caspase - Robuta Search

https://digital.library.adelaide.edu.au/items/04be267c-b35f-4fd2-8790-b52b9e8af7ab Caspase-2 protocols Caspase-2 has been shown to function in apoptosis and in some non-apoptotic pathways, including tumor suppression and aging. Caspase-2 has some unique features... caspase protocols https://data.mendeley.com/datasets/xftzrbsbxx/1 Data for: LL-37-induced caspase-independent apoptosis is associated with plasma membrane... Protein expression data for full length and cleaved PARP and caspase-3, respectively, determined by western blot. GAPDH or histone H3 are included as internal... https://pubmed.ncbi.nlm.nih.gov/38155908/ Boswellia carterii oleoresin extracts induce caspase-mediated apoptosis and G1 cell cycle arrest in... https://nrc-publications.canada.ca/eng/view/object/?id=186957dd-a88f-4b33-a281-6d693c13cc2b Caspase-8-mediated intracellular acidification precedes mitochondrial dysfunction in... Caspase-8-mediated intracellular acidification precedes mitochondrial dysfunction in somatostatin-induced apoptosis mitochondrial dysfunction caspase mediated intracellular acidification https://pubchem.ncbi.nlm.nih.gov/bioassay/1117766 AID 1117766 - Induction of apoptosis in human A549 cells assessed as caspase-3 activation at 1 uM... BioAssay record AID 1117766 submitted by ChEMBL: Induction of apoptosis in human A549 cells assessed as caspase-3 activation at 1 uM after 24 hrs by... https://www.ncbi.nlm.nih.gov/gene/114769 CARD16 caspase recruitment domain family member 16 [Homo sapiens (human)] - Gene - NCBI family member https://phytochem.nal.usda.gov/activity-caspase-3-inhibitor Biological Activity Caspase-3-Inhibitor | Dr. Duke's Phytochemical and Ethnobotanical Databases biological activity https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2017.00988/full Frontiers | Gleditsia Saponin C Induces A549 Cell Apoptosis via Caspase-Dependent Cascade and... Saponins are natural compounds and possess the most promising anti-cancer function. Here, a saponin gleditsia saponin C (GSC), extracted from gleditsiae fruc... https://discovery.fiu.edu/display/pub207706 Small-Molecule XIAP Antagonist Restores Caspase-9-Mediated Apoptosis in XIAP-Positive Diffuse Large... https://pubchem.ncbi.nlm.nih.gov/protein/A0A3Q1LN50 Apoptosis and caspase activation inhibitor (cattle) | Protein Target - PubChem Protein target information for Apoptosis and caspase activation inhibitor (cattle). Find diseases associated with this biological target and compounds tested... apoptosis caspase activation inhibitor cattle https://pubchem.ncbi.nlm.nih.gov/bioassay/1786666 AID 1786666 - CASPASE-6_CE Eurofins SafetyScreen44 (BI) - PubChem BioAssay record AID 1786666 submitted by ChEMBL: CASPASE-6_CE Eurofins SafetyScreen44 (BI). aid caspase ce eurofins bi https://dukespace.lib.duke.edu/items/2449ad14-e635-447d-b87d-ea67e1be71df The Role and Regulation of Caspase-2 in Lipoapoptosis the role regulation caspase https://biblio.ugent.be/publication/444461 Caspase-14 is a crucial protease in proper stratum corneum formation is a caspase crucial https://pubchem.ncbi.nlm.nih.gov/bioassay/463117 AID 463117 - HTS to identify inhibitors of Caspase inhibitor (zVAD) Induced Cell Death in L929... BioAssay record AID 463117 submitted by University of Pittsburgh Molecular Library Screening Center: HTS to identify inhibitors of Caspase inhibitor (zVAD)... https://scholars.uky.edu/en/publications/neuroprotection-of-grafted-neurons-with-a-gdnfcaspase-inhibitor-c/ Neuroprotection of grafted neurons with a GDNF/caspase inhibitor cocktail - University of Kentucky with a https://tobias-lib.ub.uni-tuebingen.de/xmlui/handle/10900/121857 Apoptotic stress induces Bax-dependent, caspase-independent redistribution of LINC complex nesprins https://pubchem.ncbi.nlm.nih.gov/bioassay/1306958 AID 1306958 - Induction of apoptosis in human MCF7 cells assessed as caspase 9 cleavage at 8.27 uM... BioAssay record AID 1306958 submitted by ChEMBL: Induction of apoptosis in human MCF7 cells assessed as caspase 9 cleavage at 8.27 uM after 48 hrs by Western... https://inventions.techventures.columbia.edu/technologies/specific-inhibition-of-caspase--CU12019 Specific inhibition of caspase-2 activation for the treatment of neurodegenerative diseases Membrane-penetrable hexapeptide selectively blocks caspase-2-RAIDD, halting neuron death for neurodegenerative therapies. for the specific inhibition caspase https://pubchem.ncbi.nlm.nih.gov/bioassay/909 AID 909 - Concentration-Response Counterscreen for Redox Active Inhibitors of Caspase-7: Catalase -... BioAssay record AID 909 submitted by National Center for Advancing Translational Sciences (NCATS): Concentration-Response Counterscreen for Redox Active... https://www.ophth.wisc.edu/blog/2009/10/01/fak-and-p38-map-kinase-dependent-activation-of-apoptosis-and-caspase-3-in-retinal-endothelial-cells-by-alpha1ivnc1/ FAK and p38-MAP kinase-dependent activation of apoptosis and caspase-3 in retinal endothelial cells... PubMed ID: 19443723 Author(s): Boosani CS, Nalabothula N, Munugalavadla V, Cosgrove D, Keshamoun VG, Sheibani N, Sudhakar A. FAK and p38-MAP kinase-dependent... https://experts.umn.edu/en/publications/bcl-2caspase-3-mucosal-imbalance-favors-t-cell-resistance-to-apop/ Bcl-2/Caspase 3 mucosal imbalance favors T cell resistance to apoptosis in dogs with inflammatory... https://www.frontiersin.org/journals/oncology/articles/10.3389/fonc.2022.861709/full Frontiers | Caspase-8: Friend or Foe in Bortezomib/Lenalidomide-Based Therapy for Myeloma Antiproliferation and proapoptosis are two major molecular mechanisms of action of drugs used for the treatment of multiple myeloma. Proteasome inhibitors. s... friend or foe https://pubchem.ncbi.nlm.nih.gov/protein/3NS7_A Chain A, Caspase-1 (human) | Protein Target - PubChem Protein target information for Chain A, Caspase-1 (human). Find diseases associated with this biological target and compounds tested against it in bioassay... human protein chain caspase target pubchem https://nrc-publications.canada.ca/eng/view/object/?id=7a6887cc-120e-4390-be23-dba7dad1642c Neither caspase-3 nor DNA fragmentation factor are required for high molecular weight DNA... Neither caspase-3 nor DNA fragmentation factor are required for high molecular weight DNA degradation in apoptosis https://digitalcommons.usf.edu/etd/433/ "BRCA1 185delAG Mutant Protein, BRAt, Amplifies Caspase-Mediated Apopto" by Joshua D. O'Donnell Ovarian cancer is a deadly disease that kills an estimated 15,000 women annually in the United States. It is estimated that approximately 10% of ovarian... https://hsrc.himmelfarb.gwu.edu/smhs_path_facpubs/845/ "Inhibition of Fas receptor (CD95)-induced hepatic caspase activation a" by Judy A. Lawson, Michael... The mechanism of liver cell injury induced by an overdose of the analgesic acetaminophen (AAP) remains controversial. Recently, it was hypothesized that a... https://pubmed.ncbi.nlm.nih.gov/12957569/?dopt=Abstract Measuring T cell-mediated cytotoxicity using fluorogenic caspase substrates Cytotoxic T lymphocytes (CTLs) play a major role in the immune response against viruses and other intracellular pathogens. In addition, CTLs are implicated in... t cell measuring mediated cytotoxicity using https://pubmed.ncbi.nlm.nih.gov/16274926/ Quercetin arrests G2/M phase and induces caspase-dependent cell death in U937 cells Quercetin, a natural product derived from grapes, has been shown to prevent carcinogenesis in murine models. We report here that quercetin induces... https://inventions.pitt.edu/technologies/caspase-3-knockout-colon--03687 Caspase-3 Knockout Colon Cancer Cells Caspase-3 knockout HCT116 cells via AAV targeting offer a unique, reliable cancer apoptosis model for drug screening and research. colon cancer caspase knockout cells https://www.thermofisher.com/antibody/product/Caspase-1-Antibody-Polyclonal/PA5-87536 Caspase 1 Polyclonal Antibody | Invitrogen (PA5-87536) Detect Caspase 1 in WB, IHC (P), ICC/IF, IHC, ELISA. Reacts with Rabbit, Mouse, Rat. Cited in 9 publications. Catalog # PA5-87536 polyclonal antibody caspase invitrogen https://www.biochemie.abi.med.uni-muenchen.de/publications/article/pub_2004_020.html Phosphorylation of presenilin 1 at the caspase recognition site regulates its proteolytic... at the https://scholars.duke.edu/publication/780062 Scholars@Duke publication: Caspase-mediated cleavage of HuR in the cytoplasm contributes to... https://www.biologyconference.com/ Mechanisms of Caspase Activation and Inhibition mechanisms caspase activation inhibition https://scholarshare.temple.edu/items/f9c72248-3fc4-4e10-a31f-4df6f987cbdf PROATHEROGENIC LIPIDS INCREASE CASPASE-1 NUCLEAR LOCALIZATION IN HUMAN AORTIC ENDOTHELIAL CELLS It is well established that cytosolic caspase-1 activation, mediated by inflammasome after pathogens-associated molecular patterns (PAMP) and metabolic... https://www.ncbi.nlm.nih.gov/Structure/cdd/cd08341 CDD Conserved Protein Domain Family: DED_Caspase_10_r1 cd08341 (PSSM ID: 260047): Conserved Protein Domain Family DED_Caspase_10_r1, Death effector domain (DED) found in caspase-10, repeat 1 cdd protein domain family ded https://www.ncbi.nlm.nih.gov/Structure/pdb/4EHL 4EHL: Allosteric Modulation of Caspase-3 through Mutagenesis ACE-ASP-GLU-VAL-ASP-CHLOROMETHYLKETONE INHIBITORCaspase-3 allosteric modulation caspase mutagenesis https://www.sfb-trr167.uni-freiburg.de/publications/the-caspase-activated-dnase-drives-inflammation-and-contributes-to-defense-against-viral-infection/ The Caspase-Activated DNase drives inflammation and contributes to defense against viral infection... https://www.ideals.illinois.edu/items/107431 Characterization of the vaccinia virus M1 protein on caspase inhibition and the MVA/5.2KB virus on... https://vivo.colorado.edu/display/meshid_D12.776.476.075.405.550.100 Proteins - Caspase 1 | CU Experts | CU Boulder proteins caspase cu experts boulder https://pubmed.ncbi.nlm.nih.gov/25794010/ ENTPD5 induces apoptosis in lung cancer cells via regulating caspase 3 expression This study is to investigate the relationship between ectonucleoside triphosphate diphosphohydrolase 5 (ENTPD5) expression and lung cancer clinicopathological... lung cancer https://www.thermofisher.com/antibody/product/Caspase-1-p20-Antibody-Polyclonal/BS-10442R Caspase-1 p20 Polyclonal Antibody (BS-10442R) Detect Caspase-1 p20 in ELISA, Flow, ICC/IF, IHC (F), IHC (P). Reacts with Rabbit. Catalog # BS-10442R polyclonal antibody caspase bs https://repository.lib.ncsu.edu/items/e0bcf723-b1b3-48bd-b5ee-0ae294f94c9f/full Allosteric Inactivation of Caspase-3 Without Major Loop Rearrangements: Properties of the Inactive... https://journals.plos.org/plosone/article/authors?id=10.1371/journal.pone.0101579 Thymoquinone Induces Cell Death in Human Squamous Carcinoma Cells via Caspase Activation-Dependent... Background Thymoquinone (TQ), an active component of Nigella sativa or black cumin, elicits cytotoxic effects on various cancer cell lines. However, the... https://researchprofiles.ku.dk/en/publications/crystal-structures-of-human-caspase-6-reveal-a-new-mechanism-for-/ Crystal structures of human caspase 6 reveal a new mechanism for intramolecular cleavage... https://publications-cnrc.canada.ca/fra/voir/objet/?id=01051b94-e375-49d2-9d21-69e94a151c87 Increased expression of E2F1 during dopamine-evoked caspase-3-mediated apoptosis in rat cortical... Increased expression of E2F1 during dopamine-evoked caspase-3-mediated apoptosis in rat cortical neurons https://publications-cnrc.canada.ca/eng/view/object/?id=ee25ba4f-9ff7-4fd9-b519-01526b1be94b E2F1 modulates caspase-3-dependent neuronal apoptosis and contributes to neuronal injury following... E2F1 modulates caspase-3-dependent neuronal apoptosis and contributes to neuronal injury following cerebral ischemia https://www.frontiersin.org/journals/oncology/articles/10.3389/fonc.2022.981332/full Frontiers | Caspase activation counteracts interferon signaling after G2 checkpoint abrogation by... Recent studies suggest that inhibition of the ATR kinase can potentiate radiation-induced antitumor immune responses, but the underlying mechanisms and their... frontiers caspase activation interferon https://oru.diva-portal.org/smash/record.jsf?pid=diva2:1336805 Effect of Staphylococcus aureus on the NLRP3 inflammasome, caspase-1 and IL-1 Beta expression in... https://pubmed.ncbi.nlm.nih.gov/16263657/?dopt=Abstract Loss of mitochondrial membrane potential and caspase activation enhance apoptosis in irradiated... Two mechanisms of radiation-induced cell death in K562 cells, mitotic catastrophe and apoptosis, are regulated through distinct pathways, mitochondria and... https://www.ncbi.nlm.nih.gov/Structure/pdb/3NKF 3NKF: Crystal structure of human ligand-free mature caspase-6 with intersubunit linker attached https://scholars.duke.edu/publication/781465 Scholars@Duke publication: Apoptosis induction by caspase-8 is amplified through the mitochondrial... https://pubmed.ncbi.nlm.nih.gov/34671164/?dopt=Abstract Shigella evades pyroptosis by arginine ADP-riboxanation of caspase-11 Mouse caspase-11 and human caspase-4 and caspase-5 recognize cytosolic lipopolysaccharide (LPS) to induce pyroptosis by cleaving the pore-forming protein... shigella pyroptosis arginine adp caspase https://pubmed.ncbi.nlm.nih.gov/26174085/ Caspase-4 mediates non-canonical activation of the NLRP3 inflammasome in human myeloid cells Inflammasome activation culminates in activation of caspase-1, which leads to the maturation and subsequent release of cytokines of the interleukin 1 (IL-1)... https://pubchem.ncbi.nlm.nih.gov/bioassay/1796843 AID 1796843 - Caspase Inhibition Assay from Article 10.1016/s0968-0896(01)00250-4: "Structure-based... BioAssay record AID 1796843 submitted by BindingDB: Caspase Inhibition Assay from Article 10.1016/s0968-0896(01)00250-4: https://experts.umn.edu/en/publications/peripheral-neuropathy-in-the-twitcher-mouse-involves-the-activati-2/ Peripheral neuropathy in the Twitcher mouse involves the activation of axonal Caspase 3 -... peripheral neuropathy in the https://pubmed.ncbi.nlm.nih.gov/24350060/ Caspase-2 mediates a Brucella abortus RB51-induced hybrid cell death having features of apoptosis... Programmed cell death (PCD) can play a crucial role in tuning the immune response to microbial infection. Although PCD can occur in different forms, all are... https://www.wikidata.org/wiki/Q29620200 Regulation of an ATG7-beclin 1 program of autophagic cell death by caspase-8 - Wikidata scientific article (publication date: 4 June 2004) https://research-portal.st-andrews.ac.uk/en/publications/caspase-dependent-proteolytic-cleavage-of-stat3-alpha-in-es-cells/ Caspase-dependent proteolytic cleavage of STAT3 alpha in ES cells, in mammary glands undergoing... https://pubmed.ncbi.nlm.nih.gov/21560495/?dopt=Abstract Nitric oxide and caspase 3 mediated cytokine induced apoptosis in acute leukemia Cytokines especially interferon-y induced apoptosis in acute leukemia via NO and caspase 3 pathway. nitric oxide https://digitalcommons.usu.edu/cee_facpub/111/ "Caspase 3-dependent cell death of neurons contributes to the pathogene" by M A. Samuel, John D.... By M A. Samuel, John D. Morrey, and M S. Diamond, Published on 01/01/07 https://cordis.europa.eu/article/id/125722-skirmishing-aggressive-cancers-with-simultaneous-caspase-3-9-activation-and-cyclin-d2-b1-and- Skirmishing Aggressive Cancers with Simultaneous Caspase 3 & 9 Activation and Cyclin D2 & B1 and... A Dual Punch via elevating Benevolent Apoptosis while suppressing Malignant Proliferative Factors facilitates a Synergy that may overrule... https://researchportalplus.anu.edu.au/en/publications/dronc-an-ecdysone-inducible-drosophila-caspase/ DRONC, an ecdysone-inducible Drosophila caspase - The Australian National University the australian drosophila caspase national university https://scholars.lib.ntu.edu.tw/entities/publication/17e07f63-f34c-48db-aa8e-c793cd659d2d Effects of Hypoxia on Radiation-Responsive Stress-Activated Protein Kinase, p53, and Caspase 3... https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2023.1114620/full Frontiers | TIGAR deficiency induces caspase-1-dependent trophoblasts pyroptosis through NLRP3-ASC... Gestational diabetes mellitus (GDM), a common complication of pregnancy, is risky for both mother and fetus. Previous studies about TP53-induced glycolysis a... https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2025.1516120/full Frontiers | Caspase-11 and NLRP3 exacerbate systemic Klebsiella infection through reducing... IntroductionKlebsiella pneumoniae is a Gram-negative bacterium and the third most commonly isolated microorganism in blood cultures from septic patients. Des... frontiers caspase https://experts.umn.edu/en/publications/molecular-mechanism-of-crocin-induced-caspase-mediated-mcf-7-cell/ Molecular mechanism of crocin induced caspase mediated MCF-7 cell death: In vivo toxicity profiling... https://scholarworks.indianapolis.iu.edu/items/2c086898-e6cf-4059-a457-5a47b807b7e6 Endoplasmic Reticulum Stress Activates the Inflammasome via NLRP3- and Caspase-2-Driven... Endoplasmic reticulum (ER) stress is observed in many human diseases, often associated with inflammation. ER stress can trigger inflammation through... endoplasmic reticulum https://publications-cnrc.canada.ca/eng/view/object/?id=1fc8e438-14ab-4fe8-82d5-dadad564b6de Caspase-dependent and independant cell death in rat hepatoma 5123tc cells - NRC Publications... Caspase-dependent and independant cell death in rat hepatoma 5123tc cells https://pure.psu.edu/en/projects/non-canonical-caspase-8-activation-on-autophagosomal-membranes-4/ Non-canonical Caspase-8 Activation on Autophagosomal Membranes - Penn State non caspase activation membranes penn https://www.ncbi.nlm.nih.gov/Structure/pdb/1CWW 1CWW: SOLUTION STRUCTURE OF THE CASPASE RECRUITMENT DOMAIN (CARD) FROM APAF-1 APOPTOTIC PROTEASE ACTIVATING FACTOR 1 solution structure of the https://pubmed.ncbi.nlm.nih.gov/40257494/ Caspase-independent cell death in lung cancer: from mechanisms to clinical applications Caspase-independent cell death (CICD) has recently become a very important mechanism in lung cancer, in particular, to overcome a critical failure in apoptotic... cell death lung cancer https://su.diva-portal.org/smash/record.jsf?pid=diva2%3A547701 Increased spatiotemporal resolution of caspase activation by anchoring FRET-based sensors to... https://www.frontiersin.org/journals/oncology/articles/10.3389/fonc.2020.575854/full Frontiers | GC1qR Cleavage by Caspase-1 Drives Aerobic Glycolysis in Tumor Cells Self-sustained cell proliferation constitutes one hallmark of cancer enabled by aerobic glycolysis which is characterized by imbalanced glycolysis and mitoch... https://dukespace.lib.duke.edu/items/0669f191-3ef3-4db2-9d49-029f9e5bbd5d Caspase-1 and the inflammasome promote polycystic kidney disease progression. We and others have previously shown that the presence of renal innate immune cells can promote polycystic kidney disease (PKD) progression. In this study, we... polycystic kidney disease and the caspase promote progression https://www.mdpi.com/2073-4409/9/5/1259 The Role of Caspase-2 in Regulating Cell Fate Caspase-2 is the most evolutionarily conserved member of the mammalian caspase family and has been implicated in both apoptotic and non-apoptotic signaling... the role caspase regulating cell fate https://pubmed.ncbi.nlm.nih.gov/41477850/ Caspase-2 deficiency drives pathogenic liver polyploidy and increases age-associated hepatocellular... Hepatocyte polyploidization promotes liver homeostasis by enhancing resistance to cellular stress. Caspase-2, a proapoptotic protease, restricts... https://www.thermofisher.com/us/en/home/life-science/cell-analysis/cell-viability-and-regulation/apoptosis/caspase-assays.html Caspase Assays | Thermo Fisher Scientific - US Caspases play an important role in programmed cell death. Thermo Fisher Scientific offers reagents and kits for detecting caspase activity in real-time or as... thermo fisher scientific caspase assays us https://nrc-publications.canada.ca/eng/view/object/?id=0ff412f7-4490-48c8-a11c-ee5f991379ee Isolation and functional characterization of single domain antibody modulators of Caspase-3 and... Isolation and functional characterization of single domain antibody modulators of Caspase-3 and apoptosis single domain isolation functional characterization https://scholarworks.uvm.edu/items/b46ea670-e44f-4d17-9e72-64e2f87d329e The Contribution Of Metabolism To The Regulation Of Caspase Activity And Cell Death In T Lymphocytes During an immune response, T cell activation is mirrored by a dramatic metabolic shift from oxidative phosphorylation to glycolysis. The upregulation of... https://experts.umn.edu/en/publications/mutations-in-cradd-result-in-reduced-caspase-2-mediated-neuronal-/ Mutations in CRADD Result in Reduced Caspase-2-Mediated Neuronal Apoptosis and Cause Megalencephaly... https://scholarshare.temple.edu/entities/publication/62a6656a-37b2-45ee-9092-d202b6c9c409 THE ROLE OF CASPASE-4/11-GASDERMIN D PATHWAY IN PROMOTING VASCULAR INFLAMMATION IN CHRONIC KIDNEY... Chronic kidney disease (CKD) affects 13.4% of adults in America; and 38% in people aged 65 years or older[1]. In addition, cardiovascular disease (CVD) is the... https://www.wikidata.org/wiki/Q41050794 Caspase-dependent cleavage of signaling proteins during apoptosis. A turn-off mechanism for... scientific article published on March 1998 https://pubmed.ncbi.nlm.nih.gov/27723735/ Regulation of CED-3 caspase localization and activation by C. elegans nuclear-membrane protein... Caspases are cysteine proteases with critical roles in apoptosis. The Caenorhabditis elegans caspase CED-3 is activated by autocatalytic cleavage, a process... https://news.feinberg.northwestern.edu/2014/07/03/caspase-8_lupus/ New Role for Caspase-8 in Dendritic Cells - News Center Jul 3, 2014 - An enzyme called caspase-8 prevents the onset of autoimmune disease lupus when expressed by dendritic cells. new role dendritic cells caspase news center https://www.ncbi.nlm.nih.gov/Structure/pdb/2H65 2H65: Crystal strusture of caspase-3 with inhibitor Ac-VDVAD-Cho Ac-VDVAD-Chocaspase-3, p12 subunitcaspase-3, p17 subunit crystal caspase https://pubmed.ncbi.nlm.nih.gov/11185963/ Caspase-8 in apoptosis: the beginning of "the end"? Caspase-8 is a member of the cysteine proteases, which are implicated in apoptosis and cytokine processing. Like all caspases, caspase-8 is synthesized as an... the beginning caspase apoptosis end https://www.ncbi.nlm.nih.gov/gene?term=29775 CARD10 caspase recruitment domain family member 10 [Homo sapiens (human)] - Gene - NCBI family member https://dash.harvard.edu/entities/publication/73120378-a333-6bd4-e053-0100007fdf3b Polo-Like Kinase 1 Depletion Induces DNA Damage in Early S Prior to Caspase Activation Polo-like kinase 1 (Plk1) plays several roles in mitosis, and it has been suggested to have a role in tumorigenesis. We have previously reported that Plk1... https://www.frontiersin.org/journals/cell-and-developmental-biology/articles/10.3389/fcell.2019.00028/full Frontiers | Glycolysis Induces MCJ Expression That Links T Cell Proliferation With Caspase-3... An effective adaptive immune response requires rapid T cell proliferation, followed by equally robust cell death. These two processes are coordinately regula... https://vivo.colorado.edu/display/meshid_D08.811.277.656.262.500.126.350.300 Cysteine Proteases - Caspase 3 | CU Experts | CU Boulder cysteine proteases caspase cu experts https://pubmed.ncbi.nlm.nih.gov/18259116/ Fenretinide induces autophagic cell death in caspase-defective breast cancer cells The elimination of tumor cells by apoptosis is the main mechanism of action of chemotherapeutic drugs. More recently, autophagic cell death has been shown to... cell death breast cancer fenretinide https://repository.lib.ncsu.edu/items/9a7fca44-03dc-42bf-9483-d73f3a218966 Structure, Folding, and Assembly of (Pro)caspase-3. The Role of the Dimer Interface in Active Site... Effector procaspase-3 plays a vital role in carrying out the final steps of programmed cell death, leading to the destruction of the cell. Because dimerization... https://pubchem.ncbi.nlm.nih.gov/bioassay/624354 AID 624354 - uHTS identification of Caspase-8 TRAIL sensitizers in a luminesence assay - PubChem BioAssay record AID 624354 submitted by Sanford-Burnham Center for Chemical Genomics: uHTS identification of Caspase-8 TRAIL sensitizers in a luminesence assay. https://dash.harvard.edu/entities/publication/73120379-031c-6bd4-e053-0100007fdf3b Molecular basis of caspase-1 polymerization and its inhibition by a novel capping mechanism Inflammasomes are cytosolic caspase-1 activation complexes that sense intrinsic and extrinsic danger signals to trigger inflammatory responses and pyroptotic... https://pubmed.ncbi.nlm.nih.gov/15474362/?dopt=Abstract A novel systemically active caspase inhibitor attenuates the toxicities of MPTP, malonate, and 3NP... Molecular machinery involved in apoptosis plays a role in neuronal death in neurodegenerative disorders such as Parkinson's disease (PD) and Huntington's... https://www.pepas.org/ Synthesis and biological evaluation of Caspase Inhibitors – My WordPress Blog biological evaluation caspase inhibitors my wordpress synthesis https://www.scirp.org/journal/papercitationdetails?paperid=140090&JournalID=530 Caspase-14 Activation by Chaenomeles sinensis May Enhance Skin Barrier Function Atopic dermatitis (AD) is characterized by chronic itching and significant loss of skin barrier function. Decreased filaggrin levels have been observed in... enhance skin caspase activation chaenomeles https://scholars.duke.edu/publication/1342728 Scholars@Duke publication: Inherited human Caspase 10 mutations underlie defective lymphocyte and... https://pmc.ncbi.nlm.nih.gov/articles/PMC23461/ CLARP, a death effector domain-containing protein interacts with caspase-8 and regulates apoptosis... We have identified and characterized CLARP, a caspase-like apoptosis-regulatory protein. Sequence analysis revealed that human CLARP contains two... https://pubmed.ncbi.nlm.nih.gov/20876354/ Caspase-12 dampens the immune response to malaria independently of the inflammasome by targeting... Pathogen sensing by the inflammasome activates inflammatory caspases that mediate inflammation and cell death. Caspase-12 antagonizes the inflammasome and...