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Multi-radionuclide single-photon emission computed tomography (SPECT) is becoming increasingly important in nuclear medicine investigations for... https://pubmed.ncbi.nlm.nih.gov/20624122/?dopt=Abstract Targeting DLL4 in tumors shows preclinical activity but potentially significant toxicity Evaluation of: Yan M, Callahan CA, Beyer JC et al.: Chronic DLL4 blockade induces vascular neoplasms. Nature 463, E6-E7 (2010). 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