https://www.nokia.com/bell-labs/publications-and-media/publications/mutation-selection-networks-of-cancer-initiation-tumor-suppressor-genes-and-chromosomal-instability/
In this paper, we derive analytic solutions of stochastic mutation-selection networks that describe early events of cancer formation. A main assumption is that...
tumor suppressor genescancer initiationmutationselectionnetworks
https://www.preprints.org/manuscript/201903.0187
Silencing of tumor suppressor genes (TSGs) by DNA promoter hypermethylation is an earlyevent in carcinogenesis; Hence TSGs may serve as early tumor biomarkers....
tumor suppressor genespromoterhypermethylation