https://pentabase.com/epidirect-methylation-qpcr-assays/
Dec 2, 2025 - EpiDirect® Methylation qPCR Assays - Measure DNA methylation status of purified DNA without the need for prior bisulfite treatment.
methylationqpcrassays
https://link.springer.com/article/10.1007/s00726-025-03495-w?error=cookies_not_supported&code=e7a6fc94-d314-4890-88ab-b0e124607192
Dec 22, 2025 - Methionine is an essential amino acid for the human body. Understanding how tumor cells adjust their signaling networks to evade apoptosis and sustain prol
methylationdependentdegradationsignalingpromote
https://pubmed.ncbi.nlm.nih.gov/32293262/?dopt=Abstract
A companion manuscript shows that these cell states dramatically affect protein abundances, cell and mitochondrial morphology, and glycolytic metabolism. We...
effectsmetabolismgenomicmutationcpg
https://pubmed.ncbi.nlm.nih.gov/31158293/
The models developed and validated in this study provide important prognostic information not captured by previously established clinical and molecular factors...
dna methylationprofilingpredictrecurrencerisk
https://pubmed.ncbi.nlm.nih.gov/37533074/
This meta-analysis confirmed the great potential of DNA methylation-based biomarkers as triage tool for hrHPV-positive women in cervical cancer screening....
dna methylationtriagemarkercolposcopyreferral
https://pubmed.ncbi.nlm.nih.gov/29438328/
Viruses have evolved various mechanisms to evade host immunity and ensure efficient viral replication and persistence. Several DNA tumor viruses modulate host...
dna tumor virusregulationhostmethylation
https://link.springer.com/article/10.1186/s12987-023-00414-7?error=cookies_not_supported&code=c6ee7d33-dd5d-4932-9ad2-14590485ad74
Feb 28, 2023 - Incomplete recovery of blood–brain barrier (BBB) function contributes to stroke outcomes. How the BBB recovers after stroke remains largely unknown.
and strokedna methylationepigeneticsroleeffect
https://www.frontiersin.org/journals/medicine/articles/10.3389/fmed.2020.579383/full
The mRNA-destabilizing protein Tristetraprolin (TTP), encoded by the ZFP36 gene, is known to be able to end inflammatory responses by directly targeting and ...
leads tofrontierspromotermethylationexpression
https://www.mdpi.com/2072-6643/17/6/1086
Objective: This in vitro study aimed to investigate the impact of folic acid on DNA methylation and gene expression in adipocytes from subcutaneous adipose...
folic aciddna methylationgenomewideimpact
https://zenodo.org/records/10635657
Patients with pancreatic ductal adenocarcinoma (PDAC) have the lowest survival rate among all cancer patients in Europe. Since western societies have the...
multiomicsdeepclusteringreveals
https://www.frontiersin.org/journals/ecology-and-evolution/articles/10.3389/fevo.2021.781498/full
While differences in methylation patterns of ABC transporters under different environmental conditions and their role in plant growth, development, and respo...
dna methylationabc transportersfrontiersdiffersnative
https://www.scirp.org/reference/ReferencesPapers?ReferenceID=2297260
Rall, K., Barresi, G., Walter, M., et al. (2011) A Combination of Transcriptome and Methylation Analyses Reveals Embryologically-Relevant Candidate Genes in...
et alrallkbarresig
https://www.frontiersin.org/journals/oncology/articles/10.3389/fonc.2020.536875/full
Glioblastoma multiforme (GBM) is the most malignant glioma with a high death rate. N6-methyladenosine (m6A) RNA methylation plays an increasingly important r...
rna methylationfrontiersregulatorhnrnpctumorigenesis
https://pentabase.com/product/epidirect-mgmt/
Dec 8, 2025 - EpiDirect® MGMT is a rapid, bisulfite-free qPCR assay using INA® chemistry. Quantifies MGMT methylation in 2 hours from minimal DNA input
mgmtmethylationassay
https://www.illumina.com/products/by-type/microarray-kits/infinium-methylation-epic.html
Robust methylation profiling microarray providing extensive coverage of CpG islands, genes, and enhancers. Ideal for genetic and rare disease research, cancer...
infiniumkitmethylationprofilingarray
https://pubmed.ncbi.nlm.nih.gov/30140739/
Curtailed sleep promotes weight gain and loss of lean mass in humans, although the underlying molecular mechanisms are poorly understood. We investigated the...
sleep lossacuteresultstissuespecific
https://www.osti.gov/pages/biblio/1627274-heterochromatic-genome-stability-requires-regulators-histone-h3-k9-methylation
The U.S. Department of Energy's Office of Scientific and Technical Information
heterochromaticgenomestabilityregulatorshistone
https://pubmed.ncbi.nlm.nih.gov/30644360/?dopt=Abstract
Direct reprogramming of fibroblasts to neurons induces widespread cellular and transcriptional reconfiguration. Here, we characterized global epigenomic...
dna methylationglobalremodelingdirectreprogramming
https://reportorbit.com/how-can-you-support-healthy-methylation/
Oct 31, 2025 - Learn effective ways to support healthy methylation through nutrition, lifestyle habits, and supplements for optimal cellular and overall health.
can yousupporthealthymethylation
https://www.endocrine.org/journals/jcem-case-reports/adrenocortical-tumor-in-kcnj5-and-dna-methylation-of-cyp11b2
The authors present a case of unilateral primary aldosteronism with pathogenic variants in KCNJ5 and suppressed CYP11B2 expression.
adrenocortical tumorpathogenic variantassociateddna
https://pubmed.ncbi.nlm.nih.gov/37702447/
Myocardial fibrosis is an underlying cause of many cardiovascular diseases. Novel insights into the epigenetic control of myocardial fibrosis are now emerging....
myocardial fibrosisinducedmirsuppressionvia
https://pubmed.ncbi.nlm.nih.gov/31288858/
Our study highlighted a strong alteration of the clustered PCDHs methylation pattern in the analysed solid cancers and suggested these methylation aberrations...
methylationalterationscancer
https://www.frontiersin.org/journals/psychiatry/articles/10.3389/fpsyt.2023.1065417/full
ABSTRACTObjective: We explored the DNA methylation and messenger RNA (mRNA) co-expression network and hub genes in first-episode, drug-naive adolescents with...
dna methylationfrontierscoexpressionnetwork
https://pubmed.ncbi.nlm.nih.gov/35798818/
Although substantial progress has been made in managing COVID-19, it is still difficult to predict a patient's prognosis. We explored the epigenetic signatures...
post covidewaspatientsshowsmethylation
https://www.frontiersin.org/journals/plant-science/articles/10.3389/fpls.2016.01675/full
Differences in drought stress tolerance within diverse rice genotypes have been attributed to genetic diversity and epigenetic alterations. DNA methylation i...
dna methylationchanges twofrontiersgenomewide
https://www.frontiersin.org/journals/oncology/articles/10.3389/fonc.2020.01082/full
Aims: Long non-coding RNA IRAIN (lncRNA IRAIN) plays a critical role in numerous malignancies. However, the function of lncRNA IRAIN in renal carcinoma (RC) ...
non coding rnafrontierslongvegfaexpression
https://www.standard.co.uk/lifestyle/health/methylation-diet-food-eat-reduce-ageing-men-b1230107.html
May 28, 2025 - According to a new study foods like garlic, berries, and rosemary may reverse ageing
newstudyfindsmethylationdiet
https://www.mdpi.com/1999-4915/13/7/1415
Protein modifications dynamically occur and regulate biological processes in all organisms. Towards understanding the significance of protein modifications in...
acetylationmethylationallysinemodificationprofile
https://www.frontiersin.org/journals/genetics/articles/10.3389/fgene.2012.00129/full
Growth and maturation of healthy oocytes within follicles requires bidirectional signaling and intercellular gap junctional communication. Aberrant endocrine...
frontierscompromisedfertilitysnrpn
https://www.mendeley.com/catalogue/61a0bea6-4a12-346b-b886-13d275de2cad/
(2022) Smit et al. Scientific Reports. Uveal melanoma (UM) is an aggressive intra-ocular cancer with a strong tendency to metastasize. Metastatic UM is...
genomewideaberrantmethylationpreview
https://pubmed.ncbi.nlm.nih.gov/28473536/
The majority of CpG dinucleotides in the human genome are methylated at cytosine bases. However, active gene regulatory elements are generally hypomethylated...
cytosine methylationimpactdnabindinghuman
https://methprimer.com/
MethPrimer is a free online tool for designing primers for DNA methylation studies using bisulfite-converted DNA.
dna methylationprimer design
https://www.epigendx.online/en/2021/fam19a4/
The method of GLAD-PCR analysis was used to determine the methylation of RCGY sites in the regulatory region of the FAM19A4 gene (Xp3: 68932451 - 68932800) in...
studymethylationsitesregulatory
https://pubmed.ncbi.nlm.nih.gov/25425661/
DNA methylation in Arabidopsis thaliana is maintained by at least four different enzymes: DNA methyltransferase1 (MET1), chromomethylase3 (CMT3), domains...
chromatinremodelerfamilyproteinsrequired
https://www.frontiersin.org/journals/genetics/articles/10.3389/fgene.2021.622233/full
N6-methyladenosine [m(6)A/m6A] methylation is one of the most common RNA modifications in eukaryotic cell mRNA and plays an important regulatory role in mRNA...
rna methylationfrontiersregulatorsactpotential
https://pubmed.ncbi.nlm.nih.gov/21245466/
Plant viruses are excellent tools for studying microbial-plant interactions as well as the complexities of host activities. Our study focuses on the role of C2...
degradationsuppressdna