https://pubmed.ncbi.nlm.nih.gov/26404086/
Over 50 loci associated with colorectal cancer (CRC) have been uncovered by genome-wide association studies (GWAS). Identifying additional loci has the...
genome wide associationcolorectal cancerstudy
https://pubmed.ncbi.nlm.nih.gov/25752597/
Our post-GWAS analysis of CRP GWAS SNPs confirmed the previously known overlap between CRP and lipids biology. Additionally, it suggested an important role for...
genome wide associationin silicopoststudiesanalysis
https://pubmed.ncbi.nlm.nih.gov/17632545/
Type 1 diabetes (T1D) in children results from autoimmune destruction of pancreatic beta cells, leading to insufficient production of insulin. A number of...
genome wide associationstudytype
https://pubmed.ncbi.nlm.nih.gov/30698716/
A person's lipid profile is influenced by genetic variants and alcohol consumption, but the contribution of interactions between these exposures has not been...
genome wide associationstudylipidlevelsgene
https://pubmed.ncbi.nlm.nih.gov/39812506/
Integrating multi-omics data may help researchers understand the genetic underpinnings of complex traits and diseases. However, the best ways to integrate...
kernel machinegeneralmethodsmultiomics
https://pubmed.ncbi.nlm.nih.gov/24047826/
In our genome-wide association study, we identified 3 chromosomal regions significantly associated with serum homoarginine and another region with suggestive...
genome wide associationstudygenomiclociassociated
https://www.frontiersin.org/journals/plant-science/articles/10.3389/fpls.2020.563187/full
Downy mildew, caused by the oomycete Peronospora effusa, is the most economically important disease on spinach. Fourteen new races of P. effusa have been ide...
genome wide associationfrontiersstudiesmultiplespinach
https://www.frontiersin.org/journals/plant-science/articles/10.3389/fpls.2021.648192/full
Autotetraploid alfalfa is a major hay crop planted all over the world due to its adaptation in different environments and high quality for animal feed. Howev...
genome wide associationfrontiersstudiesidentifyingmultiple
https://pubmed.ncbi.nlm.nih.gov/32779262/
Many variants with low frequencies or with low to modest effects likely remain unidentified in genome-wide association studies (GWAS) because of stringent...
frameworkpathwayknowledgedrivenprioritization
https://pubmed.ncbi.nlm.nih.gov/21647738/
Recent genome-wide association studies have related several genetic loci, including C-reactive protein (CRP), hepatocyte nuclear factor 1 homeobox (HNF1A), and...
genome wide associationreactiveproteinlevels