Robuta

enzyme complex of which the core is a heterodimer composed of a light (alpha) and heavy (beta) chain, and requires several other water-soluble proteins of...

In normal kidneys the renal medulla very efficiently converts arachidonic acid to prostaglandins. Although the renal cortex has only trace amounts of...

Genomic alterations of tumor suppressorsoften encompass collateral protein-coding genes that create therapeutic vulnerability to further inhibition of their...

Crystal structure of Gox0644 in complex with NADPH

Dihydrofolate reductase5-[3-(2,5-dimethoxyphenyl)prop-1-yn-1-yl]-6-ethylpyrimidine-2,4-diamineNADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE

FAD-binding FR-type domain-containing protein1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDEFLAVIN-ADENINE DINUCLEOTIDEPROTOPORPHYRIN IX CONTAINING FE

We provide evidence that dopaminergic neurons are equipped with the Nox1/Rac1 superoxide-generating system. Stress-induced Nox1/Rac1 activation causes...

Actinorhodin Polyketide Ketoreductase Mutant P94L bound to NADPH

For a long time, superoxide generation by an NADPH oxidase was considered as an oddity only found in professional phagocytes. Over the last years, six homologs...

Dihydrofolate reductase6-ethyl-5-[3-(4-methoxybiphenyl-3-yl)prop-1-yn-1-yl]pyrimidine-2,4-diamineNADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE

Malate dehydrogenase2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOLNADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE

Light-dependent protochlorophyllide reductaseCHLORIDE IONNADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE

Two major complexes of NADPH dehydrogenase (NDH-1) have been identified in cyanobacteria. A large complex (NDH-1L) contains NdhD1 and NdhF1, which are absent...

Actinorhodin Polyketide Ketoreductase, with NADPH bound