https://www.jci.org/articles/view/124159
JCI - DEGS1-associated aberrant sphingolipid metabolism impairs nervous system function in humans
sphingolipid metabolism
https://www.universiteitleiden.nl/en/research/research-output/science/the-synthesis-of-chemical-tools-for-studying-sphingolipid-metabolism
The synthesis of chemical tools for studying sphingolipid metabolism - Leiden University
Sphingolipids are important membrane compounds with a variety of functions. In mammalian cells, different enzymes are involved in the metabolism of...
tools for studyingsphingolipid metabolismsynthesischemical
https://www.mdpi.com/2073-4409/11/11/1840
Lysosomal Proteomics Links Disturbances in Lipid Homeostasis and Sphingolipid Metabolism to CLN5...
CLN5 disease (MIM: 256731) represents a rare late-infantile form of neuronal ceroid lipofuscinosis (NCL), caused by mutations in the CLN5 gene that encodes the...
https://www.jci.org/articles/view/194427/pdf
JCI - Redirection of sphingolipid metabolism drives cytoskeletal defects in SPLIS and reveals ROCK...
https://www.frontiersin.org/journals/oncology/articles/10.3389/fonc.2022.941643/full
Frontiers | The key role of sphingolipid metabolism in cancer: New therapeutic targets, diagnostic...
Biologically active sphingolipids are closely related to the growth, differentiation, aging, and apoptosis of cancer cells. Some sphingolipids, such as ceram...
https://elifesciences.org/reviewed-preprints/89938v3
Membrane contact sites regulate vacuolar fission via sphingolipid metabolism
membrane contact sitesregulatevacuolarfissionvia
https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2023.1115272/full
Frontiers | By integrating single-cell RNA-seq and bulk RNA-seq in sphingolipid metabolism, CACYBP...
AbstractBackground: Lung adenocarcinoma (LUAD) is a heterogeneous disease with a dismal prognosis for advanced tumors. Immune-associated cells in the microen...