https://pubmed.ncbi.nlm.nih.gov/35978311/
Neuroinflammation is instigated by the misfiring of immune cells in the central nervous system (CNS) involving microglia and astrocytes as key cell-types....
microglial cellsastrocyticneuroinflammation
https://www.mayo.edu/research/labs/molecular-neurotherapeutics/focus-areas/altered-microglial-function-augmented-neuritogenic-factor-maternal-immune-activation
Mayo Clinic's Molecular Neurotherapeutics Lab demonstrated that maternal immune insults perturb microglial phenotypes and influence neuronal functions...
alteredmicroglialfunctionaugmentedfactor
https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2021.635762/full
Depression is a severe neurological disorder highly associated with chronic mental stress stimulation, which involves chronic inflammation and microglial act...
chronic stressdepressive symptomsfrontierssalidrosideimproves
https://pubmed.ncbi.nlm.nih.gov/36151874/
The mammalian gut contains a large, complex community of microorganisms collectively termed the microbiota. It is increasingly appreciated that gut microbes...
regulationmicroglialphysiologymicrobiota
https://www.prnewswire.com/news-releases/aperture-therapeutics-announces-development-candidate-targeting-cd33-to-restore-microglial-homeostasis-in-ftd-and-als-302620390.html?tc=eml_cleartime
/PRNewswire/ -- Aperture Therapeutics, a biotechnology company pioneering next-generation precision medicines for neurodegenerative diseases, today announced...
aperturetherapeuticsannouncesdevelopmentcandidate
https://elifesciences.org/articles/62167/figures
In vivo time lapse imaging reveals that microglial trogocytosis of presynaptic elements is regulated by the complement system which controls axon morphogenesis...
complement systemfiguresdatamicroglialtrogocytosis
https://www.frontiersin.org/journals/cellular-neuroscience/articles/10.3389/fncel.2024.1374298/full
Microglia play a critical role in maintaining brain homeostasis but become dysregulated in neurodegenerative diseases. Regulator of G-protein Signaling 10 (R...
frontiersmitigateshighglucoseinduced