https://scholars.uky.edu/es/publications/prenatal-alcohol-exposure-triggers-ceramide-induced-apoptosis-in-/
Prenatal alcohol exposure triggers ceramide-induced apoptosis in neural crest-derived tissues...
https://pmc.ncbi.nlm.nih.gov/articles/PMC8468445/
The Pathogenic and Therapeutic Implications of Ceramide Abnormalities in Atopic Dermatitis - PMC
Ceramides play an essential role in forming a permeability barrier in the skin. Atopic dermatitis (AD) is a common chronic skin disease associated with skin...
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Galactosyl ceramide or a derivative is an essential component of the neural receptor for human...
This report demonstrates that galactosyl ceramide (GalCer) or a molecule derived from it may serve as an alternative receptor for human immunodeficiency virus...
https://journals.ed.ac.uk/gtopdb-cite/article/view/3283
Ceramide turnover (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database | IUPHAR/BPS...
https://scholars.uky.edu/es/publications/genetic-architecture-of-circulating-very-long-chain-c240-and-c220/
Genetic architecture of circulating very-long-chain (C24:0 and c22:0) ceramide concentrations -
https://pmc.ncbi.nlm.nih.gov/articles/PMC4624068/
Vitamin C Stimulates Epidermal Ceramide Production by Regulating Its Metabolic Enzymes - PMC
Ceramide is the most abundant lipid in the epidermis and plays a critical role in maintaining epidermal barrier function. Overall ceramide content in...
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https://pubmed.ncbi.nlm.nih.gov/10037789/?dopt=Abstract
Genetic evidence for ATP-dependent endoplasmic reticulum-to-Golgi apparatus trafficking of ceramide...
LY-A strain is a Chinese hamster ovary cell mutant resistant to sphingomyelin (SM)-directed cytolysin and has a defect in de novo SM synthesis. Metabolic...
https://pubmed.ncbi.nlm.nih.gov/22648223/
Efficacy and safety of a ceramide containing moisturizer followed by fixed-dose clindamycin...
Combination therapy addressing multiple pathogenic factors should be used to achieve optimal outcomes in treating acne. The following study demonstrated both...
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https://scholars.uky.edu/es/publications/c6-pyridinium-ceramide-influences-alternative-pre-mrna-splicing-b/
C6 pyridinium ceramide influences alternative pre-mRNA splicing by inhibiting protein phosphatase-1...
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https://pubchem.ncbi.nlm.nih.gov/protein/H0YI10
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https://pure.psu.edu/en/publications/lysosomal-degradation-of-cd44-mediates-ceramide-nanoliposome-indu/
Lysosomal degradation of CD44 mediates ceramide nanoliposome-induced anoikis and diminished...
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https://profiles.wustl.edu/en/publications/measurement-of-ceramide-synthase-activity/fingerprints/
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https://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1011880
Individual lipid alterations at the origin of neuronal Ceramide Synthase defects | PLOS Genetics
Authors summary The brain is the most lipid-enriched organ of our body. At the same time, it is highly susceptible to disturbances in lipid metabolism. In this...
https://pubmed.ncbi.nlm.nih.gov/37653044/
A defect in mitochondrial fatty acid synthesis impairs iron metabolism and causes elevated ceramide...
In most eukaryotic cells, fatty acid synthesis (FAS) occurs in the cytoplasm and in mitochondria. However, the relative contribution of mitochondrial FAS...
https://scholars.uky.edu/es/publications/uptake-and-metabolism-of-low-density-lipoproteins-with-elevated-c/
Uptake and metabolism of low density lipoproteins with elevated ceramide content by human...
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Fas- or Ceramide-induced Apoptosis Is Mediated by a Rac1-regulated Activation of Jun N-terminal...
scientific article published on August 29, 1997
https://pittlab.weill.cornell.edu/publications/ceramide-induced-fgf13-impairs-systemic-metabolic-health
Ceramide-induced FGF13 impairs systemic metabolic health. | Pitt Lab
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https://pubmed.ncbi.nlm.nih.gov/12467215/
P-glycoprotein modulates ceramide-mediated sensitivity of human breast cancer cells to...
Alterations in metabolism of ceramide (Cer) to the noncytotoxic metabolite glucosylceramide have been implicated in the multidrug resistance (MDR) phenomenon....
https://pmc.ncbi.nlm.nih.gov/articles/PMC3774410/
Inactivation of Ceramide Synthase 6 in Mice Results in an Altered Sphingolipid Metabolism and...
Background: Ceramide synthases N-acylate (dihydro-)sphingosine to (dihydro-)ceramide in mammals. Results: Enzymatically inactive ceramide synthase 6 in mice...
https://pubmed.ncbi.nlm.nih.gov/33865303/
A cream containing linoleic acid, 5% dexpanthenol and ceramide in the treatment of atopic dermatitis
The effectiveness of LDC cream is better than 5% urea cream for improving clinical atopic dermatitis. It was suggested that moisturizer containing LDC could be...
https://pubmed.ncbi.nlm.nih.gov/33432663/
The antithetic role of ceramide and sphingosine-1-phosphate in cardiac dysfunction
Cardiovascular diseases (CVDs) are the leading cause of death globally and the number of cardiovascular patients, which is estimated to be over 30 million in...
https://experts.colorado.edu/display/pubid_142902
Starvation-Induced Stress Response Is Critically Impacted by Ceramide Levels in Caenorhabditis...
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https://www.techtransfer.nih.gov/patent/e-265-2003-0-us-03
Methods for Inhibitors of HIV and Other Viral Infection by Modulators of Ceramide Metabolism |...
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Endogenous Ceramide 24:1 Constrains Th17-Driven Neutrophilic Inflammation by Antagonizing EP2...
Dysregulated chronic inflammation underlies a spectrum of severe asthma phenotypes, among which neutrophilic asthma (NA) represents a treatment-recalcitrant...
https://www.ncbi.nlm.nih.gov/protein/8Y2N_C
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https://scholars.uky.edu/en/publications/ceramide-mediates-age-associated-increase-in-macrophage-cyclooxyg/
Ceramide mediates age-associated increase in macrophage cyclooxygenase-2 expression - University of...
https://www.semanticscholar.org/topic/ceramide-glycanase/2260067
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https://experts.arizona.edu/en/publications/expression-of-ceramide-synthases-in-mice-and-their-roles-in-regul/
Expression of Ceramide Synthases in Mice and Their Roles in Regulating Acyl-Chain Sphingolipids: A...
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https://nrc-publications.canada.ca/eng/view/object/?id=e2ab3e5d-dba9-4f28-a929-b72ec36c5870
Glycosphingolipids: 2 H-NMR study of the influence of carbohydrate headgroup structure on ceramide...
Glycosphingolipids: 2 H-NMR study of the influence of carbohydrate headgroup structure on ceramide acyl chain behavior in glycolipid phospholipid bilayers
https://pmc.ncbi.nlm.nih.gov/articles/PMC7992683/
Synthesized Ceramide Induces Growth of Dermal Papilla Cells with Potential Contribution to Hair...
The ceramide is known to play an important role in the formation of intracellular lipids, and play a crucial role as a barrier for skin and hair cuticle....
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A daily regimen of a ceramide-dominant moisturizing cream and cleanser restores the skin...
The dysfunctional skin barrier in eczema patients may be attributed to decreased levels of ceramides in the stratum corneum. The aim of this study was to...
https://pubmed.ncbi.nlm.nih.gov/34358645/
Ceramide synthase 6 mediates sex-specific metabolic response to dietary folic acid in mice
Folic acid-fortified foods and multi-vitamin supplements containing folic acid (FA) are widely used around the world, but the exact mechanisms/metabolic...
https://pubchem.ncbi.nlm.nih.gov/compound/Ceramide-PC-104
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