Robuta

My goal is to test whether structure-based approaches can guide the design of PROTACs. As a first step, I am evaluating whether protein-protein docking tools...

Innovative preclinical model systems are transforming PROTAC development by providing deeper insight into pharmacology.

Streamlight Inc., a leading provider of high-performance lighting and weapon light/laser sighting devices, introduced the ProTac HL 3, a high lumen (HL) light...

Apr 28, 2025 - Streamlight ProTac Rail Mount HL-X: A Thoroughly Bright Review In a world that can get unexpectedly dark, whether you’re negotiating the treacherous

Crystal structure of DDB1-CRBN-BRD4(BD1) complex bound to dBET57 PROTAC

Crystal structure of PROTAC CFT-1297 in complex with CRBN-midi and BRD4(BD2)

Nanocrystal drugs are characterized by particle sizes in the nanometer range, typically below 1 ?...

BackgroundCelastrol is an effective component of the plant Tripterygium wilfordii Hook. f., which has a high inhibitory effect on triple-negative breast canc...

Targeted protein degradation is one of the fastest developing fields in medicinal chemistry and chemical biology. Despite significant development in assay...

A rapamycin-induced proximity assay enables rapid identification of optimal E3 ligases for target protein degradation in living cells, streamlining early-stage...

There are currently 71 PROTACs in development for oncology by non-academic developers, mostly in the preclinical and discovery phases.