chk1 - Robuta Search

https://www.thermofisher.com/antibody/product/Phospho-CHK1-Ser345-Antibody-clone-PS01-17-Recombinant-Monoclonal/MA5-45974 Phospho-CHK1 (Ser345) Recombinant Rabbit Monoclonal Antibody (PS01-17) | Invitrogen (MA5-45974) Detect Phospho-CHK1 (Ser345) in WB, ICC/IF, Flow, ELISA, IHC. Reacts with Rabbit. Catalog # MA5-45974 rabbit monoclonal https://pmc.ncbi.nlm.nih.gov/articles/PMC11578078/ Combined inhibition of RAD51 and CHK1 causes synergistic toxicity in cisplatin resistant cancer... The therapeutic efficacy of the anticancer drug cisplatin is limited by acquired drug resistance. Cisplatin forms DNA crosslinks, that, if not removed, lead to... https://www.muni.cz/vyzkum/publikace/1405635 ATR-Chk1 pathway as a therapeutic target for leukemia and lymphoma | Masarykova univerzita | MUNI https://www.muni.cz/en/research/publications/1609418 ATR-CHK1 signaling is active and targetable in quiescent CLL cells | Masaryk University | MUNI https://www.ncbi.nlm.nih.gov/Structure/pdb/4QYG 4QYG: CHK1 kinase domain in complex with diazacarbazole compound 14 Serine/threonine-protein kinase Chk13-[4-(4-methylpiperazin-1-yl)phenyl]-9H-pyrrolo[2,3-b:5,4-c']dipyridine-6-carboxylic acid chk1 kinase domain complex compound https://www.rcsb.org/structure/4FTR RCSB PDB - 4FTR: Crystal Structure of the CHK1 Crystal Structure of the CHK1 rcsb pdb crystal structure of the chk1 https://www.ncbi.nlm.nih.gov/protein/7BK1_A Chain A, Serine/threonine-protein kinase Chk1 - Protein - NCBI serine threonine protein kinase chain chk1 ncbi https://www.muni.cz/en/research/publications/1388764 Synthesis and Profiling of a Novel Potent Selective Inhibitor of CHK1 Kinase Possessing Unusual... https://www.ncbi.nlm.nih.gov/Structure/pdb/3OT8 3OT8: X-ray crystal structure of compound 17r bound to human Chk1 kinase domain Serine/threonine-protein kinase Chk1GLYCEROLN-(3-methylisothiazol-5-yl)-3-(1-methyl-1H-pyrazol-4-yl)-5-[(3R)-piperidin-3-yl]pyrazolo[1,5-a]pyrimidin-7-amine x ray crystal structure https://www.rcsb.org/structure/4FTN RCSB PDB - 4FTN: Crystal Structure of the CHK1 Crystal Structure of the CHK1 rcsb pdb crystal structure of the chk1 https://www.wikidata.org/wiki/Q28507011 Aberrant cell cycle checkpoint function and early embryonic death in Chk1(-/-) mice - Wikidata scientific journal article cell cycle checkpoint https://www.rcsb.org/structure/4FTL RCSB PDB - 4FTL: Crystal Structure of the CHK1 Crystal Structure of the CHK1 rcsb pdb crystal structure of the chk1 https://www.muni.cz/en/research/publications/1405635 ATR-Chk1 pathway as a therapeutic target for leukemia and lymphoma | Masaryk University | MUNI https://www.rcsb.org/structure/4FT5 RCSB PDB - 4FT5: Crystal Structure of the CHK1 Crystal Structure of the CHK1 rcsb pdb crystal structure of the chk1 https://www.frontiersin.org/journals/oncology/articles/10.3389/fonc.2023.1271847/full Frontiers | Combined inhibition of Wee1 and Chk1 as a therapeutic strategy in multiple myeloma Multiple myeloma (MM) is a hematological malignancy characterized by an abnormal clonal proliferation of malignant plasma cells. Despite the introduction of ... https://elifesciences.org/articles/29988/figures Figures and data in Negative regulation of G2-M by ATR (mei-41)/Chk1(Grapes) facilitates... ATR/Chk1 contribute to G2 arrest in developing tracheoblasts, and arrest in G2 facilitates cellular and hypertrophic organ growth. https://elifesciences.org/articles/29988v1 Negative regulation of G2-M by ATR (mei-41)/Chk1(Grapes) facilitates tracheoblast growth and... https://www.rcsb.org/structure/2BRM RCSB PDB - 2BRM: Structure-based Design of Novel Chk1 Inhibitors: Insights into Hydrogen Bonding... Structure-based Design of Novel Chk1 Inhibitors: Insights into Hydrogen Bonding and Protein-Ligand Affinity https://elifesciences.org/articles/29988/peer-reviews Peer review in Negative regulation of G2-M by ATR (mei-41)/Chk1(Grapes) facilitates tracheoblast... ATR/Chk1 contribute to G2 arrest in developing tracheoblasts, and arrest in G2 facilitates cellular and hypertrophic organ growth. https://www.rcsb.org/structure/2E9U RCSB PDB - 2E9U: Structure of h-CHK1 complexed with A780125 Structure of h-CHK1 complexed with A780125 rcsb pdb of h structure chk1 https://www.ncbi.nlm.nih.gov/protein/3NLB_A Chain A, Serine/threonine-protein kinase Chk1 - Protein - NCBI serine threonine protein kinase chain chk1 ncbi https://pmc.ncbi.nlm.nih.gov/articles/PMC11253285/ CHK1 inhibitor SRA737 is active in PARP inhibitor resistant and CCNE1 amplified ovarian cancer - PMC High-grade serous ovarian cancers (HGSOCs) with homologous recombination deficiency (HRD) are initially responsive to poly (ADP-ribose) polymerase inhibitors... https://www.rcsb.org/structure/7SUI RCSB PDB - 7SUI: Structure of CHK1 10-pt. mutant complex with LRRK2 inhibitor 22 Structure of CHK1 10-pt. mutant complex with LRRK2 inhibitor 22