Robuta

https://www.research.va.gov/about/funded_research/proj-details-FY2019.cfm?pid=490977 I01BX000596-05A2 - Targeting Renal Purinergic Signaling for the Treatment of Lithium-induced NDI https://scholarshare.temple.edu/entities/publication/354e5174-20f3-4f73-b12f-0f922d2b5786 Sex-related differences in the response of anti-platelet drug therapies targeting purinergic... Sepsis, a complex clinical syndrome resulting from a serious infection, is a major healthcare problem associated with high mortality. Sex-related differences... https://pubmed.ncbi.nlm.nih.gov/8230554/ Evidence for purinergic neurotransmission in human urinary bladder affected by interstitial cystitis Detrusor specimens were obtained from 5 patients affected by interstitial cystitis (IC) and 5 patients with bladder carcinoma (controls). Muscle strips were... in human https://www.research.ed.ac.uk/en/publications/purinergic-signaling-in-kidney-disease/projects/?status=FINISHED Purinergic Signaling in Kidney Disease - Projects - University of Edinburgh Research Explorer university of edinburghkidney diseasepurinergicsignaling https://pubmed.ncbi.nlm.nih.gov/30016729/ Catestatin is involved in neuropathic pain mediated by purinergic receptor P2X4 in the spinal... https://experts.umn.edu/en/publications/purinergic-signalling-in-the-kidney-in-health-and-disease/fingerprints/?sortBy=alphabetically Purinergic signalling in the kidney in health and disease - Fingerprint - Experts@Minnesota health and diseasein thepurinergicsignallingkidney https://pubmed.ncbi.nlm.nih.gov/17941929/ Purinergic receptor-mediated effects of ATP in high-grade bladder cancer ATP effectively reduces the growth of high-grade bladder cancer cells in vitro and in vivo. This highlights the potential use of ATP in the treatment of... high gradepurinergicreceptormediatedeffects https://pubmed.ncbi.nlm.nih.gov/22753942/ Extracellular ATP exerts opposite effects on activated and regulatory CD4+ T cells via purinergic... It has been reported that ATP inhibits or stimulates lymphoid cell proliferation depending on the cellular subset analyzed. In this study, we show that ATP... https://pubmed.ncbi.nlm.nih.gov/21094205/ ADP ribose is an endogenous ligand for the purinergic P2Y1 receptor The mechanism by which extracellular ADP ribose (ADPr) increases intracellular free Ca(2+) concentration ([Ca(2+)](i)) remains unknown. We measured [Ca(2+)](i)... for theadpriboseendogenous https://www.research.va.gov/about/funded_research/proj-details-FY2022.cfm?pid=567715 IK2BX003509-01A2 - Purinergic signaling and arteriogenesis purinergicsignaling https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2017.00661/full Frontiers | Purinergic Signalling: Therapeutic Developments Purinergic signalling, i.e. the role of nucleotides as extracellular signalling molecules, was proposed in 1972. However, this concept was not well accepted ... frontierspurinergicsignallingtherapeuticdevelopments https://iris.cnr.it/handle/20.500.14243/167806 Membrane compartments and purinergic signalling membranecompartmentspurinergicsignalling https://www.semanticscholar.org/topic/purinergic-nucleotide-receptor-activity/165894 purinergic nucleotide receptor activity | Semantic Scholar Combining with a purine nucleotide and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. [GOC:mah,... purinergicnucleotidereceptoractivitysemantic https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2022.1012534/full Frontiers | Evaluation of nanobody-based biologics targeting purinergic checkpoints in tumor models... Adenosine triphosphate (ATP) represents a danger signal that accumulates in injured tissues, in inflammatory sites, and in the tumor microenvironment. ATP pr... https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2023.1227873/full Frontiers | Differential expression patterns of purinergic ectoenzymes and the antioxidative role... We have acquired significant knowledge regarding the pathogenesis of severe acute respiratory syndrome caused by coronavirus 2 (SARS-CoV-2). However, the und... differential expressionand thefrontierspatterns https://pubmed.ncbi.nlm.nih.gov/29739879/ Chemical synapses without synaptic vesicles: Purinergic neurotransmission through a CALHM1... Conventional chemical synapses in the nervous system involve a presynaptic accumulation of neurotransmitter-containing vesicles, which fuse with the plasma... chemicalsynapseswithoutsynapticvesicles https://pubs.rsc.org/en/content/articlelanding/2016/fo/c5fo00871a Naringenin ameliorates renal and platelet purinergic signalling alterations in high-cholesterol fed... Naringenin (NGEN) is a natural flavonoid aglycone of naringin that has been reported to have a wide range of pharmacological properties, such as antioxidant... https://www.jstage.jst.go.jp/article/jphs/116/4/116_11069FP/_article Selective Upregulation of Per1 mRNA Expression by ATP Through Activation of P2X7 Purinergic... Access full-text academic articles: J-STAGE is an online platform for Japanese academic journals.