Robuta

Protein unfolding and aggregation at all stages as seen by NMR

Here we describe the use of electrospray differential mobility analysis (ES-DMA), also known as gas-phase electrophoretic mobility molecular analysis (GEMMA), a

Amyotrophic lateral sclerosis (ALS) is a debilitating neurodegenerative disease that targets motor neurons in the brain and spinal cord. It leads to gradual ...

Most protein sequences contain one or several short aggregation prone regions (APR) that can nucleate protein aggregation. Under normal conditions these APRs...