antisense - Robuta Search

https://pmc.ncbi.nlm.nih.gov/articles/PMC25326/ Phosphorothioate Antisense Oligonucleotides Induce the Formation of Nuclear Bodies - PMC Antisense oligonucleotides are powerful tools for the in vivo regulation of gene expression. We have characterized the intracellular distribution of... antisense oligonucleotides nuclear bodies phosphorothioate induce formation https://pmc.ncbi.nlm.nih.gov/articles/PMC7894279/ Hydrocephalus Complicating Intrathecal Antisense Oligonucleotide Therapy for Huntington's Disease -... antisense oligonucleotide hydrocephalus intrathecal therapy huntington https://www.wikidata.org/wiki/Q41088161 Retroviral Vector-Mediated Transfer of an Antisense Cyclin G1 Construct Inhibits Osteosarcoma Tumor... scientific article published on September 20, 1997 https://www.biospace.com/akcea-and-pfizer-inc-announce-licensing-agreement-for-investigative-antisense-therapy-akcea-angptl3-lrx Akcea and Pfizer Inc. Announce Licensing Agreement for investigative antisense therapy... Oct 9, 2019 - Akcea and Ionis to earn $250 million license fee pfizer inc licensing agreement announce https://www.prnewswire.com/news-releases/dynacure-announces-approval-of-clinical-trial-application-for-dyn101-an-antisense-medicine-to-treat-rare-disease-centronuclear-myopathies-300839906.html Dynacure Announces Approval of Clinical Trial Application for DYN101, an Antisense Medicine to... /PRNewswire/ -- Dynacure, a clinical stage drug development company focused on improving the lives of patients with rare and orphan disorders, today... https://www.wikidata.org/wiki/Q68078628 Antisense nonmuscle myosin heavy chain and c-myb oligonucleotides suppress smooth muscle cell... scientific article published on 01 April 1992 myosin heavy chain https://www.prnewswire.com/news-releases/global-antisense-and-rnai-therapeutics-market-report-2021-market-to-reach-1-9-billion-by-2027---us-market-is-estimated-at-331-2-million-while-china-is-forecast-to-grow-at-9-6-cagr-301259628.html Global Antisense and RNAi Therapeutics Market Report 2021: Market to Reach $1.9 Billion by 2027 -... https://www.mdpi.com/1422-0067/22/23/12678 Cold-Inducible RNA-Binding Protein but Not Its Antisense lncRNA Is a Direct Negative Regulator of... Inhibition of the 14q32 microRNAs, miR-329-3p and miR-495-3p, improves post-ischemic neovascularization. Cold-inducible RNA-binding protein (CIRBP) facilitates... https://www.mayo.edu/research/clinical-trials/cls-20566166 Experimental Antisense Oligonucleotide Treatment for Amyotrophic Lateral Sclerosis With an arg15leu... Learn more about services at Mayo Clinic. amyotrophic lateral sclerosis antisense oligonucleotide treatment for experimental https://www.wikidata.org/wiki/Q40573014 Antisense RNA control in bacteria, phages, and plasmids - Wikidata scientific article published on January 1994 antisense rna control bacteria phages plasmids https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2022.898334/full Frontiers | Antisense Oligonucleotide-Based Therapy on miR-181a-5p Alleviates Cartilage Degradation... Temporomandibular joint osteoarthritis (TMJOA) condylar cartilage degeneration and abnormal subchondral bone pathological remodeling induce pain and joint dy... antisense oligonucleotide https://www.ncbi.nlm.nih.gov/gene/100506495 LIFR-AS1 LIFR antisense RNA 1 [Homo sapiens (human)] - Gene - NCBI antisense rna homo sapiens human gene lifr as1 https://www.news-medical.net/news/20120605/Antisense-Pharma-presents-data-from-trabedersen-Phase-III-cancer-study-at-ASCO-2012.aspx Antisense Pharma presents data from trabedersen Phase I/II cancer study at ASCO 2012 Jun 19, 2019 - The biopharmaceutical company Antisense Pharma today presents trabedersen complete data from its clinical Phase I/II study in patients with advanced pancreatic... https://pmc.ncbi.nlm.nih.gov/articles/PMC39822/ Antisense globin RNA in mouse erythroid tissues: structure, origin, and possible function - PMC The aim of the experiments described in this paper was to test for the presence of antisense globin RNA in mouse erythroid tissues and, if found, to... https://www.fiercebiotech.com/keyword/antisense antisense | Fierce Biotech antisense fierce biotech https://www.spandidos-publications.com/10.3892/ijo.15.4.653/abstract MDM2 oncogene as a target for cancer therapy: An antisense approach. International Journal of Oncology is an international journal devoted to oncology research and cancer treatment. as a cancer therapy mdm2 oncogene target https://www.wikidata.org/wiki/Q28240424 Selecting effective antisense reagents on combinatorial oligonucleotide arrays - Wikidata scientific article (publication date: June 1997) selecting effective antisense reagents combinatorial https://www.cancer.gov/publications/dictionaries/cancer-terms/def/antisense-rna Definition of antisense RNA - NCI Dictionary of Cancer Terms - NCI NCI's Dictionary of Cancer Terms provides easy-to-understand definitions for words and phrases related to cancer and medicine. definition of antisense rna nci dictionary cancer https://www.preprints.org/manuscript/202509.1588 Artificial Intelligence-Driven Design of Antisense Oligonucleotides for Precision Medicine in... Rare neuromuscular disorders impose a significant burden on patients, caregivers, and the health care system. However, effective disease-modifying therapies... artificial intelligence design of antisense oligonucleotides precision medicine driven https://www.scirp.org/journal/paperinformation?paperid=22915 Genetic Transformation of Citrus sinensis L. with an antisense ACC oxidase Gene Optimizing embryogenic callus induction, plantlet regeneration, and genetic transformation of Citrus sinensis using Agrobacterium tumefaciens. Successful... genetic transformation citrus sinensis https://www.ncbi.nlm.nih.gov/gene/439931 THAP7-AS1 THAP7 antisense RNA 1 [Homo sapiens (human)] - Gene - NCBI antisense rna homo sapiens human gene thap7 as1 https://www.ncbi.nlm.nih.gov/gene/100132116 ACTA2-AS1 ACTA2 antisense RNA 1 [Homo sapiens (human)] - Gene - NCBI antisense rna homo sapiens human gene acta2 as1 https://pmc.ncbi.nlm.nih.gov/articles/PMC19506/ Intrastriatally injected c-fos antisense oligonucleotide interferes with striatonigral but not... Antisense c-fos oligonucleotides injected into the neostriatum of conscious rats selectively inhibited c-fos expression associated with compensatory increases... c fos antisense oligonucleotide injected https://www.thebusinessresearchcompany.com/report/antisense-and-rnai-therapeutics-global-market-report Antisense and RNAi Therapeutics Market Size Report 2026 market size antisense rnai therapeutics report https://erowid.org/references/refs_view.php?ID=5962&S=Kanthasamy&SField=Author Erowid.org: Erowid Reference 5962 : Unilateral infusion of a dopamine transporter antisense into... The Index page for the reference article: Kanthasamy A, Sprague J, Shotwell J, Nichols D Unilateral infusion of a dopamine transporter antisense into the... erowid org https://www.ncbi.nlm.nih.gov/gene/100507475 IDH1-AS1 IDH1 antisense RNA 1 [Homo sapiens (human)] - Gene - NCBI antisense rna homo sapiens human gene idh1 as1 https://www.preprints.org/manuscript/202303.0389 Improved Prediction of Antisense Oligonucleotide Efficacy for Exon Skipping Using Ensemble Learning... Antisense oligonucleotide (ASO)-mediated exon skipping has become a valuable tool for investigating gene function and developing gene therapy. Machine... antisense oligonucleotide https://www.ncbi.nlm.nih.gov/gene/10984 KCNQ1OT1 KCNQ1 opposite strand/antisense transcript 1 [Homo sapiens (human)] - Gene - NCBI https://www.fiercebiotech.com/research/how-ionis-antisense-drugs-could-work-2-neurodegenerative-diseases How Ionis' antisense drugs could help combat ALS and dementia | Fierce Biotech Sep 2, 2020 - Frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS) are two fatal neurodegenerative diseases marked by different clinical signs. antisense drugs https://www.sciencedaily.com/releases/2011/10/111005131646.htm Antisense therapy delivers long-term correction of severe spinal muscular atrophy in mice |... Scientists have discovered that the devastating neuromuscular disease, spinal muscular atrophy (SMA), might not exclusively affect the motor neurons in the... https://www.ncbi.nlm.nih.gov/gene/100750247 HIF1A-AS2 HIF1A antisense RNA 2 [Homo sapiens (human)] - Gene - NCBI antisense rna homo sapiens human gene hif1a as2 https://www.fiercebiotech.com/biotech/sanofi-inks-400m-biobuck-deal-test-mettle-aloys-antisense-platform Sanofi inks $400M biobucks deal for Alloy's antisense platform Jan 8, 2025 - Sanofi is paying $27.5 million in upfront and near-term fees to use an antisense platform in the development of a central nervous system drug. sanofi inks 400m biobucks deal https://elifesciences.org/articles/02105v1 Tyrosine phosphorylation of RNA Polymerase II CTD is associated with antisense promoter... rna polymerase ii tyrosine phosphorylation https://www.erowid.org/references/refs_view.php?ID=1393 Erowid.org: Erowid Reference 1393 : An antisense oligonucleotide targeted at MAO-B attenuates rat... The Index page for the reference article: Falk EM, Cook VJ, Nichols DE, Sprague JE An antisense oligonucleotide targeted at MAO-B attenuates rat striatal... https://www.nationwidechildrens.org/research/areas-of-research/center-for-gene-therapy/muscular-dystrophy-podcasts/february-2012 Dr. Burghes Discusses Antisense Oligomer Treatment in an SMA Mouse Model: February 2012 Dr. Burghes discusses antisense oligomer treatment in an SMA mouse model. https://www.epo.org/de/boards-of-appeal/decisions/w990010eu1 W 0010/99 (Antisense/BIOGNOSTIK) vom 19.06.2000 19 06 w 0010 99 antisense https://www.researchandmarkets.com/reports/4418441/antisense-therapeutics-ltd-anp-financial-and Antisense Therapeutics Ltd (ANP) - Financial and Strategic SWOT Analysis Review This swot analysis features 5 companies, including Biosensis Pty Ltd, Genetic Technologies Ltd, EnGeneIC Ltd, Clinuvel Pharmaceuticals Ltd, Pharmaxis Ltd antisense therapeutics swot analysis ltd anp financial https://www.ub.edu/ubtv/index.php/en/node/122139 Advances in new animal models of Parkinson's disease through antisense therapies | UBtv parkinson s disease https://www.wikidata.org/wiki/Q42825793 Antisense oligonucleotides suppress cell-volume-induced activation of chloride channels - Wikidata scientific article published on August 1995 antisense oligonucleotides chloride channels suppress cell volume https://www.fiercebiotech.com/biotech/ultragenyx-pauses-antisense-trial-after-patients-lose-ability-to-walk Ultragenyx pauses antisense trial after patients lose ability to walk | Fierce Biotech Oct 27, 2020 - Ultragenyx Pharmaceutical has paused dosing in a phase 1/2 https://www.mdpi.com/1422-0067/25/11/6113 Targeted Antisense Oligonucleotide-Mediated Skipping of Murine Postn Exon 17 Partially Addresses... Periostin, a multifunctional 90 kDa protein, plays a pivotal role in the pathogenesis of fibrosis across various tissues, including skeletal muscle. It... antisense oligonucleotide https://www.ncbi.nlm.nih.gov/gene/750 GAS8-AS1 GAS8 antisense RNA 1 [Homo sapiens (human)] - Gene - NCBI antisense rna homo sapiens human gene as1 ncbi https://www.erowid.org/references/refs_view.php?ID=5962&S=Nichols_D&SField=Author Erowid.org: Erowid Reference 5962 : Unilateral infusion of a dopamine transporter antisense into... The Index page for the reference article: Kanthasamy A, Sprague J, Shotwell J, Nichols D Unilateral infusion of a dopamine transporter antisense into the... erowid org https://www.ncbi.nlm.nih.gov/gene/100874002 OXCT1-AS1 OXCT1 antisense RNA 1 [Homo sapiens (human)] - Gene - NCBI antisense rna homo sapiens human gene oxct1 as1 https://www.prnewswire.com/news-releases/the-global-antisense-and-rnai-therapeutics-market-size-is-expected-to-reach-usd-1-81-billion-by-2025--300797334.html The global antisense and RNAi therapeutics market size is expected to reach USD 1.81 billion by 2025 https://www.news-medical.net/news/20091014/Antisense-Therapeutics-completes-repeat-dosing-toxicology-studies-for-ATL1103.aspx Antisense Therapeutics completes repeat-dosing toxicology studies for ATL1103 Oct 14, 2009 - Antisense Therapeutics Limited is pleased to announce that the Company has now completed repeat-dosing toxicology studies for ATL1103 in two species -- mouse... antisense therapeutics toxicology studies completes repeat dosing https://www.lancaster.ac.uk/people/robertmr/OLD/antisense.html Tomato 14-3-3 antisense plants 14 3 tomato antisense plants https://gitlab.com/uniluxembourg/lcsb/BioCore/minerva/core/-/merge_requests/1751 Resolve "CellDesigner export: missing "type" attribute for gene, rna and antisense rna species... https://www.wikidata.org/wiki/Q34638492 A human beta-actin expression vector system directs high-level accumulation of antisense... https://www.murdoch.edu.au/research/hfi/our-centres/personalised-medicine-centre/molecular-therapy-laboratory/submission-for-antisense-therapeutics Submission for antisense drug development | Health Futures Institute Make a submission for antisense drug development - Molecular Therapy Laboratory antisense drug health futures submission development institute https://pmc.ncbi.nlm.nih.gov/articles/PMC12266137/ Splice-modulating antisense oligonucleotides targeting a pathogenic intronic variant in adult... Adult polyglucosan body disease (APBD) is a rare, adult-onset neurodegenerative disorder caused by loss-of-function variants in the glycogen branching enzyme... antisense oligonucleotides splice modulating targeting https://pmc.ncbi.nlm.nih.gov/articles/PMC6415796/ Self-assembly into nanoparticles is essential for receptor mediated uptake of therapeutic antisense... Antisense oligonucleotides (ASOs) have the potential to revolutionize medicine due to their ability to manipulate gene function for therapeutic purposes. ASOs... https://www.mdpi.com/1422-0067/24/3/2697 Application of Antisense Conjugates for the Treatment of Myotonic Dystrophy Type 1 Myotonic dystrophy type 1 (DM1) is one of the most common muscular dystrophies and can be potentially treated with antisense therapy decreasing mutant DMPK,... for the myotonic dystrophy application antisense conjugates https://elifesciences.org/articles/01849/figures Figures and data in Natural antisense transcripts regulate the neuronal stress response and... The mRNA that encodes a Drosophila sodium channel enables neurons to adapt to acute temperature changes, via a mechanism independent of its protein-coding role. in natural https://www.wikidata.org/wiki/Q24561620 Expression of an antisense prosystemin gene in tomato plants reduces resistance toward Manduca... https://pmc.ncbi.nlm.nih.gov/articles/PMC44188/ Partial rescue of a lethal phenotype of fragile bones in transgenic mice with a chimeric antisense... Previously, transgenic mice were prepared that developed a lethal phenotype of fragile bones because they expressed an internally deleted mini-gene for the pro... https://www.ncbi.nlm.nih.gov/gene/100507308 TARID TCF21 antisense RNA inducing promoter demethylation [Homo sapiens (human)] - Gene - NCBI antisense rna https://pmc.ncbi.nlm.nih.gov/articles/PMC8410092/ Antisense oligonucleotide treatment rescues UBE3A expression and multiple phenotypes of an Angelman... Angelman syndrome (AS) is a severe neurodevelopmental disorder for which only symptomatic treatment with limited benefits is available. AS is caused by... antisense oligonucleotide https://www.researchandmarkets.com/reports/5887255/antisense-and-rnai-therapeutics-market-global Antisense & RNAi Therapeutics Market - Global Forecast 2026-2032 antisense rnai therapeutics market global https://www.ub.edu/ubtv/index.php/video/advances-in-new-animal-models-of-parkinsons-disease-through-antisense-therapies Advances in new animal models of Parkinson's disease through antisense therapies | UBtv parkinson s disease https://www.cancer.gov/publications/dictionaries/cancer-drug/def/antisense-oligonucleotide-qr-313 Definition of antisense oligonucleotide QR-313 - NCI Drug Dictionary - NCI Find technical definitions and synonyms by letter for drugs/agents used to treat patients with cancer or conditions related to cancer. Each entry includes... definition of antisense oligonucleotide qr 313 nci https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2024.1481937/full Frontiers | Characterizing the plasma protein binding profiles of chemistry diversified antisense... IntroductionPlasma protein binding plays a significant role in influencing the pharmacokinetic and pharmacodynamic properties of drugs. This study focuses on... plasma protein binding frontiers https://www.dutchantisense.org/ Dutch Antisense Therapeutics Symposium The Dutch Antisense Therapeutics Symposium is a platform to strengthen the antisense oligonucleotide research in The Netherlands antisense therapeutics dutch symposium https://pmc.ncbi.nlm.nih.gov/articles/PMC5271482/ Therapeutic Potential of Tricyclo-DNA antisense oligonucleotides - PMC Oligonucleotide therapeutics hold great promise for the treatment of various diseases and the antisense field is constantly gaining interest due to the... dna antisense therapeutic potential tricyclo oligonucleotides https://www.mdpi.com/1422-0067/16/2/3251 Neighboring Gene Regulation by Antisense Long Non-Coding RNAs Antisense transcription, considered until recently as transcriptional noise, is a very common phenomenon in human and eukaryotic transcriptomes, operating in... gene regulation non coding neighboring antisense long https://pmc.ncbi.nlm.nih.gov/articles/PMC9940817/ Considerations in the Preclinical Assessment of the Safety of Antisense Oligonucleotides - PMC The nucleic acid therapeutics field has made tremendous progress in the past decades. Continuous advances in chemistry and design have led to many successful... in the antisense oligonucleotides considerations preclinical assessment https://pmc.ncbi.nlm.nih.gov/articles/PMC7355792/ Antisense Oligonucleotides: An Emerging Area in Drug Discovery and Development - PMC Antisense oligonucleotides (ASOs) bind sequence specifically to the target RNA and modulate protein expression through several different mechanisms. The ASO... antisense oligonucleotides drug discovery emerging area https://www.ncbi.nlm.nih.gov/gene/150147 UMODL1-AS1 UMODL1 antisense RNA 1 [Homo sapiens (human)] - Gene - NCBI umodl1 as1 antisense rna homo sapiens human gene ncbi https://pmc.ncbi.nlm.nih.gov/articles/PMC41942/ Exit from G0 and entry into the cell cycle of cells expressing p21Sdi1 antisense RNA - PMC p21Sdi1 (also known as Cip1 and Waf1), an inhibitor of DNA synthesis cloned from senescent human fibroblasts, is an inhibitor of G1 cyclin-dependent kinases... https://elifesciences.org/articles/01849/peer-reviews Peer review in Natural antisense transcripts regulate the neuronal stress response and excitability... The mRNA that encodes a Drosophila sodium channel enables neurons to adapt to acute temperature changes, via a mechanism independent of its protein-coding role. https://www.ncbi.nlm.nih.gov/nuccore/NR_027274.1 Homo sapiens SRRM2 antisense RNA 1 (SRRM2-AS1), transcript variant 1, - Nucleotide - NCBI homo sapiens antisense rna transcript variant srrm2 https://www.ncbi.nlm.nih.gov/nuccore/NR_024166.1 Homo sapiens ZNF205 antisense RNA 1 (ZNF205-AS1), transcript variant 1 - Nucleotide - NCBI homo sapiens antisense rna transcript variant https://pmc.ncbi.nlm.nih.gov/articles/PMC10690781/ Antisense oligonucleotides: a novel Frontier in pharmacological strategy - PMC Antisense oligonucleotides (ASOs) are short single stranded synthetic RNA or DNA molecules, whereas double-stranded RNA nucleotide sequences are called small... antisense oligonucleotides novel frontier pharmacological strategy https://pmc.ncbi.nlm.nih.gov/articles/PMC11551783/ Antisense oligonucleotides as a precision therapy for developmental and epileptic encephalopathies... Developmental and epileptic encephalopathies (DEEs) comprise a complex spectrum of neurological disorders characterized by neurodevelopmental delay and... antisense oligonucleotides precision https://www.ncbi.nlm.nih.gov/gene/285943 HOXA-AS2 HOXA cluster antisense RNA 2 [Homo sapiens (human)] - Gene - NCBI antisense rna homo sapiens human gene hoxa as2 https://www.cancer.gov/publications/dictionaries/cancer-terms/def/bcl-2-antisense-oligodeoxynucleotide-g3139 Definition of bcl-2 antisense oligodeoxynucleotide G3139 - NCI Dictionary of Cancer Terms - NCI NCI's Dictionary of Cancer Terms provides easy-to-understand definitions for words and phrases related to cancer and medicine. definition of bcl 2 antisense