sod1 - Robuta Search

https://www.rcsb.org/structure/2RSQ RCSB PDB - 2RSQ: Copper(I) loaded form of the first domain of the human copper chaperone for SOD1,... Copper(I) loaded form of the first domain of the human copper chaperone for SOD1, CCS https://elifesciences.org/reviewed-preprints/91611 SOD1 is a synthetic lethal target in PPM1D-mutant leukemia cells is a sod1 synthetic lethal https://www.jci.org/articles/view/34060/citations JCI - Citations to SOD1 mutations disrupt redox-sensitive Rac regulation of NADPH oxidase in a... https://www.uow.edu.au/media/2025/drug-breakthrough-sparks-hope-for-families-affected-by-mnd-gene-sod1.php 2025 | Drug breakthrough sparks hope for families affected by MND gene SOD1 - University of... https://www.mdpi.com/1422-0067/24/1/659 Unbalance between Pyridine Nucleotide Cofactors in The SOD1 Deficient Yeast Saccharomyces... Alcohol and aldehyde dehydrogenases are especially relevant enzymes involved in metabolic and detoxification reactions that occur in living cells. The... in the unbalance pyridine nucleotide cofactors https://pmc.ncbi.nlm.nih.gov/articles/PMC4004233/ Non-native Soluble Oligomers of Cu/Zn Superoxide Dismutase (SOD1) Contain a Conformational Epitope... Soluble misfolded Cu/Zn superoxide dismutase (SOD1) is implicated in motor neuron death in amyotrophic lateral sclerosis (ALS); however, the relative... cu zn superoxide dismutase https://www.jci.org/articles/view/34060 JCI - SOD1 mutations disrupt redox-sensitive Rac regulation of NADPH oxidase in a familial ALS model https://www.jax.org/strain/002299 002299 - G93A SOD1 Strain Details g93a sod1 strain details https://elifesciences.org/reviewed-preprints/89298/figures EphrinB2 knockdown in cervical spinal cord preserves diaphragm innervation in a mutant SOD1 mouse... cervical spinal cord https://elifesciences.org/reviewed-preprints/89298v1/reviews EphrinB2 knockdown in spinal cord astrocytes preserves diaphragm innervation in a mutant SOD1 mouse... https://www.globenewswire.com/news-release/2025/02/11/3024034/36461/en/Voyager-Provides-Update-on-SOD1-ALS-Gene-Therapy-Program.html Voyager Provides Update on SOD1 ALS Gene Therapy Program - Company to assess alternate payloads; no changes planned to novel capsid component - - Resulting shift of timeline and costs extends cash runway into... gene therapy voyager provides update sod1 https://www.frontiersin.org/journals/neuroanatomy/articles/10.3389/fnana.2017.00022/full Frontiers | Overexpression of Human SOD1 Leads to Discrete Defects in the Cerebellar Architecture... The human superoxide dismutase 1 (SOD1) gene is responsible for neutralizing supercharged oxygen radicals within the cell. Mutation in SOD1 gene causes amyo... https://www.semanticscholar.org/topic/SOD1-wt-Allele/663524 SOD1 wt Allele | Semantic Scholar Human SOD1 wild-type allele is located within 21q22 and is approximately 9 kb in length. This allele, which encodes superoxide dismutase [Cu-Zn] protein, is... sod1 wt allele semantic scholar https://www.rcsb.org/structure/4MCN RCSB PDB - 4MCN: Human SOD1 C57S Mutant, Metal-free Human SOD1 C57S Mutant, Metal-free rcsb pdb human sod1 mutant metal https://www.mayo.edu/research/clinical-trials/cls-20577059 Intrathecally Administered Gene Therapy APB-102 In Rapidly Progressive ALS Patients With SOD1... Learn more about services at Mayo Clinic. https://pmc.ncbi.nlm.nih.gov/articles/PMC5093072/ A Phosphomimetic Mutation Stabilizes SOD1 and Rescues Cell Viability in the Context of an... The majority of amyotrophic lateral sclerosis (ALS)-related mutations in the enzyme Cu, Zn superoxide dismutase (SOD1), as well as a post-translational... https://pmc.ncbi.nlm.nih.gov/articles/PMC22528/ Overexpression of human copper,zinc-superoxide dismutase (SOD1) prevents postischemic injury - PMC Superoxide and superoxide-derived oxidants have been hypothesized to be important mediators of postischemic injury. Whereas copper,zinc-superoxide dismutase,... superoxide dismutase https://elifesciences.org/reviewed-preprints/89298v3 EphrinB2 knockdown in cervical spinal cord preserves diaphragm innervation in a mutant SOD1 mouse... cervical spinal cord https://www.ncbi.nlm.nih.gov/Structure/pdb/3H2Q 3H2Q: Human SOD1 H80R variant, P21 crystal form Superoxide dismutase [Cu-Zn]SULFATE IONZINC ION human sod1 variant p21 crystal