Robuta

https://pubmed.ncbi.nlm.nih.gov/9774334/
Angiogenesis, the sprouting of new blood vessels from pre-existing ones, is an essential physiological process in development, yet also plays a major role in...
crystal structureangiogenesis inhibitorboundfgf
https://pubmed.ncbi.nlm.nih.gov/37984347/
EGFR-TKIs and ICIs are effective for treating recurrent NSCLC after surgery. Although adjuvant chemotherapy for completely resected pathological stage II to...
epidermal growth factorreceptor tyrosine kinaserelativeinhibitors
https://pubmed.ncbi.nlm.nih.gov/29045907/
Inhibitors of the receptor tyrosine kinase c-MET are currently used in the clinic to target oncogenic signaling in tumor cells. We found that concomitant c-MET...
receptor tyrosine kinaseon thereactiveneutrophilresponses
https://www.mcgill.ca/channels/event/mechanisms-down-regulation-met-receptor-tyrosine-kinase-29470
Senior Seminar: Jasmine Abella, Morag Park's Lab
receptor tyrosine kinasethe metmechanismsregulation
https://pubmed.ncbi.nlm.nih.gov/39960754/
Mutations in the kinase and juxtamembrane domains of the MET Receptor Tyrosine Kinase are responsible for oncogenesis in various cancers and can drive...
the metmappingkinasedomainresistance
https://elifesciences.org/articles/82863/figures
pYtags are novel biosensors that can be used to measure the activity of a receptor tyrosine kinase of interest in live cells with high spatiotemporal...
figuresdataenablespatiotemporalmeasurements