https://www.frontiersin.org/journals/microbiology/articles/10.3389/fmicb.2020.559165/full
Within four months of the ongoing COVID-19 pandemic caused by SARS-CoV-2, more than 250 nucleotide mutations have been detected in ORF1ab of the virus isolat...
in thefrontierstranslationassociatedmutational
https://www.technologynetworks.com/cancer-research/videos/discovering-and-categorizing-mutational-signatures-from-cancer-whole-genomes-369791
Speaking at The Landscape of Cancer Research 2022 online symposium, Andrea Degasperi of the Early Cancer Institute, University of Cambridge, delivered his talk...
mutational signaturesdiscoveringcategorizingcancerwhole
https://pubmed.ncbi.nlm.nih.gov/31406485/
The recent advent of immunomodulatory therapies into the clinic has demanded the identification of innovative predictive biomarkers to identify patients most...
the clinictumormutationburdencomprehensive
https://www.frontiersin.org/journals/cell-and-developmental-biology/articles/10.3389/fcell.2021.661792/full
Background: There has limited treatment therapies for lung squamous cell carcinoma (LUSC). M6A related genes may be the next therapeutic targets for LUSC. In...
frontierscomprehensiveanalysisprognosticrole
https://www.sciencedaily.com/releases/2015/06/150608120141.htm
Researchers discovered previously uncharacterized mutational patterns in the human regulatory genome, especially in gastrointestinal tract cancers. Unraveling...
regulatory elementsnovelmutationalprocesstargeting
https://www.frontiersin.org/journals/cellular-and-infection-microbiology/articles/10.3389/fcimb.2024.1381155/full
Kinetoplastid pathogens including Trypanosoma brucei, T. cruzi, and Leishmania species, are early diverged, eukaryotic, unicellular parasites. Functional und...
rnase iiifrontiersdeepmutationalscanning
https://www.prnewswire.com/news-releases/seracare-life-sciences-launches-first-ever-tumor-mutational-burden-reference-materials-300949277.html
/PRNewswire/ -- SeraCare Life Sciences, part of the LGC Clinical Diagnostics Business Unit and a manufacturer and leading partner to global in vitro...
tumor mutational burdenlife sciencesfirst everlaunchesreference
https://elifesciences.org/articles/67806
Mapping mutations affecting gene expression within the yeast genome and within a gene regulatory network reveals properties of the raw material for regulatory...
of transgene expressionmutationalsourcesregulatory