Robuta

A Role for Heme and Iron in Calcific Aortic Valve Disease?

Heme oxygenase1-(2-METHOXY-ETHOXY)-2-{2-[2-(2-METHOXY-ETHOXY]-ETHOXY}-ETHANE

Creating transformational medicines by unlocking the biology of heme.

Nitric oxide synthase, brain5,6,7,8-TETRAHYDROBIOPTERIN7-[({[4-(dimethylamino)phenyl]methyl}amino)methyl]quinolin-2-amineACETATE IONPROTOPORPHYRIN IX...

NITRIC OXIDE SYNTHASE, BRAIN4-methyl-6-(2-(5-(1-methylpiperidin-4-yl)pyridin-3-yl)ethyl)pyridin-2-amine5,6,7,8-TETRAHYDROBIOPTERINACETATE IONPROTOPORPHYRIN IX...

Heme oxygenase 1 (HO-1), encoded by the HMOX-1 gene, is the main heme oxygenase that catalyzes the degradation of heme into iron, carbon monoxide, and...

The transcriptional factor Bach1 forms a heterodimer with small Maf family, and functions as a repressor of the Maf recognition element (MARE) in vivo. To...

Nitric oxide synthase, brain5,6,7,8-TETRAHYDROBIOPTERIN7-{[(3-fluorophenyl)amino]methyl}quinolin-2-aminePROTOPORPHYRIN IX CONTAINING FEZINC ION

Nitric oxide synthase,...

The nuclear receptors REV-ERBalpha (encoded by NR1D1) and REV-ERBbeta (NR1D2) have remained orphans owing to the lack of identified physiological ligands. Here...

Nitric oxide synthase,...

Regulation of soluble guanylate cyclase (sGC), the primary NO receptor, is linked to NO binding to the prosthetic heme group. Recent studies have demonstrated...

Nitric oxide synthase, brain5,6,7,8-TETRAHYDROBIOPTERIN6-(2-{5-[2-(dimethylamino)ethyl]-2,3-difluorophenyl}ethyl)pyridin-2-amineGLYCEROLPROTOPORPHYRIN IX...

heme oxygenase (biliverdin-producing)PROTOPORPHYRIN IX CONTAINING CO

The growing data obtained from in vivo studies and clinical trials demonstrated the benefit of adult stem cells transplantation in diabetes; although an impo...

These results demonstrate that FIR therapy exerts a potent antiinflammatory effect via the induction of HO-1. The ability of FIR therapy to inhibit...

Structure of rat neuronal nitric oxide synthase heme domain in complex with 7-(3-(Aminomethyl)-4-isopropoxyphenyl)-4-methylquinolin-2-amine

Nitric oxide synthase, brain4-(2-{[(2-amino-4-methylquinolin-7-yl)methyl]amino}ethyl)benzonitrile5,6,7,8-TETRAHYDROBIOPTERINACETATE IONPROTOPORPHYRIN IX...

BOVINE ENDOTHELIAL NITRIC OXIDE SYNTHASE HEME3-BROMO-7-NITROINDAZOLEACETATE IONCACODYLIC ACIDGLYCEROLPROTOPORPHYRIN IX CONTAINING FEZINC ION