Robuta

https://www.ncbi.nlm.nih.gov/Structure/pdb/5T1U 5T1U: Aminomethyl-Derived Beta Secretase (BACE1) Inhibitors: Engaging Gly230 without an Anilide... beta secretase https://www.ncbi.nlm.nih.gov/gene/23621 BACE1 beta-secretase 1 [Homo sapiens (human)] - Gene - NCBI beta secretase 1 homo sapiens human gene bace1 ncbi https://www.rcsb.org/structure/5DQC RCSB PDB - 5DQC: Co-crystal of BACE1 with compound 0211 Co-crystal of BACE1 with compound 0211 rcsb pdb co crystal bace1 compound 0211 https://www.growkudos.com/publications/10.4155%25252Fbio-2017-0003/reader Simultaneous Quantitation of The Bace1 Inhibitor Azd3293 and its Metabolite Az13569724 in Human... We report here the bioanalytical methods that were developed and validated to simultaneously quantify AZD3293, a novel BACE1 inhibitor in late-stage... https://www.rcsb.org/structure/4JPC RCSB PDB - 4JPC: Spirocyclic Beta-Site Amyloid Precursor Protein Cleaving Enzyme 1 (BACE1)... Spirocyclic Beta-Site Amyloid Precursor Protein Cleaving Enzyme 1 (BACE1) Inhibitors amyloid precursor protein https://www.rcsb.org/structure/2P83 RCSB PDB - 2P83: Potent and selective isophthalamide S2 hydroxyethylamine inhibitor of BACE1 Potent and selective isophthalamide S2 hydroxyethylamine inhibitor of BACE1 rcsb pdb https://www.rcsb.org/structure/3UQX RCSB PDB - 3UQX: Crystal structure of BACE1 with its inhibitor Crystal structure of BACE1 with its inhibitor rcsb pdb crystal structure bace1 inhibitor https://www.rcsb.org/structure/6WNY RCSB PDB - 6WNY: Crystal structure of BACE1 in complex with (Z)-fluoro-olefin containing compound 15 Crystal structure of BACE1 in complex with (Z)-fluoro-olefin containing compound 15 https://www.rcsb.org/structure/4XXS RCSB PDB - 4XXS: Crystal structure of BACE1 with a pyrazole-substituted tetrahydropyran thioamidine Crystal structure of BACE1 with a pyrazole-substituted tetrahydropyran thioamidine https://www.ebi.ac.uk/chembl/explore/document/CHEMBL3259716 Document: The evolution of amidine-based brain penetrant BACE1 inhibitors. (CHEMBL3259716) - ChEMBL Report card for Document The evolution of amidine-based brain penetrant BACE1 inhibitors. (CHEMBL3259716). Bioorg Med Chem Lett, Beta site amyloid precursor... the evolution https://www.ncbi.nlm.nih.gov/Structure/pdb/3S7L 3S7L: Pyrazolyl And Thienyl Aminohydantoins As Potent Bace1 Inhibitors BETA-SECRETASE 1(5s)-2-amino-5-(1-ethyl-1h-pyrazol-4-yl)-3-methyl-5-[3-(pyrimidin-5-yl)phenyl]-3,5-dihydro-4h-imidazol-4-oneWay-256591 thienyl potent bace1 inhibitors https://www.ncbi.nlm.nih.gov/Structure/pdb/6JSF 6JSF: Crystal Structure of BACE1 in complex with... Beta-secretase 1DIMETHYL SULFOXIDEIODIDE... crystal structure bace1 complex