Robuta

https://pmc.ncbi.nlm.nih.gov/articles/PMC64844/ The inhibitory effects of camptothecin, a topoisomerase I inhibitor, on collagen synthesis in... The main manifestation of systemic sclerosis (SSc) is the overproduction of extracellular matrix, predominantly type I collagen. This study was undertaken to... topoisomerase i inhibitorinhibitoryeffectscamptothecincollagen