prc2 - Robuta Search

https://pubmed.ncbi.nlm.nih.gov/30472157/ Integrative Proteomic Profiling Reveals PRC2-Dependent Epigenetic Crosstalk Maintains Ground-State... The pluripotent ground state is defined as a basal state free of epigenetic restrictions, which influence lineage specification. While naive embryonic stem... integrative proteomic profiling reveals https://www.frontiersin.org/journals/cell-and-developmental-biology/articles/10.3389/fcell.2022.1003349/full Frontiers | PRC2-dependent regulation of ganglioside expression during dedifferentiation... Phenotypic switching between contractile (differentiated state) and proliferative (dedifferentiated state) vascular smooth muscle cells (VSMCs) is a hallmark... frontiers dependent regulation expression https://collaborate.princeton.edu/en/publications/targeted-histone-peptides-insights-into-the-spatial-regulation-of/ Targeted histone peptides: Insights into the spatial regulation of the methyltransferase PRC2 by... https://pubmed.ncbi.nlm.nih.gov/27526204/ Polycomb repressive complex 2 (PRC2) silences genes responsible for neurodegeneration Normal brain function depends on the interaction between highly specialized neurons that operate within anatomically and functionally distinct brain regions.... repressive complex silences genes responsible https://necat.chem.cornell.edu/discovery-peptidomimetic-ligands-eed-allosteric-inhibitors-prc2 Discovery of Peptidomimetic Ligands of EED as Allosteric Inhibitors of PRC2. | NECAT discovery ligands eed allosteric inhibitors https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.0060093 Polycomb Repressive Complex 2 (PRC2) Restricts Hematopoietic Stem Cell Activity | PLOS Biology Epigenetic modifications are central to the maintenance of cellular identity and are dynamically regulated during differentiation. We addressed the role of... https://dbbs.wustl.edu/events/event/speaker-kuangying-yang-dissecting-tumor-evolution-and-immune-composition-in-prc2-loss-h3k27me3-loss-versus-retained-mpnst/ Speaker: Kuangying Yang - "Dissecting Tumor Evolution and Immune Composition in PRC2-Loss... PhD Program in Human and Statistical Genetics Laboratory of Dr. Angela Hirbe Department of Medicine https://collaborate.princeton.edu/en/publications/nucleation-and-propagation-of-heterochromatin-by-the-histone-meth/fingerprints/?sortBy=alphabetically Nucleation and Propagation of Heterochromatin by the Histone Methyltransferase PRC2: Geometric... by the histone methyltransferase nucleation propagation https://pubmed.ncbi.nlm.nih.gov/24244202/ A genetic approach to the recruitment of PRC2 at the HoxD locus Polycomb group (PcG) proteins are essential for the repression of key factors during early development. In Drosophila, the polycomb repressive complexes (PRC)... to the genetic approach https://vivo.colorado.edu/display/pubid_258132 C9orf72 and triplet repeat disorder RNAs: G-quadruplex formation, binding to PRC2 and implications... https://umu.diva-portal.org/smash/record.jsf?pid=diva2:1694329&language=sv PRC2-mediated repression is essential to maintain identity and function of differentiated... https://pittlab.weill.cornell.edu/publications/distinct-specificity-and-functions-prc2-subcomplexes-human-stem-cells-and-cardiac Distinct specificity and functions of PRC2 subcomplexes in human stem cells and cardiac... human stem cells https://pubmed.ncbi.nlm.nih.gov/34994686/?dopt=Abstract PRC1 sustains the integrity of neural fate in the absence of PRC2 function Polycomb repressive complexes (PRCs) 1 and 2 maintain stable cellular memories of early fate decisions by establishing heritable patterns of gene repression.... sustains integrity https://cordis.europa.eu/project/id/101025853 The role of Polycomb Repressive Complex 2 (PRC2) in plant acclimation to ambient light | RPAAL |... Polycomb Repressive Complex 2 (PRC2) is an evolutionarily conserved histone methyltransferase complex that catalyses trimethylation of lysine 27 of histone H3... https://pubchem.ncbi.nlm.nih.gov/bioassay/1795834 AID 1795834 - Wild-Type and Mutant PRC2 Enzyme Assays from US Patent US10098888: "Substituted... BioAssay record AID 1795834 submitted by BindingDB: Wild-Type and Mutant PRC2 Enzyme Assays from US Patent US10098888: https://collaborate.princeton.edu/en/publications/prc2-engages-a-bivalent-h3k27m-h3k27me3-dinucleosome-inhibitor/ PRC2 engages a bivalent H3K27M-H3K27me3 dinucleosome inhibitor - Princeton University engages bivalent inhibitor princeton university