https://brcageneawareness.org/
BRCA Gene Awareness
Raising public awareness and support in the battle against breast and ovarian cancer
brca geneawareness
https://pubmed.ncbi.nlm.nih.gov/21990165/
Classification of missense substitutions in the BRCA genes: a database dedicated to Ex-UVs
Unclassified sequence variants (UVs) arising from clinical mutation screening of cancer susceptibility genes present a frustrating issue to clinical genetics...
https://experts.arizona.edu/en/publications/brca-1-promoter-hypermethylation-and-silencing-induced-by-the-aro/
BRCA-1 promoter hypermethylation and silencing induced by the aromatic hydrocarbon receptor-ligand...
https://www.cancer.gov/about-cancer/causes-prevention/genetics/brca-fact-sheet
BRCA Gene Changes: Cancer Risk and Genetic Testing Fact Sheet - NCI
A fact sheet about the BRCA1 and BRCA2 genes, what to do if a person tests positive for alterations in one of these genes, and consequences of genetic testing.
brca genecancer riskgenetic testingfact sheetchanges
https://pure.psu.edu/en/projects/brca-1-function-using-an-inducible-transgene-5/
BRCA 1 FUNCTION USING AN INDUCIBLE TRANSGENE - Penn State
brcafunctionusingtransgenepenn
https://www.frontiersin.org/journals/genetics/articles/10.3389/fgene.2021.674094/full
Frontiers | Characteristics of Germline Non-BRCA Mutation Status of High-Risk Breast Cancer...
Background: Expert consensus on BRCA1/2 genetic testing and clinical application in Chinese breast cancer patients recommends that BRCA1/2 testing should be ...
https://herenciageneticayenfermedad.blogspot.com/2018/02/brca-mutations_31.html
herenciageneticayenfermedad: BRCA MUTATIONS
brcamutations
https://cancer.osu.edu/blog/brca-mutation-leads-to-action-and-advocacy-for-genetic-testing
BRCA Mutation Leads to Action, Advocacy for Genetic Testing
First came surprise; then came action. A James patient took a proactive approach to breast cancer prevention after discovering the presence of a BRCA mutation.
brcamutationleadsactionadvocacy
https://goodbrcagenes.org/
עמותת גנים טובים - קהילת נשאיות ונשאי BRCA - גנים טובים
Oct 19, 2025 - עמותה למען נשאיות ונשאי גנים BRCA 1 ו- BRCA 2 המהווה קהילה תומכת, אשר מספקת מענה, סיוע ומידע מקיף אודות מוטציות בגן BRCA, הקשורות בסיכון יתר לסרטן שד ושחלה.
brca
https://news.cancerresearchuk.org/2024/01/25/talazoparib-brca-genes-targeted-advanced-breast-cancer-treatment-nhs/
NHS offers first drug targeting advanced breast cancers driven by BRCA gene mutations - Cancer...
Jan 21, 2026 - Around 300 people in England can receive talazoparib, which can stop advanced breast cancers with BRCA gene mutations growing for longer.
https://www.aafp.org/about/news/20190306uspstf-brcatest
USPSTF: Screen At-risk Women for BRCA-related Cancer | AAFP
The U.S. Preventive Services Task Force recently posted for comment a draft recommendation statement and draft evidence review on risk assessment, genetic...
at riskuspstfscreenwomenbrca
https://pubmed.ncbi.nlm.nih.gov/25789811/
Genotype-Phenotype Correlations by Ethnicity and Mutation Location in BRCA Mutation Carriers
The genotype-phenotype correlations of the specific BRCA1 and BRCA2 mutations in multi-ethnic populations in USA have not yet been fully investigated. This...
by ethnicitygenotypephenotypecorrelations
https://www.yorku.ca/osgoode/iposgoode/2009/11/25/brca-gene-patents-lawsuit-lives-on/
BRCA Gene Patents Lawsuit Lives On - IPOsgoode
Nov 25, 2009 - George Nathanael is a JD Candidate at Osgoode Hall Law School. Earlier this month a United States District Court denied a motion to dismiss a lawsuit brought...
brca genepatentslawsuitlives
https://academiccommons.columbia.edu/doi/10.7916/d8-6j28-2t98
Promoter Hypermethylation of FANCF: Disruption of Fanconi Anemia-BRCA Pathway in Cervical Cancer |...
Patients with advanced stage invasive cervical cancer (CC) exhibit highly complex genomic alterations and respond poorly to conventional treatment protocols....
fanconi anemia
https://eprints.ncl.ac.uk/288410
Efficacy and safety of rucaparib treatment in patients with BRCA-mutated, relapsed ovarian cancer:...
efficacy and safety
https://brcachat.com/
BRCA Chat | Genetic Breast & Ovarian Cancer Support
ovarian cancerbrcachatgeneticbreast
https://www.brcani.co.uk/
BRCA Link NI | Support & Information
brcanisupportinformation
https://pubmed.ncbi.nlm.nih.gov/23810788/
The poly(ADP-ribose) polymerase inhibitor niraparib (MK4827) in BRCA mutation carriers and patients...
Merck Sharp and Dohme.
https://scholarsarchive.byu.edu/facpub/5100/
"Hereditary Cancer Syndrome Recognition and Testing: Beyond BRCA" by Deborah O. Himes and Hanford...
Hereditary cancer syndromes, resulting from mutations of tumor suppressor genes, can significantly increase the risk for breast cancer. Although hereditary...
https://www.health.harvard.edu/blog/researchers-urge-prostate-cancer-screening-for-men-with-brca-gene-defects-2019122018615
Researchers urge prostate cancer screening for men with BRCA gene defects - Harvard Health
Dec 20, 2019 - Prostate cancer screening with the prostate-specific antigen (PSA) test has been criticized for flagging too many slow-growing tumors that might never be...
prostate cancer screening
https://pubmed.ncbi.nlm.nih.gov/31157963/?dopt=Abstract
Maintenance Olaparib for Germline BRCA-Mutated Metastatic Pancreatic Cancer
maintenanceolaparibgermlinebrcamutated
https://liu.diva-portal.org/smash/record.jsf?faces-redirect=true&language=sv&searchType=SIMPLE&query=&af=%5B%5D&aq=%5B%5B%5D%5D&aq2=%5B%5B%5D%5D&aqe=%5B%5D&pid=diva2%3A1890784&noOfRows=50&sortOrder=author_sort_asc&sortOrder2=title_sort_asc&onlyFullText=false&sf=all
Gray matter volume in women with the BRCA mutation with and without ovarian removal: evidence for...
https://pubmed.ncbi.nlm.nih.gov/15996267/
Familial breast cancer: characteristics and outcome of BRCA 1-2 positive and negative cases
Although BRCA positive patients have more frequently negative prognostic factors, their prognosis appears to be equal to or better than in patients with...
familial breast cancer
https://eprints.ncl.ac.uk/182656
Poly(ADP-ribose) polymerase inhibition: a new direction for BRCA and triple-negative breast cancer?...
https://www.nhsjewishbrcaprogramme.org.uk/
J-BRCA
jbrca
https://www.wikidata.org/wiki/Q33820594
Two decades after BRCA: setting paradigms in personalized cancer care and prevention - Wikidata
personalized cancer care
https://sciencedaily.com/releases/2021/06/210604122711.htm
New findings offer improved therapy of early-stage, BRCA mutation-associated breast cancer |...
A new treatment has potential to improve the outcomes for patients with hereditary BRCA mutations and high-risk, early-stage breast cancer. These results...
https://pubmed.ncbi.nlm.nih.gov/16030099/
Prevalence of BRCA mutations and founder effect in high-risk Hispanic families
This is the largest study to date of high-risk Hispanic families in the United States. Six recurrent mutations accounted for 47% (16 of 34) of the deleterious...
brca mutationsfounder effect
https://www.frontiersin.org/journals/oncology/articles/10.3389/fonc.2014.00042/full
Frontiers | Beyond Breast and Ovarian Cancers: PARP Inhibitors for BRCA Mutation-Associated and...
Poly(ADP-ribose) polymerase inhibitors (PARPi) have shown clinical activity in patients with germline BRCA1/2 mutation (gBRCAm)-associated breast and ovarian...
https://tywkiwdbi.blogspot.com/2013/07/notes-about-brca-gene-mutation-and.html
TYWKIWDBI ("Tai-Wiki-Widbee"): Notes about the BRCA gene mutation and breast cancer
From links bookmarked during the publicity surrounding Angelina Jolie's elective double mastectomy. First, from a Reddit AskScience thread...
https://cancerchat.cancerresearchuk.org/f/moving-on/126497/lumps-after-mastectomy-brca-2
Lumps after Mastectomy. BRCA 2 - Moving on - Cancer Chat | Cancer Research UK
Hi, I had a preventative mastectomy in 2015 due to Brca2. Mother and sister both had cancer. Found a large painless lump a few weeks ago and then this weekend
moving onlumpsmastectomybrca
https://brca.ucsf.edu/family-planning
Family Planning | Center for BRCA Research
family planningcenter forbrcaresearch
https://mlabs.umich.edu/tests/brca-gene-sequencing
BRCA Gene Sequencing | MLabs
brca genesequencingmlabs
https://pmc.ncbi.nlm.nih.gov/articles/PMC2276233/
Phenylbutyrate interferes with the Fanconi anemia and BRCA pathway and sensitizes head and neck...
Cisplatin has been widely used to treat head and neck cancer. One of the clinical limitations with this treatment, however, is that tumors that are initially...
fanconi anemia
https://hspop.uw.edu/publication/trends-in-brca-test-utilization-in-an-integrated-health-system-2005-2015/
Trends in BRCA Test Utilization in an Integrated Health System, 2005-2015. - Health Systems and...
Knerr S, Bowles EJA, Leppig KA, Buist DSM, Gao H, Wernli KJ. Trends in BRCA Test Utilization in an Integrated Health System, 2005-2015. J Natl Cancer Inst....
https://coffeeandchemo.blogspot.com/2009/03/brca-genes-how-do-they-fit.html?showComment=1237915440000
Coffee and Chemo: BRCA Genes -- How Do They Fit?
Have you been tested for the BRCA gene mutation? If so, a local journalist is interested in interviewing you! Please contact Laura Kusisto a...
how docoffeechemobrcagenes
https://about.ebsco.com/clinical-decisions/dynamed-solutions/about/ebm-focus/prophylactic-oophorectomy-associated-reduced
Prophylactic Oophorectomy Associated with Reduced Mortality and Ovarian Cancer in Women with BRCA...
associated with
https://news.cancerresearchuk.org/2025/05/13/partner-brca-breast-cancer-treatment-olaparib-chemotherapy/
Partnering olaparib with chemotherapy helps treat BRCA breast cancers - Cancer Research UK - Cancer...
May 15, 2025 - Our PARTNER trial has found a new way to treat inherited breast cancers linked to BRCA mutations, and reported 100% survival.
https://www.cancer.gov/news-events/press-releases/2019/brca-exchange
BRCA Exchange serves as global data resource on gene variants - NCI
The BRCA Exchange, a global resource that includes data on thousands of variants in the BRCA1 and BRCA2 genes, is available to the public through a website and...
global databrcaexchangeserves
https://scholars.duke.edu/grant/235198
Scholars@Duke grant: BRCA 1 and BRCA2 missense mutations and breast cancer risk
https://documents.worldbank.org/en/publication/documents-reports/documentdetail/099072424110040360/p176068131c2a4321cbd6148751a0ba1d244d657554e
Building Regulatory Capacity Assessment : BRCA 2.0 Methodology
The Building Regulatory Capacity Assessment (BRCA) is a methodology to help countries, and cities assess their building and land use regulatory framework and...
capacity assessmentbuildingregulatorybrcamethodology
https://brca.ucsf.edu/media
In the Media | Center for BRCA Research
in the mediacenter forbrcaresearch
https://pubmed.ncbi.nlm.nih.gov/36614207/
The Role of Hormonal Replacement Therapy in BRCA Mutated Patients: Lights and Shadows
All cancers develop as a result of mutations in genes. DNA damage induces genomic instability and subsequently increases susceptibility to tumorigenesis. Women...
hormonal replacement therapy
https://www.jstage.jst.go.jp/article/kjm/advpub/0/advpub_2024-0019-RE/_html
Mental Health Care among Cancer Patients with BRCA Gene Mutations: The Potential of...
Access full-text academic articles: J-STAGE is an online platform for Japanese academic journals.
mental health care
https://brcanetwork.be/
Home - BRCA+ Network
Dec 22, 2025 - Welcome, Bienvenue, Welkom! The Belgian NGO that supports, advocates and informs about genetic predispositions to breast and ovarian cancer.
brcanetwork
https://www.graybrcaatlas.org/
Gray BRCA Pre-Cancer Atlas | The Gray BRCA Pre-Cancer Atlas seeks to transform treatment and...
Apr 23, 2026 - ADVANCING CANCER RESEARCH
cancer atlasgraybrcapre
https://brcaexchange.org/
BRCA Exchange
brcaexchange
https://doorlesscarp953.substack.com/p/s2-subunit-of-sars-ncov-2-interacts?open=false
Tumor Suppressor Protein p53 & BRCA related cancers
Experimental gene therapy transfections and public health implications
tumorsuppressorproteinbrcarelated
https://www.frontiersin.org/journals/oncology/articles/10.3389/fonc.2025.1507840/full
Frontiers | Part II: consensus statements and expert recommendations for BRCA-associated breast...
IntroductionExisting guidelines have practical gaps in decision and treatment sequencing for BRCA germline pathogenic variant breast cancers. This paper aims...
part iiconsensus statements
https://sweetremedyfilm.blogspot.com/2012/09/tsa-naked-body-scanners-could-prove.html
Sweet Remedy: TSA naked body scanners could prove extra harmful to women with BRCA gene
Natural News Women who possess the BRCA gene, the mutations of which are linked to so-called hereditary breast and ovarian cancers, may ...
https://pubmed.ncbi.nlm.nih.gov/28792849/
Olaparib for Metastatic Breast Cancer in Patients with a Germline BRCA Mutation
Olaparib for Metastatic Breast Cancer in Patients with a Germline BRCA Mutation
metastatic breast cancerin patients
https://pubmed.ncbi.nlm.nih.gov/18779615/
Clinical and pathologic characteristics of patients with BRCA-positive and BRCA-negative breast...
These results suggest that tumors associated with BRCA1 mutations may be divided into two distinct groups, triple-negative and non-triple-negative groups....
clinicalpathologiccharacteristics
https://brca.ucsf.edu/contact-us
Contact Us | Center for BRCA Research
center forusbrcaresearch
https://scholarshare.temple.edu/entities/publication/2de2873e-b0fb-4754-9f36-ec19589f722f
Simultaneous Targeting of PARP1 and RAD52 Triggers Dual Synthetic Lethality in BRCA-Deficient Tumor...
PARP inhibitors (PARPis) have been used to induce synthetic lethality in BRCA-deficient tumors in clinical trials with limited success. We hypothesized that...
https://brca.ucsf.edu/current-research
Current Research | Center for BRCA Research
current researchcenter forbrca
https://www.thedearboobsproject.com/
Letters to boobs after breast cancer or BRCA surgery | The Dear Boobs Project
The Dear Boobs Project. Letters to boobs after breast cancer or BRCA surgery. | Share Wisdom | Inspire Healing | Celebrate Community |...
after breast cancer
https://researchprofiles.ku.dk/da/publications/iad-hoci-analysis-of-the-phase-iii-engot-ov16nova-study-niraparib/
Ad hoc Analysis of the Phase III ENGOT-OV16/NOVA Study: Niraparib Efficacy in Germline BRCA...
https://eprints.ncl.ac.uk/261702
Why BRCA mutations are not tumour-agnostic biomarkers for PARP inhibitor therapy - ePrints -...
https://www.brcacenter.com/
New York BRCA Center - The First Comprehensive BRCA Center in NYC
The First Comprehensive BRCA Center in NYC.
new yorkthe firstbrcacentercomprehensive
https://www.mdpi.com/2072-6694/14/23/5769
Should Preimplantation Genetic Testing (PGT) Systematically Be Proposed to BRCA Pathogenic Variant...
Over the past years, BRCA genes pathogenic variants have been associated to reproductive issues. Indeed, evidence indicate that BRCA-mutated patients are not...
genetic testing
https://mbb.yale.edu/news/yale-team-finds-why-brca-gene-resists-cancer-treatment
Yale team finds why BRCA gene resists cancer treatment | Molecular Biophysics and Biochemistry
https://pure.psu.edu/en/projects/p3-paclitaxel-bevacizumb-as-1st-line-ther-locally-recurror-metast-5/
P3 PACLITAXEL +BEVACIZUMB AS 1ST-LINE THER -LOCALLY RECURROR METASTATIC BRCA EC - Penn State
https://experts.arizona.edu/en/publications/outcome-of-preventive-surgery-and-screening-for-breast-and-ovaria/fingerprints/
Outcome of preventive surgery and screening for breast and ovarian cancer in BRCA mutation carriers...
https://www.mdpi.com/2072-6694/13/11/2562
BRCA Genetic Test and Risk-Reducing Salpingo-Oophorectomy for Hereditary Breast and Ovarian Cancer:...
In the field of gynecology, the approval of the PARP inhibitors (PARPi) has been changing the treatment of ovarian cancer patients. The BRCA genetic test and...
https://pubmed.ncbi.nlm.nih.gov/28559958/
Hereditary and non-hereditary branches of family eligible for BRCA test: cancers in other sites
Members belonging to the H-branch of families of patients eligible to BRCA test have a higher risk of tumors in lung, larynx and liver. Clinicians should...
https://www.sciencedaily.com/releases/2013/01/130122142843.htm
New test predicted presence of harmful BRCA mutations | ScienceDaily
new testbrca mutationspredictedpresenceharmful
https://www.aclu.org/documents/brca-case-documents
BRCA - Case Documents | American Civil Liberties Union
case documentscivil libertiesbrcaamericanunion
https://oncofertility.msu.edu/general/brca-and-babies-the-relationship-between-breast-cancer-genes-and-fertility/
BRCA and Babies: The Relationship Between Breast Cancer Genes and Fertility - The Oncofertility...
Apr 25, 2022 - In 1990, Mary-Claire King, PhD made a groundbreaking discovery: she identified a gene that was similar in people with inherited forms of breast cancer.
the relationshipbreast cancerbrcababies
https://www.news-medical.net/news/20260417/Scientists-discover-BRCA-links-to-head-and-neck-cancer-risks.aspx
Scientists discover BRCA links to head and neck cancer risks
Apr 17, 2026 - An international group led by researchers from the RIKEN Center for Integrative Medical Sciences (IMS) in Japan have discovered associations between pathogenic...
head and neck cancerlinks toscientistsdiscoverbrca
https://pmc.ncbi.nlm.nih.gov/articles/PMC9967164/
Risk-Reducing Breast and Gynecological Surgery for BRCA Mutation Carriers: A Narrative Review - PMC
This narrative review aims to clarify the role of breast and gynecological risk-reduction surgery in BRCA mutation carriers. We examine the indications,...
https://pubmed.ncbi.nlm.nih.gov/26738429/
New concepts on BARD1: Regulator of BRCA pathways and beyond
For nearly two decades most research on BARD1 was closely linked to research on BRCA1, the breast cancer predisposition gene. The co-expression of BARD1 and...
new conceptsregulatorbrcapathwaysbeyond
https://pure.lib.usf.edu/en/publications/american-brca-outcomes-and-utilization-of-testing-about-study-a-p-2/
American BRCA Outcomes and Utilization of Testing (ABOUT) Study: A Pragmatic Research Model that...
https://pubmed.ncbi.nlm.nih.gov/30186165/
Association Between BRCA Status and Triple-Negative Breast Cancer: A Meta-Analysis
Triple-negative breast cancer (TNBC) is a subtype of aggressive breast cancer and characterized by a lack of the expression of estrogen receptor, progesterone...
triple negative breast cancer
https://news.cancerresearchuk.org/2018/10/24/targeted-drug-could-slow-progression-of-ovarian-cancer-in-women-with-faulty-brca-gene/
Targeted drug could slow progression of ovarian cancer in women with faulty BRCA gene - Cancer...
Jun 22, 2023 - A drug could help slow the progression of some advanced ovarian cancers and extend the time that patients show no signs of disease, according to new research.
https://pubchem.ncbi.nlm.nih.gov/bioassay/1963452
AID 1963452 - qHTS drug screen for cell cycle checkpoint inhibitors in PARPi-resistant BRCA-mutant...
BioAssay record AID 1963452 submitted by National Center for Advancing Translational Sciences (NCATS): qHTS drug screen for cell cycle checkpoint inhibitors in...
https://www.mdpi.com/2072-6694/14/4/897
Precision Medicine for BRCA/PALB2-Mutated Pancreatic Cancer and Emerging Strategies to Improve...
Pancreatic cancer is projected to become the second leading cause of cancer-related death by 2030. As patients typically present with advanced disease and show...
https://pubmed.ncbi.nlm.nih.gov/29337092/
Germline BRCA mutation and outcome in young-onset breast cancer (POSH): a prospective cohort study
Cancer Research UK, the UK National Cancer Research Network, the Wessex Cancer Trust, Breast Cancer Now, and the PPP Healthcare Medical Trust Grant.
https://www.nextgenelife.com/
Next Gene Life - Genome Sequencing | BRCA Screening | Genetic Testing Lab
Next Gene Life is a leading health tech company offering wide-range genetic screening and innovative genomic diagnostic and dna synthesis testing tools across...
genome sequencinggenetic testingnextlifebrca
https://www.cancerresearchuk.org/about-cancer/find-a-clinical-trial/a-study-to-find-key-messages-women-with-breast-or-ovarian-cancer-need-about-brca-gene-changes
A study to find the key messages that women with breast or ovarian cancer need about BRCA gene...
This study was for women with breast or ovarian cancer who have a change in a gene called BRCA1 or BRCA2.
https://www.brca-netzwerk.de/
BRCA-Netzwerk e.V. | Informationen zu BRCA-Mutationen
e vbrcanetzwerkinformationenzu
https://curebrca.org/
Home - BRCA
Dec 23, 2024 - Advancing the knowledge, prevention, and treatment for individuals and families who are affected by BRCA1 and BRCA2 gene mutations.
brca
https://www.justgiving.com/page/helen-vane-onefootatatime
Helen Vane is fundraising for BRCA+ Chat
Help Helen Vane raise money to support BRCA+ Chat
helenvanefundraisingbrcachat
https://pmc.ncbi.nlm.nih.gov/articles/PMC5480128/
Current guidelines for BRCA testing of breast cancer patients are insufficient to detect all...
Identification of BRCA mutations in breast cancer (BC) patients influences treatment and survival and may be of importance for their relatives. Testing is...
https://legalblogs.wolterskluwer.com/patent-blog/tag/brca/
BRCA | Tags | Kluwer Patent Blog
brcatagskluwerpatentblog
https://pubmed.ncbi.nlm.nih.gov/40869932/
Does BRCA Mutation Status Influence Ovarian Cancer Onset Timing and Patients' Treatment Outcomes?