Robuta

https://www.prnewswire.com/news-releases/phase-1a1b-study-results-of-akesos-pd-1ctla-4-bispecific-antibody-published-in-cell-reports-medicine-highlighting-promising-efficacy-in-solid-tumors-refractoryrelapsed-to-standard-therapy-301961659.html
/PRNewswire/ -- Akeso (9926. HK) announced the publication of the phase 1a/1b first-in-human study (COMPASSION-01) evaluating cadonilimab (PD-1/CTLA-4...
study resultsphaseakesopd
https://www.businesswire.com/news/home/20251110761345/en/Belenos-Pipeline-Updates-First-Clinical-Data-from-Lead-Asset-BEL512-a-Long-lasting-Bispecific-Targeting-TSLP-and-IL-13-Second-Asset-BEL536-a-First-in-class-Long-acting-Bispecific-Targeting-OX40L-and-IL-13-Phase-1-to-Start-1Q2026
Belenos Biosciences Inc.: BEL512: Support for Extended Dosing Intervals: Subcutaneous BEL512 (CM512) demonstrated long half-life of up to 70 days Clinical Im...
clinical databelenospipelineupdatesfirst
https://www.newsfilecorp.com/release/280455/Global-Development-Accelerates-Leads-Biolabs-PDL141BB-Bispecific-Antibody-Granted-Fast-Track-Designation-by-FDA
Nanjing, China--(Newsfile Corp. - January 15, 2026) - Nanjing Leads Biolabs Co., Ltd. (HKE: 9887) ("Leads Biolabs" or the "Company")...
global developmentleadspdbispecific
https://www.bioworld.com/articles/727134-bispecific-sirna-knocks-down-yap1-wwtr1-with-single-guide-strand?v=preview
Yes-associated protein (YAP), encoded by Yes1-associated transcriptional regulator (YAP1) and transcriptional coactivator with PDZ-binding motif (TAZ), encoded...
guide strandbispecificsirnaknockssingle
https://www.precedenceresearch.com/press-release/bispecific-antibody-therapeutics-contract-manufacturing-market
The bispecific antibody therapeutics contract manufacturing market revenue surpassed USD 9.82 billion in 2025 and is predicted to attain around USD 218.92...
bispecific antibodycontract manufacturingmarket growththerapeuticsinsights
https://www.pharmaceutical-technology.com/news/pfizer-3sbio-deal/
Pfizer has signed a worldwide licensing agreement, excluding China, with biopharmaceutical company 3SBio for SSGJ-707.
global licensingbispecific antibodypfizersignsdeal
https://clarivate.com/life-sciences-healthcare/report/sptoon0011-2023-biopharma-bispecific-therapies-special-topics-special-topics-bispecific-therapies-g7-and-china/
Bispecific therapies represent a class of drug with two binding sites directed at two different antigens or epitopes. This dual action makes bispecific...
special topicsbispecifictherapies
https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2022.1063002/full
Bispecific antibodies (BsAbs) form an exciting class of bio-therapeutics owing to their multispecificity. Although numerous formats have been developed, gene...
bispecific antibodiesfrontiersgenerationstructureguided
https://pubmed.ncbi.nlm.nih.gov/18546289/?ordinalpos=2&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum
Trifunctional bispecific antibodies can efficiently mediate tumor cell killing by redirecting T cells and immune accessory cells to the tumor cell. Here, we...
bispecific antibodynovelx
https://www.pharmacytimes.com/view/pharmacists-play-an-essential-role-in-bispecific-therapy-for-multiple-myeloma
Pharmacists also navigate the REMS program and monitor and manage adverse effect profiles associated with bispecifics.
bispecific therapypharmacistsplayessentialrole
https://www.biospace.com/press-releases/bispecific-antibody-drug-conjugates-in-oncology
antibody drug conjugatesbispecificoncologybiospace
https://dedhamgroup.com/how-bispecific-antibody-therapies-are-impacting-community-practices-and-three-trends-to-watch/
Jan 9, 2025 - Learn how manufacturers can drive adoption of bispecific antibody therapies.
bispecific antibodycommunity practicestherapiesthree
https://www.biospace.com/akeso-announces-launch-of-u-s-investigator-initiated-study-of-cadonilimab-pd-1-ctla-4-bispecific-antibody
Today, Akeso, Inc. (9926.HK) announced that the company will support an investigator-initiated study (IIS) to evaluate the efficacy and safety of Akeso's...
investigator initiated studyakesoannounceslaunch
https://aptevotherapeutics.com/
biotechnology companytherapeuticsclinicalstagefocused
https://www.bruker.com/pl/news-and-events/webinars/2022/phase-appropriate-lc-ms-strategy.html
phaseappropriatelcmsstrategy
https://www.pharmaceutical-technology.com/data-insights/xencor-gets-grant-for-bispecific-antibody-for-treating-gpc3-associated-cancers/
Discover Xencor Inc's groundbreaking patent for novel GPC3 binding domains and bispecific antibodies targeting GPC3-associated cancers. Explore the innovative...
bispecific antibodyxencorincfilespatent
https://www.slideserve.com/tamera/effectiveness-of-bispecific-cytotoxin-dtegfatf-in-ameliorating-human-glioblastoma-tumors
This research by Travis Spangler (2008-2009) investigates the potential effectiveness of the bispecific cytotoxin DTEGFATF in targeting and ameliorating...
pptefficacybispecificcytotoxintreating
https://www.cancer.gov/publications/dictionaries/cancer-drug/def/anti-egfr-anti-4-1bb-bispecific-antibody-hlx35
Find technical definitions and synonyms by letter for drugs/agents used to treat patients with cancer or conditions related to cancer. Each entry includes...
bispecific antibodydefinitionegfr
https://www.pharmaceutical-technology.com/news/biocytogen-radiance-drug/
Biocytogen Pharmaceuticals and Radiance Biopharma have signed an exclusive option and licence agreement for a BsADC.
antibody drug conjugatebiocytogenradiancepartnerbispecific
https://www.bruker.com/de/news-and-events/webinars/2022/phase-appropriate-lc-ms-strategy.html
phaseappropriatelcmsstrategy
https://www.openpr.com/news/4360650/leads-biolabs-pd-l1-4-1bb-bispecific-antibody-opamtistomig
Press release - Getnews - Leads Biolabs' PD-L1/4-1BB Bispecific Antibody Opamtistomig (LBL-024) Earns EU Orphan Drug Designation-Potential First-in-Class...
bispecific antibodyleadspd
https://www.mskcc.org/news/new-extramedullary-myeloma-treatment-with-bispecific-antibodies-improves-survival-dramatically
Read about a new treatment combining bispecific antibodies that is effective against extramedullary myeloma.
bispecific antibodiesnewextramedullarymyelomatreatment
https://pubmed.ncbi.nlm.nih.gov/37490053/
Effector T cells need to form immunological synapses (IS) with recognized target cells to elicit cytolytic effects. Facilitating IS formation is the principal...
population dynamicsimmunological synapseformationinducedbispecific
https://www.rcsb.org/structure/8TI4
monovalent bispecific IgG antibodies through novel electrostatic steering mutations at the CH1-CL interface
rcsb pdbigg antibodiesmonovalentbispecificnovel
https://aijourn.com/bispecific-antibodies-market-industry-global-forecasts-and-key-players-to-2035-over-400-bispecific-antibody-candidates-under-research-worldwide-researchandmarkets-com/
DUBLIN--(BUSINESS WIRE)--The "Bispecific Antibodies Market Industry Trends and Global Forecasts to 2035: By Therapeutic Area, Mechanism of Action, Target
bispecific antibodiesmarket industrykey playersglobalforecasts
https://www.jonesday.com/en/practices/experience/2024/10/bambusa-therapeutics-develops-global-patent-portfolios-for-bispecific-antibodies-to-treat-immunological-and-inflammatory
Jones Day represents Bambusa Therapeutics, Inc. in developing global patent portfolios related to various bispecific antibodies for the treatment of...
bambusa therapeuticspatent portfoliosbispecific antibodiesdevelopsglobal
https://www.biospace.com/press-releases/oncoc4-announces-fda-clearance-of-ind-application-for-potential-best-in-class-pd-1-vegf-bispecific-ai-081-in-advanced-solid-tumors
fda clearanceannouncesindapplicationpotential
https://www.businesswire.com/news/home/20250107874851/en/Biocytogen-and-Acepodia-Join-Forces-to-Advance-Bispecific-Antibody-and-Dual-Payload-ADCs-for-Treating-Complex-Tumors
Biocytogen (HKEX: 02315) and Acepodia (6976:TT), today announced a groundbreaking strategic partnership to jointly assess a dual-payload bispecific antibody-...
join forcesbispecific antibodybiocytogenadvance
https://www.jnj.com/innovativemedicine/emea/janssen-presents-first-results-dual-bispecific-combination-study-showing-96-percent-overall-response
first resultsjanssenpresentsdualbispecific