https://pubmed.ncbi.nlm.nih.gov/30559476/
Microglia, the specialized innate immune cells of the CNS, play crucial roles in neural development and function. Different phenotypes and functions have been...
humanmicrogliaregionalheterogeneityphenotypes
https://pubmed.ncbi.nlm.nih.gov/34990615/?dopt=Abstract
Microglia, resident immune cells in the brain, are shown to mediate the crosstalk between psychological stress and depression. Interestingly, increasing...
in amouse modelphytoestrogengenisteinneuron
https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2022.863158/full
Microglia are the tissue-resident macrophages of the retina and brain, being critically involved in organ development, tissue homeostasis, and response to ce...
frontiers indepthmolecularprofilinghuman
https://pubmed.ncbi.nlm.nih.gov/37572655/
The limited efficacy of immunotherapies against glioblastoma underscores the urgency of better understanding immunity in the central nervous system. We found...
blockadeinducesmicrogliacellpartnership
https://pubmed.ncbi.nlm.nih.gov/29882317/?from_term=Fitzsimons+C&from_sort=date&from_page=2&from_pos=7
Microglia dynamically adapt their morphology and function during increasing age. However, the mechanisms behind these changes are to date poorly understood....
glucocorticoidmediatedmodulationmorphologicalchanges
https://www.omicsonline.org/peer-reviewed/preparation-and-characterization-of-microglialike-cells-derived-from-rat-mouse-and-human-bone-marrow-cells-for-therapeutic-strate-2962.html
Preparation and Characterization of Microglia-Like Cells Derived from Rat, Mouse, and Human Bone Marrow Cells for Therapeutic Strategy of Alzheimer's Disease...
preparationcharacterizationmicroglialikecells
https://pubmed.ncbi.nlm.nih.gov/27814300/?dopt=Abstract
In response to changes of the central nervous system environment, microglia are capable of acquiring diverse phenotypes for cytotoxic or immune regulation and...
rolesuppressorcytokinesignalingaltering
https://elifesciences.org/articles/90695/peer-reviews
Transplanted human iPSC-derived microglial cells with immune responses and phagocytic abilities integrate and occupy native microglial cell space and...
induced pluripotent stempeer reviewhumancellderived
https://www.frontiersin.org/journals/cell-and-developmental-biology/articles/10.3389/fcell.2024.1340308/full
Microglia are immune cells in the brain that originate from the yolk sac and enter the developing brain before birth. They play critical roles in brain devel...
in brainviral infectionfrontiersrolemicroglia
https://pubmed.ncbi.nlm.nih.gov/28076784/
Microglia play key roles in brain development, homeostasis, and function, and it is widely assumed that the adult population is long lived and maintained by...
the rapidcoupledproliferationapoptosismaintain
https://www.sciencedaily.com/releases/2005/04/050417213015.htm
Max Planck researchers shed light on the immune defense behaviour of microglial cells in the brain.
at workwatchingmicrogliasciencedaily
https://pubmed.ncbi.nlm.nih.gov/35463473/
Microglia and astrocytes are implicated in aging and age-related diseases. Here, we present a protocol to isolate and culture these glia cells from the murine...
isolationculturepureadultmouse
https://www.frontiersin.org/research-topics/28227/dysfunctional-microglia-in-neurological-disorders/magazine
Microglial cells play a key role in maintaining and regulating the homeostasis of the central nervous system (CNS). These cells respond to pathogens, injury,...
neurological disordersdysfunctionalmicrogliafrontiersresearch
https://elifesciences.org/articles/101630
MorphoCellSorter is a versatile, user-friendly tool that automates microglial morphology ranking, enabling standardized, reproducible analysis across diverse...
andrews plotbasedsortingapproachrank
https://pubmed.ncbi.nlm.nih.gov/35294256/
Hematopoietic cell transplantation after myeloablative conditioning has been used to treat various genetic metabolic syndromes but is largely ineffective in...
brain diseasetreatmentgeneticcnswide