mapk - Robuta Search

https://scholars.duke.edu/publication/1618802 Scholars@Duke publication: Multispecies transcriptomics identifies SIKE as a MAPK repressor that... https://academiccommons.columbia.edu/doi/10.7916/D89C6XQG Mitogen-Activated Protein Kinase (MAPK) Pathway Regulates Branching by Remodeling Epithelial Cell... Although the growth factor (GF) signaling guiding renal branching is well characterized, the intracellular cascades mediating GF functions are poorly... protein kinase https://open.library.emory.edu/concern/publications/17e9476b-0b98-42ac-94ac-8fe4843beb80 P38 MAPK Contributes to Resistance and Invasiveness of HER2-Overexpressing Breast Cancer | OpenEmory P38 MAPK Contributes to Resistance and Invasiveness of HER2-Overexpressing Breast Cancer https://morpheus.gitlab.io/model/m0002/ SBML Import: MAPK Signaling | Morpheus Dec 12, 2020 - Introduction This model has been imported and automatically converted from SBML format by Morpheus. It shows oscillations in the MAPK signaling cascade... mapk signaling sbml import morpheus https://www.semanticscholar.org/topic/activation-of-MAPK-activity/14080 activation of MAPK activity | Semantic Scholar The initiation of the activity of the inactive enzyme MAP kinase (MAPK). [PMID:9561267] activation mapk activity semantic scholar https://docs.cloud.google.com/java/docs/reference/google-cloud-bigtable/latest/com.google.cloud.bigtable.common.Type.Map Class Type.MapK,V (2.77.0) | Java client libraries | Google Cloud Documentation https://pubchem.ncbi.nlm.nih.gov/protein/A0A8W4FES8 MAPK activated protein kinase 2 (pig) | Protein Target - PubChem Protein target information for MAPK activated protein kinase 2 (pig). Find diseases associated with this biological target and compounds tested against it in... protein kinase mapk activated pig target https://boris-portal.unibe.ch/entities/publication/1fb8ea39-c712-42e0-b7f9-0f9a17924723 HG-68COMBINED ALTERATIONS IN MAPK PATHWAY GENES, CDKN2A/B AND ATRX CHARACTERIZE ANAPLASTIC... https://drive.google.com/file/d/1XDGqWLdkRDDisWj2lRHEjKoMZnimTi0n/preview CLCA1 exacerbates lung inflammation via p38 MAPK pathway in acute respiratory distress syndrome.pdf... https://publikationen.uni-tuebingen.de/xmlui/handle/10900/104357 Evaluation of the therapeutic potential of the selective p38 MAPK inhibitor Skepinone-L and the... of the https://pmc.ncbi.nlm.nih.gov/articles/PMC7947207/ Dietary Lysine Levels Improved Antioxidant Capacity and Immunity via the TOR and p38 MAPK Signaling... An 8-week rearing trial was designed to appraise the dietary lysine levels on intestinal antioxidant capacity and immunity of grass carp fry. Six practical... https://biology.sdsu.edu/understanding-the-role-of-the-alternative-nf-kb-and-mapk-pathways-in-maintaining-quiescence-in-ovarian-cancer-stem-like-cells/ Understanding the Role of the Alternative NF-kB and MAPK Pathways in Maintaining Quiescence in... https://data.mendeley.com/datasets/5r9th34cpm/5 Phosphorylation of Hemocyanin at S293 Activates p38 MAPK Signaling to Induce Antimicrobial Peptides... This data is raw data about "Phosphorylation of Hemocyanin at S293 Activates p38 MAPK Signaling to Induce Antimicrobial Peptides in Penaeus vannamei" https://pubmed.ncbi.nlm.nih.gov/24792496/?dopt=Abstract Effects of dexmedetomidine on P2X4Rs, p38-MAPK and BDNF in spinal microglia in rats with spared... Microglia in the spinal cord is evidenced to play a crucial role in neuropathic pain. Spinal P2X4 receptors (P2X4Rs), which are mainly expressed in microglia,... https://pmc.ncbi.nlm.nih.gov/articles/PMC9733976/ Mitogen Activated Protein Kinase (MAPK) Activation, p53, and Autophagy Inhibition Characterize the... The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein and prions use common pathogenic pathways to induce toxicity in neurons.... protein kinase https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2018.00569/full Frontiers | MAPK Phosphatase-1 Deficiency Exacerbates the Severity of Imiquimod-Induced... Persistent activation of mitogen-activated protein kinase (MAPK) is believed to be involved in psoriasis pathogenesis. MAPK phosphatase-1 (MKP-1) is an impor... frontiers mapk phosphatase deficiency https://experts.arizona.edu/en/publications/loss-of-foxm1-in-macrophages-promotes-pulmonary-fibrosis-by-activ/ Loss of FOXM1 in macrophages promotes pulmonary fibrosis by activating p38 MAPK signaling pathway -... https://adisinsight.springer.com/trials/700392450?error=cookies_not_supported&code=48ba8951-b8c6-4d06-988f-f2b922727bbb Phase 1/2 Trial of Mirdametinib in Patients With MAPK Pathway Mutant Central Nervous System Tumors... The purpose of this study to find out whether mirdametinib is a safe and effective treatment for Central Nervous System/CNS tumors (glioma and https://scholars.lib.ntu.edu.tw/entities/project/f9eaae7c-f71b-4f7f-8d70-a0f777ab65c9 Exploration of Biological Significance of Mapk/Erk Signaling and Its Regulated Immune Reaction in... https://tobias-lib.uni-tuebingen.de/xmlui/handle/10900/79431?show=full Human melanoma cells resistant to MAPK inhibitors can be effectively targeted by inhibition of the... https://experts.umn.edu/en/publications/role-of-p38-mapk-in-burn-induced-intestinal-barrier-breakdownsup1/ Role of p38 MAPK in Burn-Induced Intestinal Barrier Breakdown1 - Experts@Minnesota https://pubmed.ncbi.nlm.nih.gov/24115572/ Inhibition of p38 MAPK sensitizes tumour cells to cisplatin-induced apoptosis mediated by reactive... The p38 MAPK pathway is an important regulator of many cellular responses. It is well established that p38 MAPK signalling negatively regulates epithelial cell... https://ifp.nyu.edu/2014/journal-article-abstracts/mapk-signaling-correlates-with-the-antidepressant-effects-of-ketamine/ MAPK signaling correlates with the antidepressant effects of ketamine - information for practice Aug 14, 2018 - More - MAPK signaling correlates with the antidepressant effects of ketamine mapk signaling https://pmc.ncbi.nlm.nih.gov/articles/PMC4365758/ Plumbagin induces G2/M arrest, apoptosis, and autophagy via p38 MAPK- and PI3K/Akt/mTOR-mediated... Plumbagin (5-hydroxy-2-methyl-1,4-naphthoquinone; PLB), a naturally occurring naphthoquinone isolated from the roots of Plumbaginaceae plants, has been... https://pubmed.ncbi.nlm.nih.gov/39115898/ The Impact of Hydrogen Sulfide in the Paraventricular Nucleus on the MAPK Pathway in High... The hypothalamic paraventricular nucleus (PVN) plays a central role in regulating cardiovascular activity and blood pressure. We administered hydroxylamine... the impact hydrogen sulfide https://www.thermofisher.com/proteins/target/p38%20mapk%20gamma p38 MAPK gamma Proteins | Thermo Fisher Scientific High-quality Invitrogen p38 MAPK gamma Recombinant Proteins. Species: Human. Applications: Neutralization. These proteins are expressed in Baculovirus, E. coli... thermo fisher mapk gamma proteins scientific https://pubmed.ncbi.nlm.nih.gov/23282009/?dopt=Abstract Critical role of p38 MAPK for regeneration of the sciatic nerve following crush injury in vivo This is the first study of the physiological role of p38 MAPK in nerve regeneration that does not rely on the use of pharmacological inhibitors. Our results... https://pubmed.ncbi.nlm.nih.gov/27573543/ Dehydrocorydaline promotes myogenic differentiation via p38 MAPK activation Muscle regeneration is a coordinated process that involves proliferation and differentiation of muscle progenitor cells. Activation of MyoD is a key event in... promotes differentiation via mapk activation https://repository.arizona.edu/handle/10150/657599 Elevating EGFR-MAPK program by a nonconventional Cdc42 enhances intestinal epithelial survival and... https://chera.w.uib.no/2025/06/journal-club-the-p38-pathway-inhibitor-sb202190-activates-mek-mapk-to-stimulate-the-growth-of-leukemia-cells/ Journal Club: The p38 pathway inhibitor, SB202190, activates MEK/MAPK to stimulate the growth of... https://experts.arizona.edu/en/publications/deoxycholic-acid-mediates-non-canonical-egfr-mapk-activation-thro/ Deoxycholic acid mediates non-canonical EGFR-MAPK activation through the induction of calcium... https://pubmed.ncbi.nlm.nih.gov/38549671/?dopt=Abstract CHF6297: a novel potent and selective p38 MAPK inhibitor with robust anti-inflammatory activity and... Inhibition of p38 mitogen-activated protein kinase (MAPKs) is a potential therapeutic approach for the treatment of acute and chronic pulmonary inflammatory... https://scholars.lib.ntu.edu.tw/entities/publication/322521ed-ddc6-42c3-9a5f-7bfda3c9ca3e Identification of a novel competitive inhibitor of p38alpha MAPK by a human PBMC screen of a https://portal.fis.leibniz-lsb.tum.de/en/publications/coordination-of-crosstalk-between-mapk-pkc-pathways-an-explorator-3/ Coordination of crosstalk between MAPK-PKC pathways: An exploratory study - Leibniz-LSB@TUM https://www.frontiersin.org/journals/oncology/articles/10.3389/fonc.2025.1533352/full Frontiers | Mechanisms of the JNK/p38 MAPK signaling pathway in drug resistance in ovarian cancer Ovarian cancer (OC) is the most lethal malignancy in the female reproductive system, and chemotherapy drug resistance is the main cause of treatment failure.... https://jglobal.jst.go.jp/en/detail?JGLOBAL_ID=201510031462421080 The RAS/MAPK syndromes Homepage | Research Resource Information | J-GLOBAL Research Resource "The RAS/MAPK syndromes Homepage" Detailed information of the J-GLOBAL is an information service managed by the Japan Science and Technology... research resource ras mapk syndromes homepage https://scholars.duke.edu/publication/1527400 Scholars@Duke publication: Sustained activation of JNK/p38 MAPK pathways in response to cisplatin... https://www.techtransfer.nih.gov/patent/e-066-1998-0-ep-05 Anthrax Lethal Factor is A Mapk Kinase Protease | Technology Transfer is a anthrax lethal factor mapk https://iris.cnr.it/handle/20.500.14243/459541 PARP1 negatively regulates MAPK signaling by impairing BRAF-X1 translation mapk signaling braf translation https://apice.unibo.it/xwiki/bin/view/Thesis/BoccacciMapk2012?xpage=whatsnew Modellazione e Simulazione della Cascata di Segnalazione Intracellulare MAPK su uno Spazio di Tuple... Modellazione e Simulazione della Cascata di Segnalazione Intracellulare MAPK su uno Spazio di Tuple Biochimiche https://pubmed.ncbi.nlm.nih.gov/26771170/?dopt=Abstract Isoliquiritigenin ameliorates dextran sulfate sodium-induced colitis through the inhibition of MAPK... Isoliquiritigenin (isoLQ), a chalcone found in licorice, has shown a variety of biological activity including anti-inflammatory and antioxidative effects, and... https://portal.fis.tum.de/en/publications/mapk-and-pi3kakt-mediated-yb-1-activation-promotes-melanoma-cell-/ MAPK and PI3K/AKT mediated YB-1 activation promotes melanoma cell proliferation which is... https://seguralab.duke.edu/publications/cutaneous-wound-healing-through-paradoxical-mapk-activation-by-braf-inhibitors/ Cutaneous wound healing through paradoxical MAPK activation by BRAF inhibitors | Duke University -... Apr 22, 2021 - BRAF inhibitors are highly effective therapies for the treatment of BRAF(V600)-mutated melanoma, with the main toxicity being a variety of hyperproliferative... cutaneous wound healing https://pubmed.ncbi.nlm.nih.gov/38423408/ Neuroprotective effects of Shenghui decoction via inhibition of the JNK/p38 MAPK signaling pathway... Our findings revealed the therapeutic mechanism of SHD in mitigating AD progression and suggested that SHD is a potent neuroprotectant that contributes to the... https://scholarworks.indianapolis.iu.edu/items/88d2a603-7978-445e-8bd2-0a03077b41b2 Schwannoma development is mediated by Hippo pathway dysregulation and modified by RAS/MAPK signaling Schwannomas are tumors of the Schwann cells that cause chronic pain, numbness, and potentially life-threatening impairment of vital organs. Despite the... https://profiles.wustl.edu/en/publications/involvement-of-the-p38-mapk-pathway-in-il-13-induced-mucous-cell-/ Involvement of the p38 MAPK pathway in IL-13-induced mucous cell metaplasia in mouse tracheal... https://www.nist.gov/publications/glucocorticoids-alter-bone-microvascular-barrier-mapkconnexin43-mechanisms Glucocorticoids Alter Bone Microvascular Barrier via MAPK/Connexin43 Mechanisms | NIST Jan 28, 2025 - Glucocorticoids (GCs) are standard-of-care treatments for inflammatory and immune disorders, and their long-term use increases the risk of osteoporosis. glucocorticoids alter bone microvascular barrier https://pure.psu.edu/en/projects/role-rasmapk-pathwy-in-mam-canc-promot-by-linoleic-acid-4/ ROLE RAS/MAPK PATHWY IN MAM CANC PROMOT BY LINOLEIC ACID - Penn State https://nrc-publications.canada.ca/eng/view/object/?id=65ce51f5-c741-4fec-97bc-1bda4945f32b The structure of the MAPK scaffold, MP1, bound to its partner, p14. A complex with a critical role... The structure of the MAPK scaffold, MP1, bound to its partner, p14. A complex with a critical role in endosomal map kinase signaling https://pubmed.ncbi.nlm.nih.gov/38573820/ Activating SRC/MAPK signaling via 5-HT1A receptor contributes to the effect of vilazodone on... Thrombocytopenia caused by long-term radiotherapy and chemotherapy exists in cancer treatment. Previous research demonstrates that 5-Hydroxtrayptamine (5-HT)... https://pubmed.ncbi.nlm.nih.gov/41825157/ Autophagy-centered regulation of PI3K/Akt/mTOR and MAPK signaling by traditional Chinese medicine... Gastric cancer (GC) remains a major global health burden, with high incidence and mortality rates, particularly in East Asia, driven by factors such as... https://ucrisportal.univie.ac.at/de/publications/dual-control-of-mapk-activities-by-ap2c1-and-mkp1-mapk-phosphatas/ Dual control of MAPK activities by AP2C1 and MKP1 MAPK phosphatases regulates defence responses in... https://bibliographie.uni-tuebingen.de/xmlui/handle/10900/158641 A patent review of MAPK inhibitors (2018-present) mapk inhibitors patent review present https://dukespace.lib.duke.edu/items/b2c1dc33-f888-4e38-ac7f-712c2f6d387c The role of mitogen-activated protein kinase (MAPK) in morphine tolerance and dependence. Despite the existence of a large body of information on the subject, the mechanisms of morphine tolerance and dependence are not yet fully understood. There is... https://pubmed.ncbi.nlm.nih.gov/9131167/?dopt=Abstract PAF-induced MAPK activation is inhibited by wortmannin in neutrophils and macrophages In the present study we examined the mechanism by which PAF activates MAPK in native cells such as guinea-pig neutrophils and P388D1 macrophage-like cells. We... https://dukespace.lib.duke.edu/items/2bfd44fc-d1a9-4480-8425-6558553e4eae/full Roles of MAPK Signaling Pathway in Cardiomyocyte Proliferation and Function in Engineered Cardiac... mapk signaling pathway https://pubmed.ncbi.nlm.nih.gov/33362540/?dopt=Abstract Inhibition of p38 MAPK Mitigates Lung Ischemia Reperfusion Injury by Reducing Blood-Air Barrier... https://ub01.uni-tuebingen.de/xmlui/handle/10900/158351 AGE-DEPENDENT CHANGES OF THE ANTIOXIDANT SYSTEM IN RAT LIVERS ARE ACCOMPANIED BY ALTERED MAPK... https://pmc.ncbi.nlm.nih.gov/articles/PMC38930/ The Mos/mitogen-activated protein kinase (MAPK) pathway regulates the size and degradation of the... Mos is an upstream activator of mitogen-activated protein kinase (MAPK) and, in mouse oocytes, is responsible for metaphase II arrest. This activity has been... https://bmcb.georgetown.edu/news-story/mapk-pathway-in-prostate-cancer/ Professor Djakiew publishes a book chapter entitled "The p38 MAPK Pathway in Prostate Cancer" |... Feb 5, 2014 - Professor Djakiew publishes a book chapter entitled "The p38 MAPK Pathway in Prostate Cancer" In "Prostate Cancer: Biochemistry, Molecular Biology and... https://www.wikidata.org/wiki/Q73538290 Microbial elicitors induce activation and dual phosphorylation of the Arabidopsis thaliana MAPK 6 -... scientific article published on 01 March 2000 https://pubmed.ncbi.nlm.nih.gov/16139274/ p38 MAPK is involved in CB2 receptor-induced apoptosis of human leukaemia cells Cannabinoids have been shown to inhibit the growth of a broad spectrum of tumour cells. However, the molecular mechanisms involved in that effect have not been... https://www.ncbi.nlm.nih.gov/Structure/pdb/6Q0K 6Q0K: Structure of a MAPK pathway complex 14-3-3 protein zeta/deltaSerine/threonine-protein kinase B-raf of a structure mapk pathway complex https://experts.arizona.edu/en/publications/roles-of-insulin-signalling-and-p38-mapk-in-the-activation-by-lit/ Roles of insulin signalling and p38 MAPK in the activation by lithium of glucose transport in... https://www.semanticscholar.org/topic/negative-regulation-of-MAPK-cascade/5383143 negative regulation of MAPK cascade | Semantic Scholar Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction mediated by the MAPKKK cascade. [GOC:go_curators] negative regulation mapk cascade semantic https://pubmed.ncbi.nlm.nih.gov/39951894/ Synthesis and characterization of berberine-loaded nanoliposome for targeting of MAPK pathway to... Glioblastoma (GBM), the most aggressive and lethal primary brain tumor, demands innovative therapeutic strategies to improve patient outcomes and quality of... https://pubmed.ncbi.nlm.nih.gov/21792935/?dopt=Abstract The inflammatory response of keratinocytes and its modulation by vitamin D: the role of MAPK... The hormonal form of vitamin D, calcitriol, and its analogs are known for their beneficial effect in the treatment of inflammatory skin disorders.... https://research.monash.edu/en/publications/regulation-of-erk-mapk-signaling-in-human-epidermis/ Regulation of ERK-MAPK signaling in human epidermis - Monash University mapk signaling regulation erk human epidermis https://theses.gla.ac.uk/85669/ Investigating MAPK activation thresholds in the immune decision to initiate inflammation -... in the investigating mapk activation thresholds https://profiles.wustl.edu/en/publications/various-stressors-rapidly-activate-the-p38-mapk-signaling-pathway/ Various stressors rapidly activate the p38-MAPK signaling pathway in Mytilus galloprovincialis... mapk signaling pathway https://scholars.uky.edu/en/publications/inhibition-of-ap-1-and-mapk-signaling-and-activation-of-nrf2are-p/fingerprints/?sortBy=alphabetically Inhibition of AP-1 and MAPK signaling and activation of Nrf2/ARE pathway by quercitrin -... https://pubmed.ncbi.nlm.nih.gov/37402592/ ACE2-EGFR-MAPK signaling contributes to SARS-CoV-2 infection SARS-CoV-2 triggered the most severe pandemic of recent times. To enter into a host cell, SARS-CoV-2 binds to the angiotensin-converting enzyme 2 (ACE2).... mapk signaling sars cov egfr contributes infection https://pubmed.ncbi.nlm.nih.gov/36343387/ Genotype-Tailored ERK/MAPK Pathway and HDAC Inhibition Rewires the Apoptotic Rheostat to Trigger... The EGFR/RAS/MEK/ERK signaling pathway (ERK/MAPK) is hyperactivated in most colorectal cancers. A current limitation of inhibitors of this pathway is that they... https://www.techtransfer.nih.gov/patent/e-302-2000-0-us-01 Inhibition of Mitogen-Activated Protein Kinase (MAPK) Pathway As Selective Therapeutic Strategy... protein kinase https://epub.ub.uni-muenchen.de/37435/ mTOR and MAPK: from localized translation control to epilepsy mtor mapk localized translation control https://pubmed.ncbi.nlm.nih.gov/19561096/ Role of MAPK kinase 6 in arthritis: distinct mechanism of action in inflammation and cytokine... Development of p38alpha inhibitors for rheumatoid arthritis has been hindered by toxicity and limited efficacy. Therefore, we evaluated whether MKK6, an...