Robuta

https://elifesciences.org/reviewed-preprints/106716 The Structural Dynamics of IRE1 and its Interaction with Unfolded Peptides structural dynamics ire1 https://elifesciences.org/articles/30700v1 An unfolded protein-induced conformational switch activates mammalian IRE1 | eLife unfolded protein induced conformational switch https://www.ebi.ac.uk/chembl/explore/target/CHEMBL1163101 Target: Serine/threonine-protein kinase/endoribonuclease IRE1 (CHEMBL1163101) - ChEMBL Report card for Target Serine/threonine-protein kinase/endoribonuclease IRE1 (CHEMBL1163101). Homo sapiens, SINGLE PROTEIN, 2.7.11.1, 3.1.26.-, Endoplasmic... serine threonine protein kinase target endoribonuclease ire1 https://pmc.ncbi.nlm.nih.gov/articles/PMC9670206/ Unfolded protein response IRE1/XBP1 signaling is required for healthy mammalian brain aging - PMC Aging is a major risk factor to develop neurodegenerative diseases and is associated with decreased buffering capacity of the proteostasis network. We... unfolded protein response https://elifesciences.org/articles/30257/peer-reviews Peer review in In vitro FRET analysis of IRE1 and BiP association and dissociation upon endoplasmic... Quantitative FRET UPR induction assay is used to measure IRE1 and BIP association and dissociation by a variety of ER misfolded proteins and by an important...