https://pubchem.ncbi.nlm.nih.gov/protein/I3L807
Sphingosine kinase 2 (pig) | Protein Target - PubChem
Protein target information for Sphingosine kinase 2 (pig). Find diseases associated with this biological target and compounds tested against it in bioassay...
sphingosine kinasepigproteintargetpubchem
https://pure.psu.edu/en/publications/targeting-sphingosine-kinase-induces-apoptosis-and-tumor-regressi/
Targeting sphingosine kinase induces apoptosis and tumor regression for KSHV-associated primary...
sphingosine kinase
https://vtechworks.lib.vt.edu/items/67f3057d-f529-4a5d-b605-b1bb28fcf037/full
Design and Synthesis of Orally Bioavailable Sphingosine Kinase 2 Selective Inhibitors
In humans, mammals, and perhaps all vertebrates, sphingolipids exist as a family of cellular signaling molecules and have been shown to be involved in a wide...
sphingosine kinasedesignsynthesisorally
https://www.frontiersin.org/journals/endocrinology/articles/10.3389/fendo.2020.627076/full
Frontiers | Role of Sphingosine Kinase in Type 2 Diabetes Mellitus
Sphingolipids are a class of essential lipids, functioning as both cell membrane constituents and signaling messengers. In the sphingolipid metabolic network...
sphingosine kinasefrontiersroletypediabetes
https://pubmed.ncbi.nlm.nih.gov/25253697/
Adipocyte lipolysis-stimulated interleukin-6 production requires sphingosine kinase 1 activity
Adipocyte lipolysis can increase the production of inflammatory cytokines such as interleukin-6 (IL-6) that promote insulin resistance. However, the mechanisms...
sphingosine kinaseadipocytelipolysisstimulatedinterleukin
https://experts.arizona.edu/en/publications/role-of-sphingosine-kinase-1-in-paracrinetranscellular-angiogenes/
Role of sphingosine kinase-1 in paracrine/transcellular angiogenesis and lymphangiogenesis in vitro...
sphingosine kinase
https://pure.psu.edu/en/publications/development-of-ski-349-a-dual-targeted-inhibitor-of-sphingosine-k/
Development of SKI-349, a dual-targeted inhibitor of sphingosine kinase and microtubule...
https://dukespace.lib.duke.edu/items/b0f05f70-b50b-47e3-bcdb-47d6e312f1a1/full
Inhibition of Sphingosine Kinase 2 Results in PARK2-Mediated Mitophagy and Induces Apoptosis in...
Mitophagy plays an important role in maintaining mitochondrial homeostasis by clearing damaged mitochondria. Sphingosine kinase 2 (SK2), a type of sphingosine...
https://pure.psu.edu/en/publications/attenuation-of-arthritis-in-rodents-by-a-novel-orally-available-i/
Attenuation of arthritis in rodents by a novel orally-available inhibitor of sphingosine kinase -...
https://pure.psu.edu/en/publications/sphingosine-kinase-1-protein-and-mrna-are-overexpressed-in-non-ho/
Sphingosine kinase 1 protein and mRNA are overexpressed in non-Hodgkin lymphomas and are attractive...
https://pubmed.ncbi.nlm.nih.gov/27505892/
Visualizing red blood cell sickling and the effects of inhibition of sphingosine kinase 1 using...
Sickle cell disease is a destructive genetic disorder characterized by the formation of fibrils of deoxygenated hemoglobin, leading to the red blood cell (RBC)...
https://scholarspace.manoa.hawaii.edu/items/9f50f6b6-5d9c-405c-85e0-1a9860da0804
Regulation of Sphingosine Kinase 1 and Adipose Inflammation by Momordica charantia (Bitter Melon)...
In Hawaii, Native Hawaiian and Pacific Islanders have the highest rates of obesity as compared to Caucasians. Lifestyle changes such as diet and exercise form...
https://academiccommons.columbia.edu/doi/10.7916/D8F47M4B
Isoflurane Protects Against Human Endothelial Cell Apoptosis by Inducing Sphingosine Kinase-1 via...
Endothelial dysfunction is a major clinical problem affecting virtually every patient requiring critical care. Volatile anesthetics are frequently used during...