pluripotent - Robuta Search

https://pubmed.ncbi.nlm.nih.gov/32571490/

Induced pluripotent stem cells provide mega insights into kidney disease

Rare mutations in the LRP2 gene encoding for the endocytic receptor megalin cause developmental abnormalities and kidney disease. However, the mechanisms...

induced pluripotent stem kidney disease cells provide mega

https://www.adamslab.nl/research-lines/population-based-induction-of-pluripotent-stem-cells/

Population-based induction of pluripotent stem cells - Adams Lab

Induced pluripotent stem cells (iPSCs), derived from easily accessible tissues like skin or blood, have been lauded as critical tool to model how genetic...

pluripotent stem cells population based induction adams

https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2022.991072/full

Frontiers | Differentiation and on axon-guidance chip culture of human pluripotent stem...

Airway cholinergic nerves play a key role in airway physiology and disease. In asthma and other diseases of the respiratory tract, airway cholinergic neurons...

axon guidance frontiers differentiation chip culture

https://elifesciences.org/reviewed-preprints/89724

Complete suspension culture of human induced pluripotent stem cells supplemented with suppressors...

induced pluripotent stem suspension culture complete human cells

https://www.thermofisher.com/us/en/home/references/protocols/cell-culture/transfection-protocol/transfection-pscs-lipofectamine-stem-transfection-reagent-stemflex-medium.html

Transfection of Pluripotent Stem Cells with Lipofectamine Stem Transfection Reagent in StemFlex...

pluripotent stem cells transfection lipofectamine reagent

https://pubmed.ncbi.nlm.nih.gov/38579720/

Basal delamination during mouse gastrulation primes pluripotent cells for differentiation

The blueprint of the mammalian body plan is laid out during gastrulation, when a trilaminar embryo is formed. This process entails a burst of proliferation,...

basal delamination mouse gastrulation primes

https://pubmed.ncbi.nlm.nih.gov/33116297/

YAP-TEAD1 control of cytoskeleton dynamics and intracellular tension guides human pluripotent stem...

The tight regulation of cytoskeleton dynamics is required for a number of cellular processes, including migration, division and differentiation. YAP-TEAD...

yap control cytoskeleton dynamics intracellular

https://pubmed.ncbi.nlm.nih.gov/33636116/

Maturation of Pluripotent Stem Cell-Derived Cardiomyocytes Enables Modeling of Human Hypertrophic...

Human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) are a powerful platform for biomedical research. However, they are immature, which is a...

pluripotent stem cell maturation derived cardiomyocytes modeling

https://www.sciencedaily.com/releases/2022/04/220407101103.htm

Advancing maturation of human pluripotent stem cell-derived heart cells | ScienceDaily

New study outlines scalable protocol to enhance development and understanding of human pluripotent stem cells in cardiac muscles.

pluripotent stem cell heart cells maturation human derived

https://plathlab.org/publication/from-skin-biopsy-to-neurons-through-a-pluripotent-intermediate-under-good-manufacturing-practice-protocols/

From skin biopsy to neurons through a pluripotent intermediate under Good Manufacturing Practice...

skin biopsy neurons pluripotent intermediate

https://www.fudahospital.com/zlyj/zjlw/3111.html

2017-E15_Generation of non-integrated induced pluripotent stem cells from a 59-year-old female with...

induced pluripotent stem generation non integrated cells

https://elifesciences.org/articles/90695/peer-reviews

Peer review in Human-induced pluripotent stem cell-derived microglia integrate into mouse retina...

Transplanted human iPSC-derived microglial cells with immune responses and phagocytic abilities integrate and occupy native microglial cell space and...

induced pluripotent stem peer review human cell derived

https://pubmed.ncbi.nlm.nih.gov/41293951/

Epigenomic alterations and neural development anomalies in induced pluripotent stem cells from...

Reprogramming of adult somatic cells into induced pluripotent stem cells (iPSCs) resets the aging clock. However, primed iPSCs can retain cell-of-origin...

induced pluripotent stem neural development epigenomic alterations anomalies

https://pubmed.ncbi.nlm.nih.gov/37762684/

Myogenetic Oligodeoxynucleotide Induces Myocardial Differentiation of Murine Pluripotent Stem Cells

An 18-base myogenetic oligodeoxynucleotide (myoDN), iSN04, acts as an anti-nucleolin aptamer and induces myogenic differentiation of skeletal muscle myoblasts....

pluripotent stem cells oligodeoxynucleotide induces myocardial differentiation

https://www.fda.gov/vaccines-blood-biologics/science-research-biologics/high-replication-rate-induced-pluripotent-stems-cells-appears-contribute-breaks-dna

High replication rate of induced pluripotent stems cells appears to contribute to breaks in DNA |...

Summary of research article for posting on the Research Summaries section of CBER Innovation web site.

high replication rate induced pluripotent

https://www.wikidata.org/wiki/Q37211408

Reprogramming of murine fibroblasts to induced pluripotent stem cells with chemical complementation...

scientific article published on 15 May 2009

induced pluripotent stem reprogramming murine fibroblasts cells

https://pubmed.ncbi.nlm.nih.gov/41556260/?utm_source=SimplePie&utm_medium=rss&utm_campaign=pubmed-2&utm_content=1VUFS2KU_hFnBUajs3hlb00hHBOGRVXZp7ZhDB0wD6N0LBD9Nk&fc=20250423082013&ff=20260120124739&v=2.18.0.post22+67771e2

Introducing Cellular Senescence in Human Induced Pluripotent Stem Cells and Differentiated Neural...

Reprogramming somatic cells into induced pluripotent stem cells (iPSCs) resets the epigenetic landscapes that mark the aging clock, and consequently cells...

induced pluripotent stem cellular senescence introducing human cells

https://www.neuronatherapeutics.com/technology/

Regenerative Pluripotent Stem Cell Technology | Neurona Therapeutics

Neurona is developing off-the-shelf, allogeneic neuronal, glial, and gene-edited neural cell therapies for single-dose targeted repair of the nervous system.

pluripotent stem cell regenerative technology neurona therapeutics

https://pubmed.ncbi.nlm.nih.gov/28527889/

Enhanced cardiomyogenic induction of mouse pluripotent cells by cyclic mechanical stretch

The cardiac milieu is mechanically active with spontaneous contraction beginning from early development and persistent through maturation and homeostasis,...

enhanced induction mouse pluripotent cells

https://pubmed.ncbi.nlm.nih.gov/23063362/

Induced pluripotent stem cell models of progranulin-deficient frontotemporal dementia uncover...

The pathogenic mechanisms of frontotemporal dementia (FTD) remain poorly understood. Here we generated multiple induced pluripotent stem cell lines from a...

induced pluripotent stem frontotemporal dementia cell models progranulin

https://pubmed.ncbi.nlm.nih.gov/17560561/

Global gene expression profiling reveals similarities and differences among mouse pluripotent stem...

Pluripotent stem cell lines with similar phenotypes can be derived from both blastocysts (embryonic stem cells, ESC) and primordial germ cells (embryonic germ...

gene expression profiling global reveals similarities differences

https://pubmed.ncbi.nlm.nih.gov/41512874/

Human pluripotent stem cell-derived innate and adaptive immune cells for cancer immunotherapy

Allogeneic cell-based therapies hold great promise for cancer immunotherapy but face challenges like scalability, immune rejection, graft-versus-host disease,...

pluripotent stem cell immune cells human derived innate

https://pubmed.ncbi.nlm.nih.gov/21151107/

Directed differentiation of human pluripotent stem cells into intestinal tissue in vitro

Studies in embryonic development have guided successful efforts to direct the differentiation of human embryonic and induced pluripotent stem cells (PSCs) into...

pluripotent stem cells directed differentiation human intestinal tissue

https://pubmed.ncbi.nlm.nih.gov/34883115/

Modeling Developmental Brain Diseases Using Human Pluripotent Stem Cells-Derived Brain Organoids -...

Developmental brain diseases encompass a group of conditions resulting from genetic or environmental perturbations during early development. Despite the...

pluripotent stem cells brain diseases modeling developmental using

https://pubmed.ncbi.nlm.nih.gov/30401455/

SUMO Safeguards Somatic and Pluripotent Cell Identities by Enforcing Distinct Chromatin States

Understanding general principles that safeguard cellular identity should reveal critical insights into common mechanisms underlying specification of varied...

sumo safeguards somatic pluripotent cell

https://elifesciences.org/articles/07103

A panel of induced pluripotent stem cells from chimpanzees: a resource for comparative functional...

A panel of chimpanzee induced pluripotent stem cells (iPSCs) will help realise the potential of iPSCs in primate studies, and in combination with genomic...

induced pluripotent stem panel cells chimpanzees

https://pubmed.ncbi.nlm.nih.gov/21936964/

Induced pluripotent stem cells in the study of neurological diseases

Five years after their initial derivation from mouse somatic cells, induced pluripotent stem (iPS) cells are an important tool for the study of neurological...

induced pluripotent stem the study neurological diseases cells