https://pubmed.ncbi.nlm.nih.gov/22617145/
A number of genes responsible for hearing loss are related to ion recycling and homeostasis in the inner ear. Connexins (Cx26 encoded by GJB2, Cx31 encoded by...
evaluationpathogenicityvariantsassociated
https://helixlabs.ai/
Best in class Pathogenicity Prediction. Outperforms all competitors, without any tricks. Available for the full human exome, includes literature references.
helixlabsproteinvariantpathogenicity
https://sciencedaily.com/releases/2024/02/240206144907.htm
Influenza A viruses with induced resistance to a new candidate antiviral drug were found to be impaired in cell culture and weakened in animals, according to a...
flu virusantiviral drugvariantsresistantnew
https://pubmed.ncbi.nlm.nih.gov/40646002/
Pathogenicity mechanisms of the yeast Candida albicans involve filamentous growth, adhesion, invasion, and toxin production. Interestingly, clinical isolates,...
candida albicanshostalbuminredirectsmetabolism
https://www.news-medical.net/news/20230223/Pathogenicity-of-SARS-CoV-2-viral-components-on-human-periodontal-tissues-and-cells.aspx
Researchers assessed the impact of COVID-19 on fibrotic pathogenesis via the deregulation of mitochondrial beta-oxidation.
sars covpathogenicityviralcomponentshuman
https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2018.00597/full
Antibody-dependent enhancement (ADE) is a phenomenon in which pre-existing poorly neutralizing antibodies leads to enhanced infection. It is a serious concer...
zika virusfrontiersmodulationdenguepathogenicity
https://www.mdpi.com/2076-0817/14/2/149
The evolution and adaptation of highly pathogenic avian influenza (HPAI) viruses pose ongoing challenges for animal and public health. We investigated the...
avian influenzapathogenicityhighlyviruses