https://www.frontiersin.org/journals/chemical-biology/articles/10.3389/fchbi.2024.1517163/full
Frontiers | Exploring the NANOG-TET2 interaction interface. Effects of a selected mutation and...
In this study, we focused on the computational analysis of a selected single-point mutation identified by a NGS screening panel in the TET2 enzyme classified...
https://pubmed.ncbi.nlm.nih.gov/22902501/
Early-stage epigenetic modification during somatic cell reprogramming by Parp1 and Tet2
Somatic cells can be reprogrammed into induced pluripotent stem cells (iPSCs) by using the pluripotency factors Oct4, Sox2, Klf4 and c-Myc (together referred...
early stage
https://pubmed.ncbi.nlm.nih.gov/38573824/
Neutrophil-mediated innate immune resistance to bacterial pneumonia is dependent on Tet2 function
Individuals with clonal hematopoiesis of indeterminate potential (CHIP) are at increased risk of aging related health conditions and all-cause mortality, but...
https://scholarworks.indianapolis.iu.edu/items/f0e29805-8281-4998-9aad-b9b1ec390fd9/request-a-copy?bitstream=29cfce71-9a6a-4678-852b-71de4157ceaf
The Role of Inflammatory Signaling Pathways in TET2-Deficient Hematological Malignancies
Loss of the TET2 gene, which is commonly mutated in the pre-leukemic condition clonal hematopoiesis of indeterminate potential (CHIP) and hematological...
the rolesignaling pathwaysinflammatory
https://pubmed.ncbi.nlm.nih.gov/32193150/
TET2 haploinsufficiency alters reprogramming into induced pluripotent stem cells
The discovery of the Ten-Eleven Translocation (TET) protein family was initiated by the identification of the MLL partner TET1, and of mutations in the TET2...
haploinsufficiencyaltersreprogramminginducedpluripotent
https://eprints.ncl.ac.uk/267757
Germline TET2 loss-of-function causes childhood immunodeficiency and lymphoma - ePrints - Newcastle...
loss of function
https://vivo.colorado.edu/display/pubid_261882
Transcription Factors Drive Tet2-Mediated Enhancer Demethylation to Reprogram Cell Fate | CU...
transcription factors
https://pubmed.ncbi.nlm.nih.gov/36639817/?dopt=Abstract
Vitamin C boosts DNA demethylation in TET2 germline mutation carriers
This trial was registered at EudraCT with reference number of 2018-000155-41 (01.04.2019).
vitamin cboostsdnagermlinemutation
https://pubmed.ncbi.nlm.nih.gov/32596441/
TET2 deficiency reprograms the germinal center B cell epigenome and silences genes linked to...
The TET2 DNA hydroxymethyltransferase is frequently disrupted by somatic mutations in diffuse large B cell lymphomas (DLBCLs), a tumor that originates from...
https://research.ugent.be/web/result/project/47013bd2-225c-11ea-9b15-d7676230cb7f/details/en
Research Explorer - (3G009320) The role of TET2 in (pre)-leukemic T-cell acute lymphoblastic...
Research Explorer - Basic information about research project The role of TET2 in (pre)-leukemic T-cell acute lymphoblastic leukemia (3G009320). - T-cell acute...
https://open.library.emory.edu/concern/publications/f4244440-45c0-4cbf-944a-a52046d012c4
Combined Loss of Tet1 and Tet2 Promotes B Cell, but Not Myeloid Malignancies, in Mice | OpenEmory
Combined Loss of Tet1 and Tet2 Promotes B Cell, but Not Myeloid Malignancies, in Mice
https://pubmed.ncbi.nlm.nih.gov/28416650/
Epigenetic regulator CXXC5 recruits DNA demethylase Tet2 to regulate TLR7/9-elicited IFN response...
TLR7/9 signals are capable of mounting massive interferon (IFN) response in plasmacytoid dendritic cells (pDCs) immediately after viral infection, yet the...