https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2024.1402514/full
Oral squamous cell carcinoma (OSCC) is a crucial public health problem, accounting for approximately 2% of all cancers globally and 90% of oral malignancies ...
as afrontierstargetingferroptosispotential
https://elifesciences.org/articles/99122v1
Upregulated by HOXA10, RUNX2 isoform II transactivates PRDX2 expression and inhibits ferroptosis and apoptosis in oral squamous cell carcinoma.
cancer cellsisoformiiprotectsferroptosis
https://www.biotechniques.com/biochemistry/ferroptosis-two-tail-fats-discovered-as-the-instigators/
Mar 22, 2024 - Two-tail fats, termed diPUFA phospholipids, demonstrated to play a crucial role in ferroptosis.
twotailfatsinvolvedferroptosis
https://pubmed.ncbi.nlm.nih.gov/38310161/
CircDCBLD2 overexpression increased PARK7 ubiquitination degradation by upregulating STUB1 through its interaction with HuR, inhibiting HSC activation and...
liver fibrosisferroptosisviafacilitating
https://pubmed.ncbi.nlm.nih.gov/36750321/
To maintain their growth rate, cancer cells must secure a supply of fatty acids, which are necessary for building cell membranes and maintaining energy...
breast cancerferroptosisacylstarvation
https://pubmed.ncbi.nlm.nih.gov/35837046/?dopt=Abstract
Pancreatic cancer (PC) is a malignant tumor with high mortality worldwide. SIRT6 plays versatile roles in human cancers. However, SIRT6 has rarely been studied...
pancreatic cancerferroptosisglycolysis
https://pubmed.ncbi.nlm.nih.gov/27668796/
The design of cancer-targeting particles with precisely tuned physicochemical properties may enhance the delivery of therapeutics and access to pharmacological...
cancer cellsnanoparticlesinduceferroptosisnutrient
https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2023.1207496/full
Hepatocellular carcinoma (HCC) is the most familiar primary hepatic malignancy with a poor prognosis. The incidence of HCC and associated deaths have risen i...
frontiersmechanismsorafenibresistanceassociated
https://www.frontiersin.org/journals/cell-and-developmental-biology/articles/10.3389/fcell.2021.790047/full
Background: Skin cutaneous melanoma (SKCM) is an aggressive malignant skin tumour. Ferroptosis is an iron-dependent cell death that may mobilize tumour-infil...
prognostic modelfrontiersnovelferroptosisrelated
https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2024.1415145/full
Sepsis-induced acute lung injury (ALI) is a major cause of death among patients with sepsis in intensive care units. By analyzing a model of sepsis-induced A...
frontiersrolemechanismsautophagyferroptosis
https://www.mdpi.com/1999-4923/15/1/118
Corneal wound, associated with pain, impaired vision, and even blindness, is the most common ocular injury. In this study, we investigated the effect of a...
novelferroptosisinhibitoruamcpotential