Robuta

https://www.mdpi.com/1420-3049/27/14/4548 Conformational Properties and Putative Bioactive Targets for Novel Thiosemicarbazone Derivatives The structure assignment and conformational analysis of the thiosemicarbazones, DKI21 and DKI24, were performed through homonuclear and heteronuclear 2D... conformationalpropertiesputativebioactivetargets https://www.preprints.org/manuscript/202407.0943 Computational Methods to Predict Conformational B-cell Epitopes[v1] | Preprints.org Accurate computational prediction of B-cell epitopes can greatly enhance biomedical research and rapidly advance efforts to develop therapeutics, monoclonal... computational methodsb cellpredictconformational https://openreview.net/forum?id=ZBrSA6x9HN Learning Protocols for Non-Equilibrium Conformational Free-Energy Estimation Using Optimal... Accurate estimation of conformational free-energy differences is crucial in drug discovery, particularly for understanding protein-ligand stability and... non equilibriumfree energylearningprotocols https://elifesciences.org/articles/02674 Drastic changes in conformational dynamics of the antiterminator M2-1 regulate transcription... A combination of X-ray crystallography, molecular dynamics and small angle X-ray scattering shows that the transcription antiterminator M2-1 is a structurally... of the https://elifesciences.org/articles/45403 The dynamic conformational landscape of the protein methyltransferase SETD8 | eLife Integrated experimental-computational approaches were implemented to reveal the dynamic conformational landscape of a biologically relevant protein... dynamicconformationallandscapeproteinmethyltransferase https://elifesciences.org/articles/00691/figures Figures and data in Phosphorylation-mediated PTEN conformational closure and deactivation revealed... C-terminal phosphorylation of the lipid phosphatase PTEN drives a reduction in membrane affinity and leads to a more compact conformation that involves a C2... figuresdataphosphorylation https://www.wikidata.org/wiki/Q33709285 The conformational switch in 7-transmembrane receptors: the muscarinic receptor paradigm. - Wikidata in 7transmembrane receptorsconformationalswitch https://elifesciences.org/articles/83368v1/peer-reviews Peer review in Evolutionary divergence in the conformational landscapes of Tyrosine vs... peer reviewevolutionary divergence https://www.rcsb.org/structure/2V64 RCSB PDB - 2V64: Crystallographic structure of the conformational dimer of the Spindle Assembly... Crystallographic structure of the conformational dimer of the Spindle Assembly Checkpoint protein Mad2. rcsb pdbcrystallographic structureof the https://www.wikidata.org/wiki/Q58484512 Nuclear magnetic resonance studies on calmodulin: calcium-induced conformational change - Wikidata nuclear magnetic resonanceconformational changestudies https://www.sfu.ca/physics/news-events/events/2025/nov/Biophysics_Seminar_Keir_Neuman.html Direct observation of topoisomerase conformational dynamics - Department of Physics - Simon Fraser... directobservationtopoisomeraseconformationaldynamics https://www.rcsb.org/structure/5IH2 RCSB PDB - 5IH2: Structure, thermodynamics, and the role of conformational dynamics in the... Structure, thermodynamics, and the role of conformational dynamics in the interactions between the N-terminal SH3 domain of CrkII and proline-rich motifs in... rcsb pdb https://pmc.ncbi.nlm.nih.gov/articles/PMC22758/ Conformational changes couple Na+ and glucose transport - PMC The mechanism by which cotransport proteins couple their substrates across cell membranes is not known. A commonly proposed model is that cotransport results... conformational changescoupleglucosetransportpmc https://www.rcsb.org/structure/4NVK RCSB PDB - 4NVK: Predicting protein conformational response in prospective ligand discovery. Predicting protein conformational response in prospective ligand discovery. rcsb pdbpredictingprotein https://www.rcsb.org/structure/2YJ6 RCSB PDB - 2YJ6: Conformational changes in the catalytic domain of the CPx-ATPase CopB- B upon... Conformational changes in the catalytic domain of the CPx-ATPase CopB- B upon nucleotide binding https://pmc.ncbi.nlm.nih.gov/articles/PMC47012/ Primary structure elements responsible for the conformational switch in the envelope glycoprotein... The ability to undergo a particular conformational switch on moving from a polar to a less polar environment has been shown to be conserved at the CD4-binding... primary structurefor theelementsresponsible https://elifesciences.org/articles/78982 Conformational fingerprinting of allosteric modulators in metabotropic glutamate receptor 2 | eLife A combination of single-molecule and in vivo FRET showed how drugs affect conformation of mGluR2 at different domains. glutamate receptor 2conformationalfingerprintingallostericmodulators https://elifesciences.org/articles/37248v1 Visualizing conformational dynamics of proteins in solution and at the cell membrane | eLife https://www.frontiersin.org/research-topics/17235/conformational-diversity-of-antibodies-and-implications-for-binding-and-function/magazine Conformational Diversity of Antibodies and Implications for Binding and Function | Frontiers... In the last decades, antibodies have become one of the most important and fastest growing classes of biotherapeutic proteins. Antibodies are Y-shaped proteins... conformationaldiversityantibodiesimplicationsbinding https://elifesciences.org/reviewed-preprints/105761v1/reviews Characterization and modulation of human insulin degrading enzyme conformational dynamics to... insulin degrading enzymecharacterizationmodulationhuman https://pmc.ncbi.nlm.nih.gov/articles/PMC24463/ Key residues revealed in a major conformational epitope of the U1-70K protein - PMC Epitopes depending on three-dimensional folding of proteins have during recent years been acknowledged to be main targets for many autoantibodies. However, a... https://elifesciences.org/articles/81608 Didemnin B and ternatin-4 differentially inhibit conformational changes in eEF1A required for... Cyclic peptide natural products didemnin B and ternatin-4 bind the same hydrophobic pocket of eEF1A to inhibit mRNA translation but exhibit kinetic differences... https://snapcraft.io/confid Install ConfID: Conformational Identifier on Linux | Snap Store Get the latest version of ConfID: Conformational Identifier for Linux - Analytical method for conformational characterization using molecular dynamics installconformationalidentifierlinuxsnap https://elifesciences.org/reviewed-preprints/104901 Harnessing AlphaFold to reveal hERG channel conformational state secrets harnessingalphafoldrevealhergchannel https://edubirdie.com/docs/kentucky-state-university/che-315-biochemistry/108890-regulation-through-conformational-changes Regulation Through Conformational Changes - Edubirdie Understanding Regulation Through Conformational Changes better is easy with our detailed Lecture Note and helpful study notes. conformational changesregulationedubirdie https://elifesciences.org/reviewed-preprints/92418v2/figures Conformational dynamics of a nicotinic receptor neurotransmitter binding site nicotinic receptorconformationaldynamicsneurotransmitterbinding https://elifesciences.org/articles/92418/peer-reviews Peer review in Conformational dynamics of a nicotinic receptor neurotransmitter site | eLife MD-simulations reveal low- to high-affinity conformational shift of orthosteric site in the nicotinic acetylcholine receptor, offering insight into agonist... peer review https://www.nist.gov/publications/rotational-spectra-and-conformational-structures-of1-phenyl-2-propanol-methamphetamine Rotational Spectra and Conformational Structures of1-Phenyl-2-Propanol, Methamphetamine, and... Oct 12, 2021 - Microwave spectra have been recorded for 1-phenyl-2-propanol, methamphetamine, and 1-phenyl-2-propanone in the range 11 GHz to 24 GHz using a Fourier-transform 2 propanolrotationalspectraconformationalstructures https://elifesciences.org/articles/63201 Concerted conformational dynamics and water movements in the ghrelin G protein-coupled receptor |... A combination of state-of-the-art biochemical, biophysical, and computational methods revealed that water molecules play a central role in signal propagation... https://pmc.ncbi.nlm.nih.gov/articles/PMC43145/ Invariant tryptophan at a shielded site promotes folding of the conformational unit of spectrin -... The tryptophan that is highly conserved among repeating structural units of spectrin is reported to promote the conformational stability of one such unit of... https://elifesciences.org/reviewed-preprints/94842/reviews Differential conformational dynamics in two type-A RNA-binding domains drive the double-stranded... https://elifesciences.org/articles/20198v1 Relief of autoinhibition by conformational switch explains enzyme activation by a catalytically... enzyme activationreliefconformational https://www.growkudos.com/publications/10.1016%25252Fj.enzmictec.2016.12.003/reader Understanding the process-induced formation of minor conformational variants of Erwinia... Erwinia chrysanthemi L-asparaginase (ErA) is an enzyme, used as treatment for childhood leukaemia. When it is manufactured, certain conditions during... understanding the processinducedformationminorvariants https://elifesciences.org/reviewed-preprints/105761v2 Characterization and modulation of human insulin degrading enzyme conformational dynamics to... insulin degrading enzymecharacterizationmodulationhuman https://www.nist.gov/publications/conformational-alterations-bovine-insulin-adsorbed-silver-electrode CONFORMATIONAL ALTERATIONS OF BOVINE INSULIN ADSORBED ON A SILVER ELECTRODE | NIST on aconformationalalterationsbovineinsulin https://www.cea.fr/drf/Lists/publications20072010/StructuredDisplayForm.aspx?ID=45166 Conformational Changes Specific for Pseudophosphorylation at Serine 262 Selectively Impair Binding... conformational changesspecific https://elifesciences.org/articles/10180v1 Structure and conformational states of the bovine mitochondrial ATP synthase by cryo-EM | eLife https://elifesciences.org/articles/49806 Specific lid-base contacts in the 26s proteasome control the conformational switching required for... The 26S proteasome lid subcomplex acts as an external scaffold whose interactions with the ATPase motor stabilize the substrate-engagement-competent state, and... https://www.uni-marburg.de/de/fb16/ipc/aktuelles/events/2026/dphg_2026-04-20 Termin: From Canonical Structures to Conformational Ensembles: Physics-Based Modeling of Antibody... DPhG-Vortrag im Sommersemester 2026 conformational ensembles https://pmc.ncbi.nlm.nih.gov/articles/PMC4004233/ Non-native Soluble Oligomers of Cu/Zn Superoxide Dismutase (SOD1) Contain a Conformational Epitope... Soluble misfolded Cu/Zn superoxide dismutase (SOD1) is implicated in motor neuron death in amyotrophic lateral sclerosis (ALS); however, the relative... cu zn superoxide dismutase https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2024.1491656/full Frontiers | Quantifying conformational changes in the TCR:pMHC-I binding interface BackgroundT cells form one of the key pillars of adaptive immunity. Using their surface bound T cell antigen receptors (TCRs), these cells screen millions of... conformational changesin thefrontiers https://arxiv.org/abs/1706.08993 [1706.08993] Self-Assembled Monolayer Piezoelectrics: Electric-Field Driven Conformational Changes Abstract page for arXiv paper 1706.08993: Self-Assembled Monolayer Piezoelectrics: Electric-Field Driven Conformational Changes self assembled monolayerelectric field170608993 https://www.preprints.org/manuscript/202302.0270 The Most Stable Structure of PTB7-Th: DFT Conformational Analysis[v1] | Preprints.org PTB7-Th is an important donor copolymer used in construction of many organic devices and other industrial applications. In this work, we investigate the... https://www.mdpi.com/books/reprint/4557-the-conformational-universe-of-proteins-and-peptides-tales-of-order-and-disorder The Conformational Universe of Proteins and Peptides: Tales of Order and Disorder | MDPI Books Proteins represent one of the most abundant classes of biological macromolecules and play crucial roles in a vast array of physiological and pathological... proteins and peptides https://elifesciences.org/articles/70236v1 An improved fluorescent noncanonical amino acid for measuring conformational distributions using... Time-resolved transition metal ion fluorescence resonance energy transfer using a fluorescent, noncanonical amino acid donor and metal ion acceptor measures... amino acidimprovedfluorescentnoncanonical https://www.ncbi.nlm.nih.gov/Structure/pdb/2N9D 2N9D: Structure analysis of the Tom1 GAT domain reveals distinct ligand-specific conformational... Target of Myb protein 1 https://www.ncbi.nlm.nih.gov/Structure/pdb/1DI4 1DI4: ROLE OF AMINO ACID RESIDUES AT TURNS IN THE CONFORMATIONAL STABILITY AND FOLDING OF HUMAN... LYSOZYME CSODIUM ION https://pmc.ncbi.nlm.nih.gov/articles/PMC4367447/ Monitoring protein conformational changes and dynamics using stable-isotope labeling and mass... Understanding the mechanism accompanying functional conformational changes associated with protein activation has important implications for drug design. Here,... conformational changesstable isotopemonitoringprotein https://elifesciences.org/articles/66194v1 Conformational dynamics of auto-inhibition in the ER calcium sensor STIM1 | eLife auto inhibition https://www.mdpi.com/1420-3049/27/23/8567 An Efficient Approach to Large-Scale Ab Initio Conformational Energy Profiles of Small Molecules Accurate conformational energetics of molecules are of great significance to understand maby chemical properties. They are also fundamental for high-quality... https://www.ncbi.nlm.nih.gov/Structure/pdb/2I3V 2I3V: Measurement of conformational changes accompanying desensitization in an ionotropic glutamate... Glutamate receptor 2GLUTAMIC ACIDZINC ION conformational changesmeasurement https://elifesciences.org/articles/57180 Controlling protein function by fine-tuning conformational flexibility | eLife Specific and non-specific conformational confinement, via point mutation or cochaperone interaction or macro-molecular crowding, stimulates protein function in... protein functionfine tuningcontrollingconformationalflexibility https://www.rcsb.org/structure/5TAK RCSB PDB - 5TAK: Conformational Sampling Differences across the Arrhenius Plot Biphasic Break Point... Conformational Sampling Differences across the Arrhenius Plot Biphasic Break Point at Ambient Temperature in the Enzyme Thermolysin https://elifesciences.org/reviewed-preprints/89489v2/figures Conformational heterogeneity of the BTK PHTH domain drives multiple regulatory states of theconformationalheterogeneitybtk https://www.rcsb.org/structure/8RKU RCSB PDB - 8RKU: Conformational Landscape of the Type V-K CRISPR-associated TransposonIntegration... Conformational Landscape of the Type V-K CRISPR-associated TransposonIntegration Assembly CAST V-K TnsC domain local-refinement map https://elifesciences.org/articles/81150/peer-reviews Peer review in Structure of Dunaliella photosystem II reveals conformational flexibility of stacked... Photosystem II, the pigment-protein complex responsible for water oxidation in photosynthesis, was found to exist in two different core conformations with... peer review https://www.nist.gov/publications/label-free-detection-conformational-changes-switchable-dna-nanostructures-microwave Label-Free Detection of Conformational Changes in Switchable DNA Nanostructures with Microwave... Jan 27, 2020 - Detection of conformational changes in biomolecular assemblies provides critical information into biological and self-assembly processes. label freeconformational changes https://elifesciences.org/articles/11189v1 Revealing an outward-facing open conformational state in a CLC Cl-/H+ exchange transporter | eLife https://pmc.ncbi.nlm.nih.gov/articles/PMC21533/ Microsecond atomic force sensing of protein conformational dynamics: Implications for the primary... In this paper a new atomic force sensing technique is presented for dynamically probing conformational changes in proteins. The method is applied to the... force sensing https://elifesciences.org/articles/57003 Periprotein lipidomes of Saccharomyces cerevisiae provide a flexible environment for conformational... Analysis of periprotein lipids by direct extraction of membrane proteins, using styrene-maleic acid polymers. saccharomyces cerevisiae https://pmc.ncbi.nlm.nih.gov/articles/PMC22632/ Adjustment of conformational flexibility is a key event in the thermal adaptation of proteins - PMC 3-Isopropylmalate dehydrogenase (IPMDH, E.C. 1.1.1.85) from the thermophilic bacterium Thermus thermophilus HB8 is homologous to IPMDH from the mesophilic... https://www.ncbi.nlm.nih.gov/Structure/pdb/1XY1 1XY1: CRYSTAL STRUCTURE ANALYSIS OF DEAMINO-OXYTOCIN. CONFORMATIONAL FLEXIBILITY AND RECEPTOR... BETA-MERCAPTOPROPIONATE-OXYTOCIN crystal structuredeamino oxytocinanalysis https://pmc.ncbi.nlm.nih.gov/articles/PMC10457384/ Visualizing single-molecule conformational transition and binding dynamics of intrinsically... Intrinsically disordered proteins (IDPs) play crucial roles in cellular processes and hold promise as drug targets. However, the dynamic nature of IDPs remains... single moleculeconformational transitionvisualizingbindingdynamics https://www.rti.org/publication/pervasive-conformational-fluctuations-microsecond-time-scales-fibronectin-type-iii-domain Pervasive conformational fluctuations on microsecond time scales in a fibronectin type III domain |... A novel off-resonance rotating-frame N-15 NMR spin relaxation experiment is used to characterize conformational fluctuations with correlation times between 32... https://elifesciences.org/articles/04389 Sequential conformational rearrangements in flavivirus membrane fusion | eLife The West Nile Virus envelope protein catalyzes membrane fusion through low-pH induced conformational rearrangement, with a rate determined by the formation of... membrane fusionsequentialconformationalrearrangementsflavivirus https://www.growkudos.com/publications/10.1111%252Fmmi.14646/reader Evidence for dynamic in vivo interconversion of the conformational states of IscU during... Assembly of Fe-S clusters is assisted by complex machinery involving an Fe-S scaffold (IscU) and a dedicated chaperone system (HscBA). Here, we identify and... in vivo https://pmc.ncbi.nlm.nih.gov/articles/PMC5538678/ Conformational risk factors of brachycephalic obstructive airway syndrome (BOAS) in pugs, French... Extremely brachycephalic, or short-muzzled, dog breeds such as pugs, French bulldogs, and bulldogs are prone to the conformation-related respiratory... risk factors https://pmc.ncbi.nlm.nih.gov/articles/PMC15321/ Single-molecule fluorescence spectroscopy of enzyme conformational dynamics and cleavage mechanism... Fluorescence resonance energy transfer and fluorescence polarization anisotropy are used to investigate single molecules of the enzyme staphylococcal nuclease.... single moleculefluorescence spectroscopy https://elifesciences.org/articles/20198/peer-reviews Peer review in Relief of autoinhibition by conformational switch explains enzyme activation by a... A catalytically dead paralog activates its cognate enzyme through an allosteric mechanism that combined structural and phylogenomic analysis indicates arose... https://elifesciences.org/reviewed-preprints/94842v2/reviews Differential conformational dynamics in two type-A RNA-binding domains drive the double-stranded... https://elifesciences.org/articles/30700v1 An unfolded protein-induced conformational switch activates mammalian IRE1 | eLife unfoldedproteininducedconformationalswitch https://www.wikidata.org/wiki/Q40492842 Conformational transitions of poly(dA-dC).poly(dG-dT) induced by high salt or in ethanolic solution... https://elifesciences.org/articles/27369/figures Figures and data in Mechanism of environmentally driven conformational changes that modulate H-NS... The DNA-bridging efficiency of H-NS, a genome organising and transcription regulatory protein, is modulated by changes in environmental conditions of the cell,... https://elifesciences.org/articles/13876 VEGFR-2 conformational switch in response to ligand binding | eLife A receptor for vascular endothelial growth factor forms dimers in the absence of its ligand, and ligand-binding leads to structural changes that result in... vegfr 2in responseligand bindingconformationalswitch https://www.osti.gov/pages/biblio/2471040-conformational-heterogeneity-btk-phth-domain-drives-multiple-regulatory-states Conformational heterogeneity of the BTK PHTH domain drives multiple regulatory states (Journal... The U.S. Department of Energy's Office of Scientific and Technical Information of the https://elifesciences.org/reviewed-preprints/102002 A conformational fingerprint for amyloidogenic light chains conformationalfingerprintamyloidogeniclightchains https://www.cea.fr/drf/english/Lists/publications20112013/StructuredDisplayForm.aspx?ID=11050 Sampling the Conformational Energy Landscape of a Hyperthermophilic Protein by Engineering Key... energy landscape https://arxiv.org/abs/0908.0323 [0908.0323] Maximum Flux Transition Paths of Conformational Change Abstract page for arXiv paper 0908.0323: Maximum Flux Transition Paths of Conformational Change 09080323maximumfluxtransition https://pmc.ncbi.nlm.nih.gov/articles/PMC19090/ Monitoring conformational dynamics of a single molecule by selective fluorescence spectroscopy - PMC A recently developed, real-time spectroscopic technique, burst-integrated fluorescence lifetime (BIFL), is shown to be well suited for monitoring the... a single https://elifesciences.org/reviewed-preprints/89489/reviews Conformational heterogeneity of the BTK PHTH domain drives multiple regulatory states of theconformationalheterogeneitybtk https://www.wikidata.org/wiki/Q72697997 Antigenic markers of V domain of mouse MOPC 21 IgG1 L chain. The conformational basis of VL domain... scientific article published on 01 May 1983 https://elifesciences.org/articles/82584 Timeline of changes in spike conformational dynamics in emergent SARS-CoV-2 variants reveal... Structural mass spectrometry reveals conformational changes in emerging SARS-CoV-2 spike protein variants that correlate with increased viral fitness. sars cov 2 variants https://elifesciences.org/reviewed-preprints/95304/figures Dissecting Mechanisms of Ligand Binding and Conformational Changes in the Glutamine-Binding Protein ligand binding https://www.nist.gov/publications/rotational-spectra-conformational-structures-and-dipole-moments-thiodiglycol-jet-0 Rotational Spectra, Conformational Structures and Dipole Moments of Thiodiglycol by Jet-Cooled FTMW... Oct 12, 2021 - The rotational spectra of three low-energy conformers of thiodiglycol (TDG) (HOCH2CH2SCH2CH2OH) have been measured in a molecular beam using a pulsed-nozzle Fou https://elifesciences.org/articles/73384 Conformational decoupling in acid-sensing ion channels uncovers mechanism and stoichiometry of... A peptide toxin with therapeutic potential in stroke and pain induces multiple long-lasting conformational changes in acid-sensing ion channels and affects how... acid sensing ion channels https://www.ncbi.nlm.nih.gov/nuccore/1ZE2_C Chain C, Conformational change of pseudouridine 55 synthase upon its a - Nucleotide - NCBI https://www.preprints.org/manuscript/201608.0198 Conformational Flexibility and the Interaction of Huperzine A in the Active Site of... Huperzine A is an herbal reversible inhibitor of Acetylcholinesterase (AChE). A molecular docking analysis on Huperzine A molecule has been carried out to... huperzine aconformationalflexibilityinteraction https://elifesciences.org/reviewed-preprints/105138 Conformational changes, excess area, and elasticity of the Piezo protein-membrane nanodome from... https://pmc.ncbi.nlm.nih.gov/articles/PMC10810195/ Interaction of histone H4 with Cse4 facilitates conformational changes in Cse4 for its sumoylation... Mislocalization of overexpressed CENP-A (Cse4 in budding yeast, Cnp1 in fission yeast, CID in flies) contributes to chromosomal instability (CIN) in yeasts,... https://elifesciences.org/articles/81150v1 Structure of Dunaliella Photosystem II reveals conformational flexibility of stacked and unstacked... photosystem iistructuredunaliella https://elifesciences.org/articles/65498/figures Figures and data in Allosteric conformational ensembles have unlimited capacity for integrating... The effective higher-order binding cooperativities arising from an ensemble of dynamically interchanging conformations are identified and shown to fully... conformational ensembles https://elifesciences.org/reviewed-preprints/102288 Conformational dynamics and asymmetry in multimodal inhibition of membrane-bound pyrophosphatases membrane boundconformationaldynamicsasymmetry https://www.mdpi.com/1999-4915/13/8/1655 Identification of a Common Conformational Epitope on the Glycoprotein E2 of Classical Swine Fever... Classical swine fever virus (CSFV) shares high structural and antigenic homology with bovine viral diarrhea virus (BVDV) and border disease virus (BDV).... https://www.nist.gov/publications/structural-and-dynamical-order-disordered-protein-molecular-insights-conformational Structural and Dynamical Order of a Disordered Protein: Molecular Insights into Conformational... Oct 12, 2021 - Folded proteins show a high degree of structural order and undergo (fairly constrained) collective motions related to their functions. order of https://pmc.ncbi.nlm.nih.gov/articles/PMC17735/ Ligand-induced conformational changes observed in single RNA molecules - PMC We present the first demonstration that fluorescence resonance energy transfer can be used to track the motion of a single molecule undergoing conformational... conformational changesligandinducedobservedsingle https://www.wikidata.org/wiki/Q53001853 Conformational changes in proteins as measured by difference sedimentation studies. II. Effect of... scientific article published on May 11, 1971 https://www.nist.gov/publications/conformational-changes-associated-receptor-stimulated-guanine-nucleotide-exchange Conformational Changes Associated With Receptor-Stimulated Guanine Nucleotide Exchange in a... Feb 19, 2017 - Solution NMR studies of a 15N-labeled G-protein ?-subunit (G?) chimera (15N-ChiT) reconstituted heterotrimer have previously shown that binding of ??-subunits i conformational changesassociated withreceptor https://www.rcsb.org/structure/1ZE2 RCSB PDB - 1ZE2: Conformational change of pseudouridine 55 synthase upon its association with RNA... Conformational change of pseudouridine 55 synthase upon its association with RNA substrate https://www.kth.se/forskning/kalender/deciphering-conformational-ensembles-and-communication-pathways-in-biomolecules-1.1031622?date=2020-12-18&orgdate=2020-01-18&length=1&orglength=349 Deciphering conformational ensembles and communication pathways in biomolecules | KTH conformational ensemblesdecipheringcommunicationpathwaysbiomolecules https://elifesciences.org/articles/83868/peer-reviews Peer review in Conformational regulation and target-myristoyl switch of calcineurin B homologous... The target-myristoyl switch induced by protein-protein interaction is a novel regulatory mechanism for myristoylated EF-hand calcium-binding proteins, in which...