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Robuta

https://pubmed.ncbi.nlm.nih.gov/21349544/
Altered sirtuin deacetylase gene expression in patients with a mood disorder
Sirtuins are a family of NAD+-dependent enzymes that regulate cellular functions through deacetylation of various proteins. Although recent reports have...
gene expressiona moodalteredsirtuindeacetylase
https://www.ncbi.nlm.nih.gov/Structure/pdb/2H2D
2H2D: The Structural Basis for Sirtuin Substrate Affinity
Cellular tumor antigen p53 peptideNAD-dependent deacetylaseZINC ION
substrate affinitystructuralbasissirtuin