Robuta

https://scholars.duke.edu/publication/709585 Scholars@Duke publication: Production of superoxide anions by a CNS macrophage, the microglia. https://ophthalmology.wustl.edu/retinal-microglia-links-to-circadian-rhythms/ First-of-Its-Kind Apte Lab Study Links Retinal Microglia to Circadian Rhythms Feb 19, 2026 - Apte Lab publishes a new study in Glia revealing the circadian rhythm of retinal microglia and implications for eye and CNS health. first of its kind https://pmc.ncbi.nlm.nih.gov/articles/PMC8662994/ Fluoxetine Potentiates Phagocytosis and Autophagy in Microglia - PMC Fluoxetine is a classic antidepressant drug, and its immunomodulatory effects have recently been reported in many disease models. In addition, it has strong... fluoxetinephagocytosisautophagymicrogliapmc https://pmc.ncbi.nlm.nih.gov/articles/PMC4288529/ Microglia in the tumor microenvironment: taking their TOLL on glioma biology - PMC in thetumor microenvironment https://scholars.uky.edu/es/publications/neuron-microglia-dialogue-and-hippocampal-neurogenesis-in-the-age/ Neuron-microglia dialogue and hippocampal neurogenesis in the aged brain - in theneuronmicrogliadialogueneurogenesis https://pubmed.ncbi.nlm.nih.gov/24995975/?dopt=Abstract Sublime microglia: expanding roles for the guardians of the CNS Recent findings challenge the concept that microglia solely function in disease states in the central nervous system (CNS). Rather than simply reacting to CNS... for thesublimemicrogliaexpandingroles https://pmc.ncbi.nlm.nih.gov/articles/PMC5963417/ Roles of microglia in brain development, tissue maintenance and repair - PMC The number of functions ascribed to microglia has increased greatly in recent years. Michell-Robinson et al. review the roles of microglia in health and... maintenance and repairbrain developmentrolesmicroglia https://wp0.vanderbilt.edu/youngscientistjournal/tag/microglia microglia | Young Scientist Journal | Vanderbilt University young scientistmicrogliajournalvanderbiltuniversity https://pubs.rsc.org/en/content/articlelanding/2023/fo/d3fo00122a Ketogenic diet attenuates neuroinflammation and induces conversion of M1 microglia to M2 in an EAE... Multiple sclerosis (MS) is an autoimmune disorder characterized by demyelination and neurodegeneration in the central nervous system (CNS); severe symptoms... https://pharmacology.arizona.edu/regulation-blood-brain-barrier-integrity-microglia-health-and-disease-therapeutic-opportunity Regulation of blood-brain barrier integrity by microglia in health and disease: A therapeutic... https://pubmed.ncbi.nlm.nih.gov/24792496/?dopt=Abstract Effects of dexmedetomidine on P2X4Rs, p38-MAPK and BDNF in spinal microglia in rats with spared... Microglia in the spinal cord is evidenced to play a crucial role in neuropathic pain. Spinal P2X4 receptors (P2X4Rs), which are mainly expressed in microglia,... https://seguralab.duke.edu/publications/particle-hydrogels-decrease-cerebral-atrophy-and-attenuate-astrocyte-and-microglia-macrophage-reactivity-after-stroke/ Particle Hydrogels Decrease Cerebral Atrophy and Attenuate Astrocyte and Microglia/Macrophage... Jul 16, 2022 - Increasing numbers of individuals live with stroke related disabilities. Following stroke, highly reactive astrocytes and pro-inflammatory microglia can... cerebral atrophyparticlehydrogelsdecreaseattenuate https://pubmed.ncbi.nlm.nih.gov/37952151/?dopt=Abstract Jedi-1/MEGF12-mediated phagocytosis controls the pro-neurogenic properties of microglia in the... Microglia are the primary phagocytes in the central nervous system and clear dead cells generated during development or disease. The phagocytic process shapes... https://www.news-medical.net/webinar/Understanding-neuroinflammation-Exploring-the-potential-of-iPSC-derived-microglia-for-disease-Modeling-and-drug-discovery Understanding neuroinflammation: Exploring the potential of iPSC-derived microglia for disease... This webinar explores the key role of microglia in neuroinflammation research. Featuring expert Dr. Tilman, she discusses the functional capabilities of... exploring theunderstandingneuroinflammationpotential https://vtechworks.lib.vt.edu/items/674de5a9-d3b7-44e3-b5a4-947f26c72666 Systems-Level Proteomics Evaluation of Microglia Response to Tumor-Supportive Anti-Inflammatory... Background Microglia safeguard the CNS against injuries and pathogens, and in the presence of certain harmful stimuli are capable of inducing a... https://pmc.ncbi.nlm.nih.gov/articles/PMC13115098/ Astro-Versus Microglia-Enriched Transcriptomes from Aged Atxn2-CAG100-Knockin Mice Suggest... Spinocerebellar Ataxia type 2 (SCA2) and Amyotrophic Lateral Sclerosis type 13 (ALS13) are triggered by polyglutamine expansion in Ataxin-2 (ATXN2). To... https://pubmed.ncbi.nlm.nih.gov/40333183/ The NLRP3 inflammasome in microglia regulates repetitive behavior by modulating NMDA glutamate... Neuroinflammation is a well-established risk factor for various neurological disorders and cognitive decline. However, the precise molecular mechanisms linking... https://www.frontiersin.org/research-topics/25406/modulation-of-microglia-reactivity-and-plasticity-in-cns-injury/magazine Modulation of Microglia Reactivity and Plasticity in CNS Injury | Frontiers Research Topic Microglia are considered among the most versatile cells in the brain and involved in series of central nervous system (CNS) diseases. Meanwhile, microglia are... https://medicine.yale.edu/trial/pet-imaging-of-microglia-with-11cpbr28-in-opioid-dependent-and-healthy-control-subjects/ PET Imaging of Microglia with [11C]PBR28 in Opioid Dependent and Healthy Control Subjects | Yale... This study aims to examine inflammation processes in the brain (neuroinflammatory and microglia markers). The proposed study will fill a major gap in our https://pubmed.ncbi.nlm.nih.gov/35481836/ Neuronal apoptosis drives remodeling states of microglia and shifts in survival pathway dependence Microglia serve critical remodeling roles that shape the developing nervous system, responding to the changing neural environment with phagocytosis or soluble... https://pmc.ncbi.nlm.nih.gov/articles/PMC8079643/ SARS-CoV-2 Spike Targets USP33-IRF9 Axis via Exosomal miR-148a to Activate Human Microglia - PMC SARS-CoV-2, the novel coronavirus infection has consistently shown an association with neurological anomalies in patients, in addition to its usual respiratory... https://www.frontiersin.org/journals/neuroscience/articles/10.3389/fnins.2023.1125428/full Frontiers | Microglia and astrocytes underlie neuroinflammation and synaptic susceptibility in... Autism spectrum disorder (ASD) is a common neurodevelopmental disorder with onset in childhood. The mechanisms underlying ASD are unclear. In recent years, t... frontiersmicrogliaastrocytesneuroinflammationsynaptic https://pmc.ncbi.nlm.nih.gov/articles/PMC5656389/ Gamma frequency entrainment attenuates amyloid load and modifies microglia - PMC Changes in gamma oscillations (20-50 Hz) have been observed in several neurological disorders. However, the relationship between gamma and cellular pathologies... gammafrequencyentrainmentamyloidload https://data.mendeley.com/datasets/2gtcvmf4t2/1 Endothelin-1 as an Activator of Pro-inflammatory Microglia Cells in Multiple Sclerosis - Mendeley... Background: Multiple sclerosis (MS) is a neurodegenerative autoimmune disease characterized by inflammation, demyelination, and axonal degeneration. In MS... https://cordis.europa.eu/project/id/892572/results/pl Molecular Imaging of Microglia | MIM | Projekt | Wyniki | H2020 | CORDIS | Komisja Europejska Deliverables, publications, datasets, software, exploitable results molecular imagingmicrogliamim https://fse.studenttheses.ub.rug.nl/27570/ The effect of microglia repopulation followed by secondary de-/remyelination on microglia... the effectfollowed bymicroglia https://kclpure.kcl.ac.uk/portal/en/publications/microglia-toxicity-in-preterm-brain-injury/ Microglia toxicity in preterm brain injury - King's College London brain injurymicrogliatoxicitypretermking https://www.mendeley.com/catalogue/70c14d8c-c35f-3d70-967a-b6fc580f96aa/ Gas6 Promotes Microglia Efferocyt... preview & related info | Mendeley (2023) Tang et al. Translational Stroke Research. Early brain injury (EBI) following subarachnoid hemorrhage (SAH) is characterized by rapid development of... related infopromotesmicrogliapreviewmendeley https://researchconnect.buffalo.edu/en/publications/pet-imaging-of-microglia-by-targeting-macrophage-colony-stimulati/ PET imaging of microglia by targeting macrophage colony-stimulating factor 1 receptor (CSF1R) -... https://researchconnect.buffalo.edu/en/publications/coherent-raman-spectroscopic-imaging-to-characterize-microglia-ac/ Coherent Raman spectroscopic imaging to characterize microglia activation pathway - SUNY University... coherentramanimaging https://www.research.va.gov/about/funded_research/proj-details-FY2023.cfm?pid=706843 I01BX005348-01A1 - Microglia-Vascular Interaction in Alteration of Blood-Retinal Barrier in... microgliavascularinteraction https://www.frontiersin.org/journals/cellular-neuroscience/articles/10.3389/fncel.2021.768059/full Frontiers | Neutralization of Hv1/HVCN1 With Antibody Enhances Microglia/Macrophages Myelin... Microglia dynamically monitor the microenvironment of the CNS by constantly extending and retracting their processes in physiological condition, and microgli... frontiersneutralization https://brainandmind.weill.cornell.edu/early-life-high-fructose-exposure-disrupts-microglia-function-and-impedes-neurodevelopment Early life high fructose exposure disrupts microglia function and impedes neurodevelopment. | Feil... early life https://pubmed.ncbi.nlm.nih.gov/?term=resident%20microglia resident microglia - Search Results - PubMed resident microglia - Search Results - PubMed search resultsresidentmicrogliapubmed https://www.sfb-trr167.uni-freiburg.de/publications/a-binary-cre-transgenic-approach-dissects-microglia-and-cns-border-associated-macrophages/ A Binary Cre Transgenic Approach Dissects Microglia and CNS Border-Associated Macrophages : SFB/TRR... https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2018.03150/full Frontiers | Dietary Iron Deficiency Impaired Peripheral Immunity but Did Not Alter Brain Microglia... During the postnatal period the developing brain is vulnerable to insults including nutrient insufficiency and infection that may lead to disrupted developme... https://pubmed.ncbi.nlm.nih.gov/35878284/ The Antiepileptic Drug and Toxic Teratogen Valproic Acid Alters Microglia in an Environmental Mouse... Autism spectrum disorder (ASD), a neurodevelopmental condition affecting approximately 1 in 44 children in North America, is thought to be a connectivity... https://www.repository.cam.ac.uk/items/8b85c37e-40fc-45e1-b292-fd05a8b97f33 Neurotoxic reactive astrocytes are induced by activated microglia Reactive astrocytes are strongly induced by central nervous system (CNS) injury and disease, but their role is poorly understood. Here we show that a subtype... reactiveastrocytesinducedactivatedmicroglia https://experts.umn.edu/en/publications/cryptococcal-glucuronoxylomannan-induces-interleukin-il-8-product/ Cryptococcal glucuronoxylomannan induces interleukin (IL)-8 production by human microglia but... interleukinil https://fujifilmbiosciences.fujifilm.com/standard-protocol-for-immunohistochemistry-of-microglia-using-lba1-antibody Standard Protocol for Immunohistochemistry of Microglia using Iba1 antibody FUJIFILM Biosciences is a global life sciences and medical media provider with an array of innovative products to assist your advances in healthcare. standard protocolimmunohistochemistrymicrogliausingantibody https://www.frontiersin.org/research-topics/40057/insights-on-neuroinflammatory-response-by-microglia-targeted-pharmacology/magazine Insights on Neuroinflammatory Response by Microglia-Targeted Pharmacology | Frontiers Research Topic Microglia, the innate immune cells of the CNS, are critical for the regulation of the neuronal network, from early neuronal developmental stages to adulthood.... insightsneuroinflammatoryresponse https://conservancy.umn.edu/items/b8fe26e1-6805-4800-b3c9-ad00c079dcfc Exosomes secreted by microglia contribute to virus persistence and demyelinating disease Multiple sclerosis (MS) is a chronic autoimmune-mediated demyelinating disease that affects more than 2.3 million people worldwide, especially young adults.... exosomessecretedmicrogliacontribute https://www.frontiersin.org/journals/cellular-neuroscience/articles/10.3389/fncel.2022.984690/full Frontiers | The multiple faces of extracellular vesicles released by microglia: Where are we 10... As resident component of the innate immunity in the central nervous system (CNS), microglia are key players in pathology. However, they also exert fundamenta... https://brainandmind.weill.cornell.edu/dap12-deficiency-alters-microglia-oligodendrocyte-communication-and-enhances-resilience-against-tau DAP12 deficiency alters microglia-oligodendrocyte communication and enhances resilience against tau... deficiencyaltersmicroglia https://scholars.uky.edu/en/publications/role-of-microglia-in-postinjury-repair-and-regeneration-of-the-cn/ Role of microglia in postinjury repair and regeneration of the CNS - University of Kentucky https://experts.arizona.edu/en/publications/rod-microglia-a-morphological-definition/ Rod microglia: A morphological definition - University of Arizona university ofrodmicrogliadefinitionarizona https://pubmed.ncbi.nlm.nih.gov/33221486/?dopt=Abstract Chemogenetic manipulation of microglia inhibits neuroinflammation and neuropathic pain in mice Microglia play an important role in the central sensitization and chronic pain. However, a direct connection between microglial function and pain development... neuropathic painmanipulationmicroglia https://www.igf.cnrs.fr/en/each-microglia-has-its-own-job-2/ IGF - Each microglia has its own job! Nov 6, 2024 - Microglial cells are the innate immune cells of the central nervous system. Learn more... its ownigfmicrogliajob https://eprints.ncl.ac.uk/289165 Incorporating microglia-like cells in human induced pluripotent stem cell-derived retinal organoids... https://www.thermofisher.com/us/en/home/references/protocols/cell-culture/stem-cell-protocols/ipsc-protocols/microglia-differentiation-protocols.html Microglia Differentiation Protocols | Thermo Fisher Scientific - US Explore research on microglial differentiation. Access methodologies, workflows, and easily add essential reagents to your cart for replicating experiments. thermo fisher scientificmicrogliadifferentiationprotocolsus https://pubmed.ncbi.nlm.nih.gov/25523105/?dopt=Abstract&holding=idemdclib_fft&otool=idemdclib The subpopulation of microglia expressing functional muscarinic acetylcholine receptors expands in... Microglia undergo a process of activation in pathology which is controlled by many factors including neurotransmitters. We found that a subpopulation (11 %) of... microgliaexpressing https://pubmed.ncbi.nlm.nih.gov/40205047/ Immune checkpoint TIM-3 regulates microglia and Alzheimer's disease immune checkpointtimmicrogliaalzheimerdisease https://pubmed.ncbi.nlm.nih.gov/35579329/ A unique cerebellar pattern of microglia activation in a mouse model of encephalopathy of... Preterm infants often show pathologies of the cerebellum, which are associated with impaired motor performance, lower IQ and poor language skills at school... a uniquemouse modelpattern https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2020.546415/full Frontiers | Memory-Like Responses of Brain Microglia Are Controlled by Developmental State and... Microglia, the innate immune cells of the central nervous system feature adaptive immune memory with implications for brain homeostasis and pathologies. Howe... https://www.neuromod.uni-freiburg.de/research/publications/flow-cytometry-based-protocol-to-analyze-respiratory-chain-function-in-mouse-microglia/ Flow-cytometry-based protocol to analyze respiratory chain function in mouse microglia |... May 12, 2022 - Center for Basics in NeuroModulation flow cytometry https://www.research.va.gov/about/funded_research/proj-details-FY2022.cfm?pid=706843 I01BX005348-01A1 - Microglia-Vascular Interaction in Alteration of Blood-Retinal Barrier in... microgliavascularinteraction https://research.monash.edu/en/publications/minocycline-modulates-human-social-decision-making-possible-impac/ Minocycline modulates human social decision-making: possible impact of microglia on... decision makingminocyclinehumansocial https://www.frontiersin.org/journals/molecular-neuroscience/articles/10.3389/fnmol.2012.00074/full Frontiers | Microglia and Drug-Induced Plasticity in Reward-Related Neuronal Circuits Drugs of abuse result in complex changes in neurocircuit of reward and stress. Whilst most of these changes affect neurons, the role of additional cell types... frontiersmicrogliadruginduced https://publikationen.bibliothek.kit.edu/1000151929 Distribution of microglia/immune cells in the brain of adult z... Microglia are macrophage-like cells exerting determinant roles in neuroinflammatory and oxidative stress processes during brain regeneration. We used zebrafish in the brainimmune cellsdistributionmicrogliaadult https://www.frontiersin.org/journals/cellular-and-infection-microbiology/articles/10.3389/fcimb.2024.1367566/full Frontiers | Reconstitution of human microglia and resident T cells in the brain of humanized DRAGA... Humanized mouse models are valuable tools for investigating the human immune system in response to infection and injury. We have previously described the hum... https://infoscience.epfl.ch/entities/publication/1504d130-0ef8-48f0-832e-c5d33e5c10c1 Formation and maintenance of Alzheimer's disease beta-amyloid plaques in the absence of microglia In Alzheimer's disease, microglia cluster around beta-amyloid deposits, suggesting that these cells are important for amyloid plaque formation, maintenance... https://pubmed.ncbi.nlm.nih.gov/22046273/?dopt=Abstract Absence of colony stimulation factor-1 receptor results in loss of microglia, disrupted brain... The brain contains numerous mononuclear phagocytes called microglia. These cells express the transmembrane tyrosine kinase receptor for the macrophage growth... https://data.mendeley.com/datasets/tnfxthz5nd/1 Inflammatory, metabolic and sex-dependent gene-regulatory dynamics of resident microglia and... Codes were used to generate: motif analysis, differential expression and heatmaps analysing infiltrating macrophages and microglia in a neonatal mouse model of... inflammatorymetabolicsexdependent https://scholarshare.temple.edu/entities/publication/35c313f0-cceb-4f0f-a4a2-93e233609ffb Novel Scalable and Simplified System to Generate Microglia-Containing Cerebral Organoids From Human... Human cerebral organoid (CO) is a three-dimensional (3D) cell culture system that recapitulates the developing human brain. While CO has proved an invaluable... https://scholars.duke.edu/publication/735961 Scholars@Duke publication: Assessing activation states in microglia. scholarsdukepublicationassessingactivation https://sites.utexas.edu/inia-neuroimmune/2025/05/12/microglia-depletion-and-alcohol-transcriptome-and-behavioral-profiles/ Microglia depletion and alcohol: Transcriptome and behavioral profiles. microgliadepletionalcoholtranscriptomebehavioral https://www.sfb-trr167.uni-freiburg.de/publications/interaction-between-subventricular-zone-microglia-and-neural-stem-cells-impacts-the-neurogenic-response-in-a-mouse-model-of-cortical-ischemic-stroke/ Interaction between subventricular zone microglia and neural stem cells impacts the neurogenic... neural stem cells https://pmc.ncbi.nlm.nih.gov/articles/PMC20456/ Neurotrophins inhibit major histocompatibility class II inducibility of microglia: Involvement of... Major histocompatibility complex (MHC) molecules are rare in the healthy brain tissue, but are heavily expressed on microglial cells after inflammatory or... class iineurotrophinsinhibitmajormicroglia https://pubmed.ncbi.nlm.nih.gov/24397957/ Translocator protein (18 kDa) (TSPO) is expressed in reactive retinal microglia and modulates... These findings suggest that TSPO is highly expressed in reactive retinal microglia and a promising target to control microglial reactivity during retinal... https://refubium.fu-berlin.de/handle/fub188/9870?show=full Refubium - Essential role of actin filament dynamics in microglia activation essentialroleactinfilamentdynamics https://portal.fis.tum.de/en/publications/microglia-biology-one-century-of-evolving-concepts/ Microglia Biology: One Century of Evolving Concepts - Technical University of Munich one centurytechnical universitymicrogliabiologyevolving https://dibs.duke.edu/event/student-seminar-emily-alway-shocking-new-role-microglia-compulsive-sucrose-seeking/ Student Seminar: Emily Alway: A shocking new role of microglia in compulsive sucrose-seeking | Duke... Emily Alway is in Diego Bohorquez Lab. https://iris.cnr.it/handle/20.500.14243/178622 The isolectin IB4 binds RET receptor tyrosine kinase in microglia. tyrosine kinasebindsretreceptormicroglia https://www.frontiersin.org/journals/neurology/articles/10.3389/fneur.2023.989132/full Frontiers | Inhibiting microglia exacerbates the early effects of cuprizone in males in a rat model... Hyper-activity of the brain's innate immune cells, microglia, is a hallmark of multiple sclerosis (MS). However, it is not clear whether this involvement of ... https://hsrc.himmelfarb.gwu.edu/gwhpubs/3567/ "Isolation of Pure Astrocytes and Microglia from the Adult Mouse Spinal" by Julie J. Ahn, Robert H.... Astrocytes and microglia play pivotal roles in central nervous system development, injury responses, and neurodegenerative diseases. These highly dynamic cells... https://www.frontiersin.org/journals/aging-neuroscience/articles/10.3389/fnagi.2017.00227/full Frontiers | Microglia Responses in Acute and Chronic Neurological Diseases: What Microglia-Specific... Over the last decade, microglia have been acknowledged to be key players in central nervous system (CNS) under both physiological and pathological conditions... neurological diseasesfrontiersmicrogliaresponsesacute https://pure.psu.edu/en/publications/semaphorin4a-is-cytotoxic-to-oligodendrocytes-and-is-elevated-in-/ Semaphorin4A is cytotoxic to oligodendrocytes and is elevated in microglia and multiple sclerosis -... cytotoxic https://www.mdpi.com/1422-0067/26/5/2179 Novel Cell Models to Study Myelin and Microglia Interactions Multiple sclerosis (MS) is characterized by demyelination and neuroinflammation, with oxidative stress playing a pivotal role in lesion pathology. This study... cell modelsto studynovelmyelinmicroglia https://www.research.va.gov/about/funded_research/proj-details-FY2023.cfm?pid=705976 I01BX000963-09A1 - Role of Microglia in Protection Against West Nile Virus-induced CNS Injury:... https://www.neuromod.uni-freiburg.de/research/publications/microglia-states-and-nomenclature-a-field-at-its-crossroads/ Microglia states and nomenclature: A field at its crossroads | NeuroModulBasics Dec 12, 2022 - Center for Basics in NeuroModulation microgliastatesnomenclaturefieldcrossroads https://portal.research.lu.se/en/publications/inflammation-leads-to-distinct-populations-of-extracellular-vesic/ Inflammation leads to distinct populations of extracellular vesicles from microglia - Lund... extracellular vesiclesinflammationleadsdistinctpopulations https://oru.diva-portal.org/smash/record.jsf?pid=diva2:1850399 ARG1 expression in basal forebrain microglia modulates hippocampal innervation and cognition during... https://tobias-lib.uni-tuebingen.de/xmlui/handle/10900/55025 Homeostatic and injury-induced microglia behavior in the aging brain in theinjuryinducedmicrogliabehavior https://pubmed.ncbi.nlm.nih.gov/36787220/ Microglia reactivity entails microtubule remodeling from acentrosomal to centrosomal arrays Microglia reactivity entails a large-scale remodeling of cellular geometry, but the behavior of the microtubule cytoskeleton during these changes remains... microgliareactivitymicrotubuleremodelingarrays https://pubmed.ncbi.nlm.nih.gov/22736439/?dopt=Abstract Multiple P2Y subtypes in spinal microglia are involved in neuropathic pain after peripheral nerve... A prominent signaling pathway in the development of neuropathic pain involves ATP acting on microglial purinergic receptors. Among the P2Y metabotropic... https://events.manchester.ac.uk/event/event:abp-hqthusx8-lfcd4g/inmind-tspo-symposium-microglia-imaging-and-biology INMiND TSPO Symposium | Microglia Imaging and Biology | Events at The University of Manchester https://pubmed.ncbi.nlm.nih.gov/23832717/?dopt=Abstract Unique transcriptome signature of mouse microglia Microglial cells can be derived directly from the dissociated brain tissue by sorting procedures, from postnatal glial cultures by mechanic isolation or from... uniquetranscriptomesignaturemousemicroglia https://pubmed.ncbi.nlm.nih.gov/32808923/ Light-induced engagement of microglia to focally remodel synapses in the adult brain Microglia continuously monitor synapses, but active synaptic remodeling by microglia in mature healthy brains is rarely directly observed. We performed... https://vtechworks.lib.vt.edu/items/c842b8a2-ba7f-415a-bd55-e85bb3104845 Sex and region-specific effects of variable stress on microglia morphology Major Depressive Disorder (MDD) is a common and debilitating mood disorder that is more prevalent in women than men. In humans, PET imaging of microglia... region specificsexeffects https://cordis.europa.eu/project/id/101088437/results/es Microglia engineering and replacement to treat brain disease | ReplaceMi | Proyecto | Resultados |... Deliverables, publications, datasets, software, exploitable results brain diseasemicrogliaengineeringreplacement https://tobias-lib.ub.uni-tuebingen.de/xmlui/handle/10900/64603 Functional characterization of microglia in mouse models of Alzheimer's disease mouse modelsfunctionalcharacterizationmicrogliaalzheimer https://pubmed.ncbi.nlm.nih.gov/40480981/ GAS6/AXL signaling promotes M2 microglia efferocytosis to alleviate neuroinflammation in... Sepsis-associated encephalopathy (SAE) is a severe complication marked by acute central nervous system (CNS) injury and neuroinflammation. M2 microglia... axlsignalingpromotes https://portal.fis.tum.de/en/publications/de-novo-expression-of-dopamine-d2-receptors-on-microglia-after-st/ De novo expression of dopamine D2 receptors on microglia after stroke - Technical University of... https://portal.fis.tum.de/en/publications/loss-of-cln3-in-microglia-leads-to-impaired-lipid-metabolism-and-/ Loss of CLN3 in microglia leads to impaired lipid metabolism and myelin turnover - Technical... https://www.physiologie2.uni-tuebingen.de/node/413 Microglia colonize the developing brain by clonal expansion of highly proliferative progenitors,... the developing brain https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2018.01779/full Frontiers | Microglia in Health and Disease: A Unique Immune Cell Population Microglia are essential for the development and function of the adult brain. Their ontogeny, together with the absence of turnover from the periphery and the... health and diseaseimmune cellfrontiersmicroglia https://cordis.europa.eu/article/id/152115-immune-system-linked-to-neurodegeneration Immune system linked to neurodegeneration | MICROGLIA IN ALS Project | Results in Brief | FP7 |... A European study investigated the role of microglia, glial cells critical for immune response, on the progression of a rare... immune system https://www.frontiersin.org/journals/synaptic-neuroscience/articles/10.3389/fnsyn.2021.637549/full Frontiers | Poly I:C Activated Microglia Disrupt Perineuronal Nets and Modulate Synaptic Balance in... Perineuronal nets (PNNs) are specialized, reticular structures of the extracellular matrix (ECM) that can be found covering the soma and proximal dendrites o... https://pubmed.ncbi.nlm.nih.gov/39207402/ Galectin-9 Mediates the Functions of Microglia in the Hypoxic Brain Tumor Microenvironment Galectin-9 (Gal-9) is a multifaceted regulator of various pathophysiologic processes that exerts positive or negative effects in a context-dependent manner. In... https://www.sfb-trr167.uni-freiburg.de/projects/importance-of-microglial-tissue-surveillance-for-neural-development-and-function/ Decoding human microglia phenotypes in the context of neuropsychiatric disorders : SFB/TRR 167