https://www.epa.gov/pesticide-science-and-assessing-pesticide-risks/acute-oral-toxicity-and-down-procedure
Acute Oral Toxicity Up-And-Down-Procedure | US EPA
Jan 23, 2026 - The Up-and-Down Procedure is an alternative acute toxicity test that provides a way to determine the toxicity of chemicals with fewer test animals by using...
up and down procedureacute oral toxicityusepa