https://ricerca.uniba.it/handle/11586/350602
Targeting SMYD3 to Sensitize Homologous Recombination-Proficient Tumors to PARP-Mediated Synthetic...
homologous recombinationtargetingproficienttumorsparp
https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2022.971369/full
Frontiers | A multi-task FP-GNN framework enables accurate prediction of selective PARP inhibitors
PARP (poly ADP-ribose polymerase) family is a crucial DNA repair enzyme that responds to DNA damage, regulates apoptosis, and maintains genome stability; the...
accurate predictionparp inhibitorsfrontiersmultitask
https://www.benthamscience.com/article/91932
Kinase Phosphorylation-based Mechanisms of PARP Inhibitor Resistance During Synthetic Lethal...
Background: Poly-(ADP-Ribose) Polymerase (PARP) plays a central role in recovery from single-strand DNA (ssDNA) damage via base excision repair. When P
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https://www.custommarketinsights.com/report/parp-inhibitors-market/
Global PARP Inhibitors Market Size, Trends, Share 2033
The Global PARP Inhibitors Market size was valued at $8.4 Billion in 2024 and it will grow $23.5 Billion at a CAGR of 12.1% by 2024 to 2033
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https://apcz.umk.pl/JEHS/article/view/57677
PARP Inhibitors in the Treatment of Ovarian Cancer: a review of the latest research | Journal of...
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https://www.cancer.gov/news-events/cancer-currents-blog/2017/idh-mutation-parp
PARP Inhibitors for Cancers with IDH Mutations - NCI
A Cancer Currents blog on studies that suggest brain and other cancers with an IDH mutation are susceptible to treatment with PARP inhibitors, such as olaparib.
parp inhibitorscancersidhmutationsnci
https://pubmed.ncbi.nlm.nih.gov/31127309/?dopt=Abstract
Restriction of AID activity and somatic hypermutation by PARP-1
Affinity maturation of the humoral immune response depends on somatic hypermutation (SHM) of immunoglobulin (Ig) genes, which is initiated by targeted lesion...
restrictionaidactivitysomaticparp
https://uroweb.org/education-events/urowebinar-parp-inhibitors-in-prostate-cancer-part-1
UROwebinar: PARP inhibitors in prostate cancer. Part 1 - Uroweb
European Association of Urology - To raise the level of urological care. The EAU represents the leading authority within Europe on urological practice,...
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https://ecancer.org/en/video/8304-profound-parp-inhibitor-olaparib-compared-with-new-hormonal-agents-in-advanced-castration-resistant-prostate-cancer
PROfound: PARP inhibitor olaparib compared with new hormonal agents in advanced castration...
Prof Maha Hussain speaks to ecancer at ESMO 2019 in Barcelona about data from the PROfound trial comparing the PARP inhibitor olaparib with new hormonal agen
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https://www.repository.cam.ac.uk/items/788de607-5de3-4825-b4c6-0d525b46ac6f
Chlorambucil targets BRCA1/2-deficient tumours and counteracts PARP inhibitor resistance.
Due to compromised homologous recombination (HR) repair, BRCA1- and BRCA2-mutated tumours accumulate DNA damage and genomic rearrangements conducive of tumour...
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https://www.rcsb.org/structure/6XVW
RCSB PDB - 6XVW: Catalytic domain of human PARP-1 in complex with the inhibitor MC2050
Catalytic domain of human PARP-1 in complex with the inhibitor MC2050
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https://www.bioworld.com/articles/701730-slap-pharmaceuticals-divulges-new-parp-1-inhibitors-for-cancer?v=preview
Slap Pharmaceuticals divulges new PARP-1 inhibitors for cancer | BioWorld
Slap Pharmaceuticals LLC have identified new poly(ADP-ribose) polymerase 1 (PARP-1; ARTD1) inhibitors reported to be useful for the treatment of cancer.
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https://researchexperts.utmb.edu/en/publications/polyadp-ribose-polymerase-1-parp-1-transcriptionally-regulates-an/
Poly(ADP-ribose) polymerase-1 (PARP-1) transcriptionally regulates angiotensin AT2 receptor (AT2R)...
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https://campus-fryslan.studenttheses.ub.rug.nl/372/
Hubert wins the lottery PARP(-P) pruning the HuBERT model for downstream tasks - Studenttheses...
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https://fair.unifg.it/handle/11369/468399
Personalized medicine for metastatic prostate cancer: The paradigm of PARP inhibitors
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https://alfagen.com.tr/product/mouse-poly-adp-ribose-polymerase-parp-elisa-kit/
Mouse Poly ADP Ribose Polymerase (PARP) ELISA Kit - ALFAGEN
PARP1; ADPRT; ADPRT1; PPOL; pADPRT-1; ADP-ribosyltransferase diphtheria toxin-like 1; NAD(+) ADP-ribosyltransferase 1
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https://www.jadpro.com/cme-supplements/volume-8-supplement-3-oct-2017/brca-related-ovarian-cancers-and-the-role-of-parp-inhibitor-therapy/
JADPRO | BRCA-Related Ovarian Cancers and the Role of PARP Inhibitor Therapy
role ofparp inhibitorbrcarelatedovarian
https://www.bopa.org.uk/resources/description-of-a-pharmacist-led-parp-inhibitor-clinic-for-patients-with-ovarian-cancer-in-nova-scotia-canada/
Description of a Pharmacist-led PARP Inhibitor Clinic for Patients with Ovarian Cancer in Nova...
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parp inhibitorfor patientsovarian cancerdescriptionpharmacist
https://christie.openrepository.com/entities/publication/0255f1f3-8ea6-4e79-b09c-76463dd7713b
A multi-centre phase I trial of the PARP inhibitor olaparib in patients with relapsed chronic...
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https://massivebio.com/parp-1-inhibitor-abt-888-bio/
Parp 1 Inhibitor Abt 888
Dec 1, 2025 - Discover what Parp 1 Inhibitor Abt 888 is: an experimental compound scientists are investigating for its potential role in cancer therapy.
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https://hub.tmu.edu.tw/zh/publications/targeted-parp-inhibition-combined-with-fgfr1-blockade-is-syntheti/
Targeted PARP Inhibition Combined with FGFR1 Blockade is Synthetically Lethal to Malignant Cells in...
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https://bulios.com/ticker/PARP.PA
Groupe Partouche SA (PARP.PA) Stock | PARP.PA Stock Price & Analysis - Bulios
Get the latest news and market analysis for Groupe Partouche SA (PARP.PA). Stay up-to-date on PARP.PA Stock price and share price with Bulios. Explore our...
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https://consultqd.clevelandclinic.org/promise-parp-inhibitors-brca1brca2-cancers
Promise of PARP Inhibitors for BRCA1/BRCA2 Cancers
Two new clinical trials are evaluating olaparib therapy for women with metastatic breast cancer and stage II/III breast cancers marked by BRCA1/BRCA2 mutations...
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https://meetings.cshl.edu/galleries/viewer.asp?directory=parp24&offset=380
The PARP Family & ADP-ribosylation
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https://ocw.mit.edu/courses/20-380j-biological-engineering-design-spring-2010/external-resources/activation-of-polyadp-ribose-polymerase-parp-1-induces-release-of-the-pro-inflammatory-me9b548691-8347-4643-aeaf-671ac1bab9b0/
Activation of Poly(ADP)-Ribose Polymerase (PARP-1) Induces Release of the Pro-Inflammatory Mediator...
MIT OpenCourseWare is a web based publication of virtually all MIT course content. OCW is open and available to the world and is a permanent MIT activity
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https://www.birminghammedicalnews.com/tags/367/parp-inhibitors
PARP inhibitors - Birmingham Medical News
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https://pure.fujita-hu.ac.jp/en/publications/a-subset-of-parp-inhibitors-induces-lethal-telomere-fusion-in-alt/
A subset of PARP inhibitors induces lethal telomere fusion in ALT-dependent tumor cells - Fujita...
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https://unige.iris.cineca.it/handle/11567/1260456
Assessing Determinants of Response to PARP Inhibition in Germline ATM Mutant Melanoma
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https://avesis.hacettepe.edu.tr/yayin/df2a4ffb-4e38-4c8d-95eb-09e87f1ec393/outcomes-of-first-line-parp-inhibitor-therapy-in-ovarian-cancer-a-multicenter-retrospective-analysis
Outcomes of First-Line PARP Inhibitor Therapy in Ovarian Cancer: A Multicenter Retrospective...
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https://www.aging-us.com/article/202152
Comparative efficacy, safety, and acceptability of single-agent poly (ADP-ribose) polymerase (PARP)...
Background: Breast cancer is the most commonly diagnosed cancer and is the leading cause of cancer death in women worldwide. Both talazoparib and olaparib are...
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https://www.canceropole-est.org/la-recherche-au-sein-du-canceropole-est/annuaires/publications-scientifiques/detail/?id=45602
Prevention and management of PARP inhibitor-related haematological toxicities in prostate cancer:...
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https://www.polishconstitution.org/shop/0622-4684-096-k-ht-colorimetric-parp-apoptosis-assay-kit-96t-7558
HT Colorimetric PARP Apoptosis Assay Kit 96T | polishconstitution
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https://www.pharmiweb.com/press-release/2021-05-07/china-nmpa-approves-parp-inhibitor-pamiparib-for-patients-with-previously-treated-advanced-ovarian-c
China NMPA Approves PARP Inhibitor Pamiparib for Patients with Previously Treated Advanced Ovarian...
Pamiparib becomes the first PARP inhibitor approved in both platinum-sensitive and platinum-resistant relapsed ovarian cancer in ChinaThis marks the first...
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https://blog.dana-farber.org/insight/2025/06/double-negative-in-cells-could-undermine-parp-inhibitors/
Double Negative in Cells Could Undermine PARP Inhibitors | Dana-Farber Cancer Institute
Jun 11, 2025 - Published: June 10, 2025Updated: June 11, 2025Written by: Beth DoughertyThere are two ways to fix things: the quick way and the careful one. In cancer, cells...
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https://blurbfromtheburbs.blogspot.com/2013/02/putta-putta-putta-parp.html
Blurb from the Burbs: Putta putta putta PARP!
Regular readers will know that I fart (often) and ain't afraid to admit it. The relief of being open about this might be a reaction to the...
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https://www.mdanderson.org/newsroom/archived-news/parp-inhibitor-improves-progression-free-survival-in-patients-with-advanced-breast-cancers-and-BRCA-mutations.h00-159150768.html
ARCHIVED: PARP inhibitor improves progression-free survival in patients with advanced breast...
In a randomized, Phase III trial led by researchers at The University of Texas MD Anderson Cancer Center, the PARP inhibitor talazoparib extended...
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https://eatris.cz/publication/impact-factor-journals/therapeutic-targeting-constitutive-parp-activation-compromises?language_content_entity=en&language=cs
Therapeutic targeting of constitutive PARP activation compromises stem cell phenotype and survival...
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https://gasmaskrespirator.com/2026/03/08/scott-sea-se400-powered-full-gas-mask-respirator-system-parp-se-400at-2-4/
Gas Mask Respirator | Scott / SEA SE400 Powered Full Gas Mask Respirator System PARP SE-400AT-2
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https://www.fiercebiotech.com/research/how-parp-inhibitors-might-prove-useful-more-than-just-brca-cancers
How PARP inhibitors might prove useful in more than just BRCA cancers | Fierce Biotech
Jul 26, 2017 - PARP inhibitor Lynparza (olaparib) has been embraced by oncologists treating women with BRCA-mutant ovarian cancer, and the AstraZeneca drug is also showing...
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https://scholars.houstonmethodist.org/en/publications/widespread-increased-expression-of-the-dna-repair-enzyme-parp-in-/
Widespread increased expression of the DNA repair enzyme PARP in brain in ALS - Houston Methodist...
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https://www.certara.com/poster/predicting-the-concentration-of-parp-inhibitors-in-human-tumor-tissue-using-pbpk-modeling/
Predicting the Concentration of PARP Inhibitors in Human Tumor Tissue Using PBPK Modeling | Certara
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https://repub.eur.nl/pub/41135
RePub, Erasmus University Repository: Distinct spatiotemporal patterns and PARP dependence of XRCC1...
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https://elifesciences.org/reviewed-preprints/91482v1
PARP-1 cooperates with histone methyltransferase to regulate transcription
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https://franceheadlines.com/alfa-cytology-starts-comprehensive-development-services-for-parp-inhibitors-aimed-at-advanced-cancer-treatment/
Alfa Cytology Starts Comprehensive Development Services for PARP Inhibitors Aimed at Advanced...
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https://silice.es/publication/0149ae31-acae-4f2a-b919-d1c01a5d9e50
Long-term outcomes of PARP inhibitors in ovarian cancer: survival, adverse events, and...
Poly-ADP-ribose polymerase inhibitors (PARPis) have revolutionized the management of BRCA-mutated (BRCA
long termparp inhibitorsovarian canceradverse eventsoutcomes
https://idr.nitk.ac.in/items/af0b44aa-368c-49cb-b58d-69a5b84c2ea5
Theoretical insights into molecular mechanism and energy criteria of PARP-2 enzyme inhibition by...
The emergence of poly (ADP-ribose) polymerase (PARP) inhibitors targeting a class of PARP enzymes has gained a great interest in cancer therapy. Majority of...
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https://ogkologos.com/elucidating-a-risk-of-developing-second-primary-malignancy-during-and-after-treatment-with-parp-inhibitors/
Elucidating a Risk of Developing Second Primary Malignancy During and After Treatment with PARP...
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https://premiersreadingchallenge.sa.edu.au/books/the-super-parp-buster/
The Super Parp-buster | Premiers Reading Challenge SA
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https://www.mednous.com/developing-radionuclide-parp-inhibitors
Developing radionuclide PARP inhibitors | MedNous
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https://boa.unimib.it/handle/10281/506079
Distribution of pamiparib, a novel inhibitor of poly(ADP-ribose)-polymerase (PARP), in tumor tissue...
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https://log24.pl/tag/parp/
parp - Log24.pl
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https://cris.biu.ac.il/en/publications/ca-sup2sup-induced-parp-1-activation-and-anf-expression-are-coupl/
Ca 2+-induced PARP-1 activation and ANF expression are coupled events in cardiomyocytes -...
caparpactivationanfexpression
https://iris.unito.it/handle/2318/2030911
Homologous Recombination deficiency classification and PARP inhibitor response of reference-free...
homologous recombinationparp inhibitordeficiencyclassificationresponse
https://www.sciencedaily.com/releases/2011/03/110308124918.htm
Role of PARP enzyme in eukaryotes | ScienceDaily
A molecular biologist leveraged a supercomputer to help better define the family tree of a group of enzymes that have been implicated in a wide range of human...
role ofparpenzymeeukaryotessciencedaily
https://liducks.com/ducks-help-kick-off-parp-week/
DUCKS HELP KICK OFF PARP WEEK
DUCKS HELP KICK OFF PARP WEEK
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https://ag.purdue.edu/events/department/btny/ppp/2026/06/posey-county-southwest-district1.html
Posey County Cover Crops Breakfast PARP - Southwest District
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https://www.thesolver.it/ricercatori-individuano-in-che-modo-gli-inibitori-di-parp-combattono-le-cellule-tumorali-brca1-e-brca2/
Ricercatori individuano in che modo gli inibitori di PARP combattono le cellule tumorali BRCA1 e...
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https://experts.umn.edu/en/publications/direct-quantitation-of-polyadp-ribose-polymerase-parp-activity-as/
Direct quantitation of poly(ADP-Ribose) polymerase (PARP) activity as a means to distinguish...
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https://absave.com/products/cleaved-parp-monoclonal-antibody-abm40145
Cleaved PARP Monoclonal Antibody by Abbkine Scientific Co.Ltd. - Absave
Cleaved PARP Monoclonal Antibody - Read User Reviews, Features, Research Applications and get the Best Price/Quote
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https://mambiznes.pl/tag/parp/
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https://acir.org/weekly-digests/2021/january/focus-on-suppressive-macrophages-may-boost-effects-of-parp-inhibitors
Focus on suppressive macrophages may boost effects of PARP inhibitors
Mehta et al. researched the mechanisms behind resistance to PARP inhibition in BRCA1-mutant breast cancer. Using single-cell and multi-omics profiling, they...
focus onparp inhibitorsmacrophagesmayboost
https://www.consultant360.com/exclusive/high-tumor-mutational-burden-may-boost-parp-inhibitor-response-brca-mutant-cancers
High Tumor Mutational Burden May Boost PARP Inhibitor Response in BRCA-Mutant Cancers |...
A retrospective analysis presented at the American Society of Clinical Oncology 2025 Annual Meeting suggests that higher tumor mutational burden (TMB) may be...
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https://scienmag.com/tag/overcoming-resistance-to-parp-inhibitors/
overcoming resistance to PARP inhibitors | Science
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