?pid=diva2%3A1895778 Deciphering Adult Autism : Exploring Polygenic Risk, Brain Structure, Well-being, Migraine, and... adult autism https://www.frontiersin.org/journals/psychiatry/articles/10.3389/fpsyt.2024.1275719/full Frontiers | Gut microbial diversity moderates polygenic risk of schizophrenia Background: Schizophrenia (SCZ) is a heritable disorder with a polygenic architecture, and gut microbiota seems to be involved in development and outcome. He... microbial diversity frontiers gut moderates polygenic https://researchportalplus.anu.edu.au/en/publications/using-polygenic-risk-scores-for-prioritizing-individuals-at-great/ Using Polygenic Risk Scores for Prioritizing Individuals at Greatest Need of a Cardiovascular... polygenic risk scores https://pubmed.ncbi.nlm.nih.gov/35324888/ Significant sparse polygenic risk scores across 813 traits in UK Biobank polygenic risk scores in uk significant sparse https://pubmed.ncbi.nlm.nih.gov/32649918/ Chronic obstructive pulmonary disease and related phenotypes: polygenic risk scores in... US National Institutes of Health, Wellcome Trust. polygenic risk scores pulmonary disease chronic https://pubmed.ncbi.nlm.nih.gov/30888520/ Genetic Mechanisms Highlight Shared Pathways for the Pathogenesis of Polygenic Type 1 Diabetes and... Genome-wide association studies have identified 57 genetic risk loci for type 1 diabetes. Progress has been made in unravelling the mechanistic effects of some... https://researchcollaborations.elsevier.com/en/publications/additional-snps-improve-risk-stratification-of-a-polygenic-hazard/ Additional SNPs improve risk stratification of a polygenic hazard score for prostate cancer -... https://tagteam.harvard.edu/hub_feeds/3661/feed_items/9104935/content TagTeam :: Identifying Rare Genetic Determinants for Improved Polygenic Risk Prediction of Bone... https://academiccommons.columbia.edu/doi/10.7916/g92r-1x46 Childhood maltreatment and health in the UK Biobank: triangulation of outcome-wide and polygenic... Background Childhood maltreatment is common globally and impacts morbidity, mortality, and well-being. Our understanding of its impact is constrained by key... in the uk https://researchcollaborations.elsevier.com/en/publications/the-effect-of-sample-size-on-polygenic-hazard-models-for-prostate/ The effect of sample size on polygenic hazard models for prostate cancer - Elsevier's Research... https://pubmed.ncbi.nlm.nih.gov/33594131/ Evidence for specificity of polygenic contributions to attainment in English, maths and science... How well one does at school is predictive of a wide range of important cognitive, socioeconomic, and health outcomes. The last few years have shown marked... https://ifp.nyu.edu/2017/open-access-journal-articles/mir-137-derived-polygenic-risk-effects-cognitive-performance-patients-schizophrenia-controls/ MiR-137-derived polygenic risk: effects on cognitive performance in patients with schizophrenia and... https://scholarworks.indianapolis.iu.edu/items/ac863aaf-1945-4660-b684-7021cb23bb69 The Impact of Peer Substance Use and Polygenic Risk on Trajectories of Heavy Episodic Drinking... BACKGROUND: Heavy episodic drinking is developmentally normative among adolescents and young adults, but is linked to adverse consequences in later life, such... https://infoproc.blogspot.com/2021/01/from-genotype-to-phenotype-polygenic.html Information Processing: From Genotype to Phenotype: polygenic prediction of complex human traits New paper, prepared for the book Genomic Prediction of Complex Traits , Springer Nature series Methods in Molecular Biology . From Genotyp... information processing https://petrieflom.law.harvard.edu/2024/03/11/designer-babies-the-ethical-and-regulatory-implications-of-polygenic-embryo-screening/ Designer Babies? The Ethical and Regulatory Implications of Polygenic Embryo Screening -... Oct 16, 2025 - The rise in polygenic embryo screening is ushering in a new era of human control over reproduction. designer babies ethical https://pmc.ncbi.nlm.nih.gov/articles/PMC9491373/ Clinical Implementation of Combined Monogenic and Polygenic Risk Disclosure for Coronary Artery... State-of-the-art genetic risk interpretation for a common complex disease such as coronary artery disease (CAD) requires assessment for both monogenic... https://pubmed.ncbi.nlm.nih.gov/34127801/ Performance of African-ancestry-specific polygenic hazard score varies according to local ancestry... We identified PCs within 8q24 that were strongly associated with the performance of PHS46+African. Further research to improve the clinical utility of... african ancestry https://scholars.duke.edu/publication/1501277 Scholars@Duke publication: Impact of polygenic risk for coronary artery disease and cardiovascular... https://scholars.duke.edu/publication/1506037 Scholars@Duke publication: Genome-wide analysis of genetic predisposition to common polygenic... genome wide analysis